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348 Reviews — eLife — Biochemistry

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Towards a unified molecular mechanism for ligand-dependent activation of NR4A-RXR heterodimers
Yu, X., He, Y., Kamenecka, T. M., Kojetin, D. J.
10.1101/2025.03.19.642122 — Posted: 2025-03-19 — Discussion: 2025-05-22  eLife
Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IkappaBalpha without requiring ATP
Polley, S., Borar, P., Biswas, T., Huxford, T., Ghosh, G.
10.1101/2023.06.27.546692 — Posted: 2023-06-27 — Discussion: 2025-05-21  eLife
Growth inhibitory factor/metallothionein-3 is a sulfane sulfur-binding protein
Shinkai, Y., Ding, Y., Matsui, T., Devitt, G., Akiyama, M., Shen, T.-L., Nishida, M., Ida, T., Akaike, T., Mahajan, S., Fukuto, J. M., Shigeta, Y., Kumagai, Y.
10.1101/2023.10.19.563042 — Posted: 2023-10-19 — Discussion: 2025-05-14  eLife
Epitope Sequence and Modification Fingerprints of Anti-Aβ Antibodies
Talucci, I., Leske, T., Klafki, H.-W., Hassan, M. M., Steiert, A., Morgado, B., Bothe, S., van Werven, L., Liepold, T., Walter, J., Schindelin, H., Wiltfang, J., Wirths, O., Jahn, O., Maric, H. M.
10.1101/2025.02.26.640323 — Posted: 2025-03-03 — Discussion: 2025-05-09  eLife
Blue-shifted ancyromonad channelrhodopsins for multiplex optogenetics
Govorunova, E. G., Sineshchekov, O. A., Li, H., Gou, Y., Chen, H., Yang, S., Wang, Y., Mitchell, S., Palmateer, A., S. Brown, L. S., St-Pierre, F., Xue, M. G., Spudich, J. L.
10.1101/2025.02.24.639930 — Posted: 2025-03-01 — Discussion: 2025-05-09  eLife
Targeted Protein Degradation by KLHDC2 Ligands Identified by High Throughput Screening
Zhou, H., Zhou, T., Yu, W., Liu, L., Ko, Y., Johnson, K. A., Wilson, I. A., Schultz, P. G., Bollong, M. J.
10.1101/2025.03.31.646306 — Posted: 2025-04-01 — Discussion: 2025-05-09  eLife
The alternative oxidase reconfigures the larval mitochondrial electron transport system to accelerate growth and development in Drosophila melanogaster
Garcia, G. S., Othonicar, M. F., Campos, A. T. P., Kilbourn, E. A., Bicego, K. C., Lerchner, J., Tennessen, J. M., Oliveira, M. T.
10.1101/2025.02.20.639223 — Posted: 2025-02-23 — Discussion: 2025-05-09  eLife
Shifting the PPARγ conformational ensemble towards a transcriptionally repressive state improves covalent inhibitor efficacy
Arifova, L., MacTavish, B. S., Laughlin, Z., Karadi Girdhar, M. N., Shang, J., Li, M.-H., Yu, X., Zhu, D., Kamenecka, T. M., Kojetin, D.
10.1101/2025.03.04.640448 — Posted: 2025-03-05 — Discussion: 2025-05-08  eLife
Coupled equilibria of dimerization and lipid binding modulate SARS Cov 2 Orf9b interactions and interferon response
San Felipe, C., Batra, J., Muralidharan, M., Malpotra, S., Anand, D., Bauer, R., Verba, K. A., Swaney, D. L., Krogan, N. J., Grabe, M., Fraser, J. S.
10.1101/2025.02.16.638509 — Posted: 2025-02-17 — Discussion: 2025-05-07  eLife
Identification of the Regulatory Elements and Protein Substrates of Lysine Acetoacetylation
Fu, Q., Nguyen, T., Kumar, B., Azadi, P., Zheng, Y. G.
10.1101/2024.10.31.621296 — Posted: 2024-10-31 — Discussion: 2025-04-22  eLife

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