bioRxiv/medRxiv TRiP Review Activity

381 Reviews — eLife — Biochemistry

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CCL25 targeting by de novo protein binders differentially suppress CCR9 and ACKR4 activation and transform CCL25 into a biased agonist
de Boer, B., Lamme, T. D., Verdwaald, K., Santamaria Medina, S., Nemeth, C. G., Elfrink, E. M., Smit, M. J., de Esch, I. J., Schafer, C. T.
10.64898/2026.01.23.701245 — Posted: 2026-01-23 — Discussion: 2026-05-05  eLife
Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling
Zacharia, N. K., Kuhns, S., Boegholm, N., Christensen, A., Wang, J., Petriman, N. A., Lorentzen, A., Fialova, J. L., Menguy, L., Saunier, S., Christensen, S. T., Andersen, J. S., Bhogaraju, S., lorentzen, e.
10.1101/2024.11.05.620812 — Posted: 2024-11-05 — Discussion: 2026-05-05  eLife
Purified Zymogens Reveal Mechanisms of Snake Venom Metalloproteinase Auto-Activation
Hall, S., Cardoso, I. A., Wilkinson, M. C., Carretero, M. M., Lingappa, S., Rand, B., Shen, D., Boldrini-Franca, J., Stenner, R., Menzies, S. K., Balchin, G., Hus, K. K., Vincentelli, R., Mumford, A., Casewell, N. R., Berger, I., Schaffitzel, C.
10.1101/2025.06.27.661748 — Posted: 2025-09-03 — Discussion: 2026-05-05  eLife
Nuclear CK1δ as a Critical Determinant of PER:CRY Complex Dynamics and Circadian Period
Serrano, F. E., Marzoll, D., Ruppert, B., Diernfellner, A., Brunner, M.
10.1101/2025.02.12.637842 — Posted: 2025-02-13 — Discussion: 2026-04-30  eLife
The structure of Egalitarian in complex with the K10 mRNA localization signal reveals a modular binding surface required for function
Hong, Z., Jin, L., Muehle, J., Bono, F.
10.1101/2025.08.03.668247 — Posted: 2025-08-03 — Discussion: 2026-04-24  eLife
The Structural Dynamics of IRE1 and its Interaction with Unfolded Peptides
Spinetti, E., Karagöz, G. E., Covino, R.
10.1101/2025.02.28.640832 — Posted: 2025-03-03 — Discussion: 2026-04-22  eLife
A simplified and highly efficient cell-free protein synthesis system for prokaryotes
Lang, X., Zhang, C., Lin, J., Zhang, Z., Li, W.
10.1101/2025.09.12.675764 — Posted: 2025-09-12 — Discussion: 2026-04-20  eLife
Multifaceted Functional Complexity of SARS-CoV-2 Helicase Nsp13 Underlies Its Integrated Motor and Remodeling Activities
Li, H., Hou, J., Yu, X., Jin, J., Hou, X.-M.
10.64898/2026.01.26.701677 — Posted: 2026-01-26 — Discussion: 2026-04-20  eLife
Towards a unified molecular mechanism for ligand-dependent activation of NR4A-RXR heterodimers
Yu, X., He, Y., Kamenecka, T. M., Kojetin, D. J.
10.1101/2025.03.19.642122 — Posted: 2025-03-19 — Discussion: 2026-04-17  eLife
Gβγ engages PLCβ3 at multiple sites to reorient and facilitate its activation
Fisher, I. J., Senarath, K., Outlaw, K., Muralidharan, K., Garland-Kuntz, E. E., Van Camp, M. M., Komay, T., Inoue, A., Kostenis, E., Lambert, N. A., Lyon, A.
10.64898/2026.01.14.699417 — Posted: 2026-01-16 — Discussion: 2026-04-10  eLife

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