Channel: University of Connecticut Health Center

This collection includes bioRxiv and medRxiv papers from authors at University of Connecticut Health Center .

425 Articles

Distinct senescent β-cell senotypes differentially drive islet aging and dysfunction

Iwasaki, K., Pan, H., M. Dreyfuss, J., Jackson, M., Domanskyi, S., Baker, D., Carapeto, P., Cahill, C., Le, S., Hela, F., Alcoforado Diniz, J., Naim Eryilmaz, G., Wu, F., Wu, P.-H., Yu, B., Wirtz, D., Espinoza, S., Pena, A., G. Cigarroa, F., Abrahamian, G., Woodworth, J. L., Adams, P. D., Ucar, D., Chuang, J. H., Wu, Q., Garovic, V. D., Kirkland, J. L., Tchkonia, T., Musi, N., Kuchel, G. A., Robson, P., Aguayo-Mazzucato, C.

10.64898/2026.05.25.727705 — Posted: 2026-05-28

SnoRNA Expression and RNA 2'-O-Methylation in Drosophila melanogaster S2 Cells

Ye, X., Liu, Y., Olson, S., Zhan, L., Carmichael, G. G., Graveley, B.

10.64898/2026.05.21.726978 — Posted: 2026-05-22

Predicting 30-Day Heart Failure Readmissions Using Machine Learning: Insights From the Kansas Health Information Network (KHIN)

Kim, M., Yan, J., Wasfy, J. H., Aseltine, R.

10.64898/2026.05.18.26353537 — Posted: 2026-05-21

Targeting therapy-induced senescence across multiple breast cancer subtypes in a metastatic bone-like microenvironment

Hamburger, E. C. B., Ghazizadeh, S., Cardahi, F., Ouellet, J. A., Weber, M. H., Garzia, L., Haglund, L., Rosenzweig, D.

10.64898/2026.05.12.724653 — Posted: 2026-05-17

Adaptation of α-synuclein fibrils following multiple system atrophy transmission to mice

Mayer, M., Khedmatgozar, C. R., Zinnen, G., Frost, M. P., Reis, P. M., Holec, S. A. M., Dexter, M., Melo, A. A., Tse, E., Merz, G. E., Woerman, A. L.

10.64898/2026.05.06.723086 — Posted: 2026-05-12

USP1 inhibition promotes RAD18-dependent PCNA degradation and BRCA1 synthetic lethality

Ashton, N. W., Ravindranathan, R., Korchak, E. J., Somuncu, O. S., Zambrano, G. A., Mukkavalli, S. V., Asada, S., Korzhnev, D., Bezsonova, I., D'Andrea, A. D.

10.64898/2026.02.25.708068 — Posted: 2026-05-10

DIANNE: Segmentation-Free Localization of Histology Differential Attributes

Domanskyi, S., Rubinstein, J. C., Sheridan, T. B., Thiesen, A., Noorbakhsh, J., Alcoforado Diniz, J., Ramasamy, R., Baker, D. S., Sheldon, R., Wu, Q., Kuchel, G., Robson, P., Chuang, J. H.

10.64898/2026.04.28.721103 — Posted: 2026-05-01

Medial prefrontal cortex encodes but is not required to generate goal-directed actions under threat

Sajid, M. S., Zhou, J., Castro-Alamancos, M. A.

10.1101/2025.11.25.690391 — Posted: 2026-04-29

Mechanisms of USP7/MAGEL2 Complex Assembly and Its Mutational Disruption in Neurodevelopmental Diseases

Korchak, E. J., Soriano, G., Semenova, I., Hao, B., Stepihar, D., Bayat, T., Fon Tacer, K., Bezsonova, I.

10.64898/2026.04.24.720667 — Posted: 2026-04-28

Treponema pallidum subsp. pallidum genetic population structure and relevance to syphilis prevention and treatment

Aghakhanian, F., Lieberman, N. A. P., Hennelly, C. M., Chen, J. S., Bettin, E. B., Nunley, B. E., Chen, W., Yang, L., Matoga, M., Hoffman, I. F., Altcheh, J. M., Garcia, L. N., Rabinovich, A., Fernandez Pardal, P., Leiro, V., Manathunge, A. K. A., Elwitigala, J. P., Lukehart, S. A., Hook, E. W., Romero Leal Passos, M., Campos Arze, W. N., Boechat Andrade, H., Mulcahy, F., Wang, Q.-Q., Zhang, R.-L., Kou, C.-X., Vargas, S. K., Konda, K. A., Reyes Diaz, M., Veit Ha, T., Doanh, L. H., Nakayama, S.-I., Ohama, Y., Ohnishi, M., Yang, B., Smajs, D., Pospisilova, P., Caimano, M. J., Juliano, J. J., Moo

10.64898/2026.04.27.26351061 — Posted: 2026-04-28

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