Channel: University of California, San Francisco

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Francisco.

2766 Articles

Pharmacologic Inhibition of DYRK1A Results in MYC Hyperactivation and ERK Hyperphosphorylation rendering KMT2A-R ALL Cells Sensitive to BCL2 Inhibition

Hurtz, C., Ayyadevara, V. S. S. A., Wertheim, G., Chukinas, J., Loftus, J. P., Lee, S. J., Kumar, A., Bhansali, R. S., Swaminathan, S., Geng, H., Milne, T., Hua, X., Bernt, K. M., Besson, T., Shi, J., Crispino, J. D., Carroll, M., Tasian, S. K.

10.1101/2022.10.02.510349 — Posted: 2022-10-04

The power of TOPMed imputation for the discovery of Latino enriched rare variants associated with type 2 diabetes

Huerta-Chagoya, A., Schroeder, P., Mandla, R., Deutsch, A. J., Zhu, W., Petty, L., Yi, X., Cole, J. B., Udler, M. S., Dornbos, P., Porneala, B., DiCorpo, D., Liu, C.-T., Li, J. H., Szczerbinski, L., Kaur, V., Kim, J., Lu, Y., Martin, A., Eizirik, D. L., Marchetti, P., Marselli, L., Chen, L., Srinivasan, S., Todd, J., Flannick, J., Gubitosi-Klug, R., Levitsky, L., Shah, R., Kelsey, M., Burke, B., Dabelea, D. M., Divers, J., Marcovina, S., Stalbow, L., Loos, R. J. F., Darst, B. F., Kooperberg, C., Raffield, L. M., Haiman, C., Sun, Q., McCormick, J. B., Fisher Hoch, S. P., Ordonez, M. L., Meigs

10.1101/2022.09.30.22280535 — Posted: 2022-10-04

The cellular states and fates of shed intestinal cells

Bahar Halpern, K., Biram, A., Egozi, A., Korem Kohanim, Y., Shulman, Z., Itzkovitz, S.

10.1101/2022.10.03.510592 — Posted: 2022-10-04

Stacked binding of a small molecule PET tracer to Alzheimer's tau paired helical filaments

Merz, G. E., Chalkley, M. J., Tan, S. K., Tse, E., Lee, J., Prusiner, S. B., Paras, N. A., DeGrado, W. F., Southworth, D. R.

10.1101/2022.09.30.510175 — Posted: 2022-10-03

A Genome Scale Transcriptional Regulatory Model of the Human Placenta

Paquette, A. G., Ahuna, K., Hwang, Y. M., Pearl, J., Liao, H., Shannon, P., Kadam, L., Lapehn, S., Bucher, M., Roper, R., Funk, C. C., MacDonald, J., Bammler, T., Baloni, P., Brockway, H., Mason, W. A., Bush, N., LeWinn, K. Z., Karr, C. J., Stamatoyannopoulos, J., Muglia, L. J., Jones, H. M., Sadovsky, Y., Myatt, L., Sathyanarayana, S., Price, N., Environmental influences on Child Health Outcomes

10.1101/2022.09.27.509541 — Posted: 2022-10-03

Combinations of genes at the 16p11.2 and 22q11.2 CNVs contribute to neurobehavioral traits

Vysotskiy, M., Autism Working Group of the Psychiatric Genomics Consortium, , Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , Weiss, L. A.

10.1101/2022.09.29.22280538 — Posted: 2022-10-01

A tradeoff between enterovirus A71 particle stability and cell entry

Catching, A., Yeh, M. T., Bianco, S., Capponi, S., Andino, R.

10.1101/2022.09.28.506941 — Posted: 2022-09-30

A scalable screening platform for phenotypic subtyping of ALS patient-derived fibroblasts

Kumbier, K., Roth, M., Li, Z., Lazzari-Dean, J., Waters, C., Huang, P., Korobeynikov, V., ALS Consortium, N. Y. G. C., Phatnani, H., Shneider, N., Jacobson, M. P., Wu, L., Altschuler, S.

10.1101/2022.09.27.509770 — Posted: 2022-09-30

Smartphone ownership and use among pregnant women with HIV in South Africa

Noholoza, S., Phillips, T. K., Madwayi, S., Mrubata, M., Camlin, C. S., Myer, L., Clouse, K.

10.1101/2022.09.29.22280417 — Posted: 2022-09-30

Genetic Regulators of Sputum Mucin Concentration and Their Associations with COPD Phenotypes

Van Buren, E., Radicioni, G., Lester, S., O'Neal, W., Dang, H., Kasela, S., Gardadri, S., Curtis, J., Han, M., Krishnan, J., Wan, E., Silverman, E., Hastie, A., Ortega, V., Lappalainen, T., Christenson, S., Li, Y., Cho, M., Kesimer, M., Kelada, S.

10.1101/2022.09.28.509838 — Posted: 2022-09-30

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