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373 Reviews — eLife — Biochemistry

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Purified Zymogens Reveal Mechanisms of Snake Venom Metalloproteinase Auto-Activation
Hall, S., Cardoso, I. A., Wilkinson, M. C., Carretero, M. M., Lingappa, S., Rand, B., Shen, D., Boldrini-Franca, J., Stenner, R., Menzies, S. K., Balchin, G., Hus, K. K., Vincentelli, R., Mumford, A., Casewell, N. R., Berger, I., Schaffitzel, C.
10.1101/2025.06.27.661748 — Posted: 2025-09-03 — Discussion: 2026-01-21  eLife
Structure of the human CTF18 clamp loader bound to PCNA
Briola, G., Tehseen, M., Al-Amodi, A., Nguyen, P. Q., Savva, C. G., Hamdan, S. M., De Biasio, A.
10.1101/2024.05.08.593111 — Posted: 2024-05-09 — Discussion: 2026-01-20  eLife
Shifting the PPARγ conformational ensemble towards a transcriptionally repressive state improves covalent inhibitor efficacy
Arifova, L., MacTavish, B. S., Laughlin, Z., Karadi Girdhar, M. N., Shang, J., Li, M.-H., Yu, X., Zhu, D., Kamenecka, T. M., Kojetin, D.
10.1101/2025.03.04.640448 — Posted: 2025-03-05 — Discussion: 2025-12-31  eLife
A high-resolution analysis of arrestin2 interactions responsible for CCR5 endocytosis
Petrovic, I., Desai, S., Isaikina, P., Abiko, L. A., Spang, A., Grzesiek, S.
10.1101/2024.11.04.621860 — Posted: 2024-11-04 — Discussion: 2025-12-22  eLife
Identification of the Regulatory Elements and Protein Substrates of Lysine Acetoacetylation
Fu, Q., Nguyen, T., Kumar, B., Azadi, P., Zheng, Y. G.
10.1101/2024.10.31.621296 — Posted: 2024-10-31 — Discussion: 2025-12-18  eLife
A simplified and highly efficient cell-free protein synthesis system for prokaryotes
Lang, X., Zhang, C., Lin, J., Zhang, Z., Li, W.
10.1101/2025.09.12.675764 — Posted: 2025-09-12 — Discussion: 2025-12-11  eLife
Cryo-EM structure of the bicarbonate receptor GPR30
Kaneda, S., Jo-Watanabe, A., Akasaka, H., Oshima, H. S., Yokomizo, T., Shihoya, W., Nureki, O.
10.1101/2024.05.19.594840 — Posted: 2024-05-19 — Discussion: 2025-12-11  eLife
ATP-independent phosphate recycling on AGC kinase activation loops induced by alkali metal ions
Kubouchi, K., Mukai, H.
10.1101/2025.09.04.674365 — Posted: 2025-09-06 — Discussion: 2025-11-21  eLife
Gut Microbe-Derived Trimethylamine Shapes Circadian Rhythms Through the Host Receptor TAAR5
Mahen, K. K., Massey, W. J., Orabi, D., Brown, A. L., Jaramillo, T. C., Burrows, A., Horak, A. J., Dutta, S., Mrdjen, M., Mouannes, N., Varadharajan, V., Osborne, L. J., Ye, X., Yarbrough, D. M., Grubb, T., Zajczenko, N., Hohe, R., Banerjee, R., Linga, P., Laungani, D., Hajjar, A., Sangwan, N., Dwidar, M., Buffa, J. A., Swanson, G. R., Wang, Z., Brown, J. M.
10.1101/2025.04.03.647082 — Posted: 2025-04-08 — Discussion: 2025-11-21  eLife
Molecular mechanism for cargo-mediated initiation of kinesin-1 activation
Shukla, S., Cross, J. A., Kish, M., Yadav, S. K., Weijman, J. F., O'Regan, L., Mantell, J., Borucu, U., Leng, X., Schaffitzel, C., Phillips, J. J., Woolfson, D. N., Dodding, M. P.
10.1101/2025.04.08.647705 — Posted: 2025-04-08 — Discussion: 2025-11-18  eLife

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