Channel: University of California, San Francisco

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Francisco.

2355 Articles

Spliceosome profiling visualizes the operations of a dynamic RNP in vivo at nucleotide resolution

Burke, J., Longhurst, A., Merkurjev, D., Sales-Lee, J., Rao, B., Moresco, J., Yates, J., Li, J. J., Madhani, H. D.

10.1101/224170 — Posted: 2017-11-22

New routes for PTP1B allosteric inhibition by multitemperature crystallography, fragment screening and covalent tethering

Keedy, D. A., Hill, Z. B., Biel, J. T., Kang, E., Rettenmaier, T. J., Brandao-Neto, J., Pearce, N. M., von Delft, F., Wells, J. A., Fraser, J. S.

10.1101/218966 — Posted: 2017-11-13

Polymerase pausing induced by sequence-specific RNA binding protein drives heterochromatin assembly

Parsa, J.-Y., Boudoukha, S., Burke, J., Homer, C., Madhani, H.

10.1101/217968 — Posted: 2017-11-11

Metagenomics for chronic meningitis: clarifying interpretation and diagnosis

Wilson, M. R., O'Donovan, B. D., Gelfand, J. M., Sample, H. A., Chow, F. C., Betjemann, J. P., Shah, M. P., Richie, M. B., Gorman, M. P., Hajj-Ali, R. A., Calabrese, L. H., Zorn, K. C., Greenlee, J. E., Blum, J. H., Green, G., Khan, L. M., Banerji, D., Langelier, C., Bryson-Cahn, C., Harrington, W., Lingappa, J. R., Shanbhag, N. M., Green, A. J., Brew, B. J., Soldatos, A., Strnad, L., Doernberg, S. B., Jay, C. A., Douglas, V., Josephson, S. A., DeRisi, J. L.

10.1101/213561 — Posted: 2017-11-07

Protection from epidemics is a driving force for evolution of lifespan setpoints

Lidsky, P. V., Andino, R.

10.1101/215202 — Posted: 2017-11-06

Abnormal Speech Motor Control in Individuals with 16p11.2 Deletions

Demopoulos, C., Kothare, H., Mizuiri, D., Henderson-Sabes, J., Fregeau, B., Tjernagel, J., Houde, J., Sherr, E., Nagarajan, S. S.

10.1101/165316 — Posted: 2017-11-01

Robust identification of deletions in exome and genome sequence data based on clustering of Mendelian errors

Manheimer, K. B., Patel, N., Richter, F., Gorham, J., Tai, A. C., Homsy, J., Boskovski, M. T., Parfenov, M., Goldmuntz, E., Chung, W. K., Brueckner, M., Tristani-Firouzi, M., Srivastava, D., Seidman, J. G., Seidman, C. E., Gelb, B. D., Sharp, A. J.

10.1101/209478 — Posted: 2017-10-26

Hsp90 dictates viral sequence space by balancing the evolutionary tradeoffs between protein stability, aggregation and translation rate

Geller, R., Pechmann, S., Acevedo, A., Andino, R., Frydman, J.

10.1101/208462 — Posted: 2017-10-24

Light-Activated Cell Identification and Sorting (LACIS): A New Method to Identify and Select Edited Clones on a Microfluidic Device

Mocciaro, A., Roth, T., Bennett, H., Soumillon, M., Shah, A., Hiatt, J., Chapman, K., Marson, A., Lavieu, G.

10.1101/204693 — Posted: 2017-10-17

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance

Pettitt, S. J., Krastev, D. B., Brandsma, I., Drean, A., Song, F., Aleksandrov, R., Harrell, M. I., Menon, M., Brough, R., Campbell, J., Frankum, J., Ranes, M., Pemberton, H. N., Rafiq, R., Fenwick, K., Swain, A., Guettler, S., Lee, J.-M., Swisher, E. M., Stoynov, S., Yusa, K., Ashworth, A., Lord, C. J.

10.1101/203224 — Posted: 2017-10-14

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