Channel: University of California, San Francisco

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Francisco.

2875 Articles

Genome-wide CRISPR screens identify PTGES3 as a novel AR modulator

Li, H., Melnyk, J. E., Fu, B. X. H., Shrestha, R., Zhang, M., Sjostrom, M., Feng, S., Anderson, J., Han, W., Chesner, L. N., Shin, H. J., Farsh, T., Suarez, H. J., Nath, S., Chou, J., Das, R., Egusa, E. A., Calvert, M., Kishishita, A., Barpanda, A., Zhu, J., Maheshwari, A., Chen, W. S., Alshalalfa, M., Winters, A., Hua, J. T., Liu, T., Davicioni, E., Wiita, A. P., Stohr, B. A., Siddiqui, J., Huang, B., Small, E. J., Shokat, K. M., Nelson, P., Quigley, D. A., Wasmuth, E. V., Gilbert, L. A., Feng, F. Y.

10.1101/2025.05.29.656244 — Posted: 2025-05-31

Complex I Drives Glutamine-Dependent TCA Cycle to Support Viability of MYChigh Breast Cancer Cells

Anttila, J. M., Savelius, M., Somani, J., Nicorici, D., Munne, P. M., Id, L., Peura, A., Hiltunen, A. O., Aung, J., Awadhpersad, R., Prajapati, B., Peltonen, M., Ala-Hongisto, H., Gautam, P., Valimaki, M. J., Tervonen, T. A., Sapovalovaite, K., Devarajan, R., Perez, M. V. R., Mutka, M., Kovanen, P., Niinikoski, L., Meretoja, T., Mattson, J., Heikkila, P., Wennerberg, K., Arsenian-Henriksson, M., Westermarck, J., Aittokallio, T., Goga, A., Jackson, C. B., Nieminen, A. I., Klefstrom, J.

10.1101/2025.05.27.656356 — Posted: 2025-05-31

A Transcriptomics-Based Computational Drug Repositioning Pipeline Identifies Simvastatin And Primaquine As Novel Therapeutics For Endometriosis Pain

Oskotsky, T. T., Tang, X., Arthurs, E., Govil, A., Abbasi, F., Bhoja, A., Bunis, D. J., Lau, A., Einhaus, J., Diop, M., Irwin, J. C., Gaudilliere, B., Stevenson, D. K., Giudice, L. C., McAllister, S. L., Sirota, M.

10.1101/2025.05.28.656743 — Posted: 2025-05-30

Caffeine Impairs Red Blood Cell Storage Quality by Dual Inhibition of ADORA2b Signaling and G6PD Activity

Dzieciatkowska, M., Hay, A., Issaian, A., Keele, G. R., Bevers, S., Nemkov, T., Reisz, J. A., Maslanka, M., Stephenson, D., Moore, A., Deng, X., Stone, M., Hansen, K., Kleinman, S., Norris, P. J., Busch, M. P., Page, G. P., Roubinian, N. H., Xia, Y., Zimring, J. C., D'Alessandro, A.

10.1101/2025.05.27.656446 — Posted: 2025-05-30

A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity

Tsujino, S., Tsuda, M., Ito, J., Deguchi, S., Taha, T. Y., Nasser, H., Wang, L., Rosecrans, J., Suzuki, R., Suzuki, S., Yoshimatsu, K., Ott, M., The Genotype to Phenotype Japan (G2P-Japan) Consortium, , Ikeda, T., Takayama, K., Sato, K., Tanaka, S., Tamura, T., Fukuhara, T.

10.1101/2025.05.28.656516 — Posted: 2025-05-30

Advancing CNS tumor diagnostics with expanded DNA methylation-based classification

Sill, M., Schrimpf, D., Patel, A., Sturm, D., Jaeger, N., Sievers, P., Schweizer, L., Banan, R., Reuss, D., Suwala, A., Korshunov, A., Stichel, D., Wefers, A. K., Hau, A.-C., Boldt, H., Harter, P. N., Abdullaev, Z., Benhamida, J., Teichmann, D., Koch, A., Hench, J., Frank, S., Hasselblatt, M., Mansouri, S., Diaz de Stahl, T., Serrano, J., Ecker, J., Selt, F., Taylor, M., Ramaswamy, V., Cavalli, F., Berghoff, A. S., Bison, B., Blattner-Johnson, M., Buchhalter, I., Buslei, R., Calaminus, G., Dikow, N., Dohmen, H., Euskirchen, P., Fleischhack, G., Gajjar, A., Gerber, N. U., Gessi, M., Gielen, G.

10.1101/2025.05.28.25328344 — Posted: 2025-05-29

Machine Learning-Enabled EEG Biomarkers Predict Divergent Antidepressant and Placebo Response in a Clinical Trial of Major Depression

Li, Q., Detke, M., Paul, S., Potter, W., Zhang, F., Breier, A., Alphs, L., Wolkowitz, O., Ereshefsky, L., Grecco, G. G., Wang, K.

10.1101/2025.05.29.25328167 — Posted: 2025-05-29

Multivalent Lipid MVL5 Micellar Nanoparticles Exhibit Dramatically Increased Loading of Paclitaxel with PEGylation Enhancing Human Cancer Cell Penetration Depth and Cytotoxicity

Fisher, W. S., Ghasemizadeh, A., Roshan, S., Goldstein, A., Douglas, J., Perez, R., Li, Y., Ewert, K. K., Safinya, C. R.

10.1101/2025.05.24.655953 — Posted: 2025-05-29

Estimating probabilities of malaria importation in southern Mozambique through P. falciparum genomics and mobility patterns

Pujol, A., Chidimatembue, A., da Silva, C., Boene, S., Mbeve, H., Cistero, P., Garcia-Fernandez, C., Vano-Boira, A., Tembisse, D., Inacio, J., Matambisso, G., Luis, F., Ndimande, N., Munguambe, H., Nhamussua, L., Simone, W., Aranda-Diaz, A., Garcia-Ulloa, M., Canana, N., Tusell, M., Montana, J., Fuente-Soro, L., Bapu, K. U., Murphy, M., Rafael, B., Rovira-Vallbona, E., Guinovart, C., Greenhouse, B., Enosse, S. M., Saute, F., Aide, P., Candrinho, B., Mayor, A.

10.1101/2025.05.01.25326793 — Posted: 2025-05-29

Convergent large-scale network and local vulnerabilities underlie brain atrophy across Parkinson's disease stages: a worldwide ENIGMA study

Vo, A., Tremblay, C., Rahayel, S., Al-Bachari, S., Berendse, H. W., Bright, J. K., Cendes, F., d'Angremont, E., Dalrymple-Alford, J. C., Debove, I., Dirkx, M. F., Druzgal, J., Garraux, G., Helmich, R. C., Hu, M., Jahanshad, N., Johansson, M. E., Klein, J. C., Laansma, M. A., McMillan, C. T., Melzer, T. R., Misic, B., Mosley, P., Owens-Walton, C., Parkes, L. M., Pellicano, C., Piras, F., Poston, K. L., Rango, M., Rummel, C., Schwingenschuh, P., Suette, M., Thompson, P. M., Tosun, D., Tsai, C.-C., van Balkom, T. D., van den Heuvel, O. A., van der Werf, Y. D., van Heese, E. M., Vriend, C., Wang

10.1101/2025.05.25.25326586 — Posted: 2025-05-29

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