Channel: University of California, San Francisco

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Francisco.

3622 Articles

Clonal Hematopoiesis in HIV and Atherosclerosis, Arterial Inflammation, and Lymph Node Metabolic Activity

Durstenfeld, M. S., Kentoffio, K. J., Teng, A. E., Abohashem, S., Li, D., Ma, Y., Hoh, R., Deeks, S., Bick, A. G., Tawakol, A., Hsue, P. Y.

10.64898/2026.02.05.26345712 — Posted: 2026-04-30

Survey of the human proteostasis network: the ubiquitin-proteasome system

Elsasser, S., Powers, E., Stoeger, T., Sui, X., Kurtzbard, R. D., Martinez-Botia, P., Wangaline, M. A., Gama, A. R., Huttlin, E. L., Elia, L. P., Kelly, J. W., Gestwicki, J. E., Frydman, J. E., Finkbeiner, S., Clerico, E. M., Morimoto, R., Prado, M. A., Vertegaal, A. C. O., Hofmann, K., Finley, D.

10.64898/2026.03.13.711689 — Posted: 2026-04-30

Dual inhibition of GTP-bound (ON) and GDP-bound (OFF) KRASG12C suppresses PI3Kα and leads to potent tumor inhibition

Parker, K. A., Ghorbanpoor, S., Malik, W., Highfield, L., Wang, J., Hensley, E., Kelley, G., Clark, S., Ranieri, M., Sahu, S., Zhang, C., Ploszaj, M., Andrussier, D., Huang, H.-Y., Chen, T., Wang, B., Xu, R., Setoodeh, S., Lin, K., Maciag, A. E., McCormick, F., Beltran, P. J., Wong, K.-K., Stice, J. P., Sinkevicius, K. W., Hata, A. N.

10.64898/2026.04.27.718135 — Posted: 2026-04-30

Unlocking Multi-Sample Differential Expression for Spatial Transcriptomics Data with TESSERA

Constantine, F., Laszik, Z., Dudoit, S., Purdom, E.

10.64898/2026.04.27.720955 — Posted: 2026-04-30

Memory erasure by dopamine-gated retrospective learning

Jeong, H., Zsembik, L., Farouq, F., Chakraborty, R., Belur, N., Zhou, M., Sanders, A. D., Wang, S. X., Srinivasan, A., Cox, S. M. L., Garr, E., Brooke, S., Janak, P. H., Leyton, M., Chen, R., Namboodiri, V. M. K.

10.64898/2026.01.17.700100 — Posted: 2026-04-30

CRISPR-mediated functional mapping of IL2RG variants in primary human T cells predicts X-linked severe combined immunodeficiency

Rong, Y., Vysotskiy, M., Chen, P. A., Agrawal, E., Marsh, E., Wang, C. H., Carr, D., Dajani, R., Gittens Maker, B., Yu, F., Goodman, D. B., Shifrut, E., Puck, J. M., Marson, A., Nguyen, D. N.

10.64898/2026.04.27.26351884 — Posted: 2026-04-29

Engulfment by brain macrophages in a short-lived vertebrate

Nagvekar, R., Pogson, A. N., Kalakuntla, P. R., Barr, H. J., Martinez Jaimes, A. M., Perry, S. V., Costa, E. K., Chen, J., Boos, F., Navarro Negredo, P., Seeker, L. A., Jaggard, J. B., Barajas, R., Mourrain, P., Priya Singh, P., Quake, S. R., Wyss-Coray, T., Red-Horse, K., Stevens, B., Wang, B., Bedbrook, C. N., Nath, R. D., Brunet, A.

10.64898/2026.04.28.721434 — Posted: 2026-04-29

Empirical limitations of current low-intensity focused ultrasound simulation platforms

Brandts, S. D., Staveland, B., Madhusudhan, A., Ash, R. T., Di Ianni, T., Sugrue, L. P., Krystal, A. D., Moussawi, K.

10.64898/2026.01.20.26344460 — Posted: 2026-04-29

Activation of the mRNA Decay-Associated DEAD-Box ATPase Dhh1 Requires Deadenylation and Decapping Factors

Braun, G. A., Kumar, R., Hinnebusch, A. D., Gross, J. D.

10.64898/2026.04.28.721454 — Posted: 2026-04-29

MYC Overexpression Confers Sensitivity to TACC3 Inhibition for Triple-Negative Breast Cancer

Jacobo Jacobo, M., Aung, J., O'Brien, C., Rugo, H. S., Klefstrom, J., Bandyopadhyay, S., Goga, A.

10.64898/2026.04.28.721171 — Posted: 2026-04-29

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