bioRxiv/medRxiv TRiP Review Activity

525 Reviews — All Partners — Biochemistry

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Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia.
Joseph, R. E., Wales, T. E., Jayne, S., Britton, R. G., Fulton, D. B., Engen, J. R., Dyer, M. J. S., Andreotti, A.
10.1101/2023.12.18.572223 — Posted: 2023-12-18 — Discussion: 2024-11-14  eLife
Structure of human PIEZO1 and its slow inactivating channelopathy mutants
Shan, Y., Guo, X., Zhang, M., Chen, M., Li, Y., Zhang, M., Pei, D.
10.1101/2024.07.14.603468 — Posted: 2024-07-16 — Discussion: 2024-11-14  eLife
Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis
Blackwell, A. M., Jami-Alahmadi, Y., Nasamu, A. S., Kudo, S., Senoo, A., Slam, C., Tsumoto, K., Wohlschlegel, J. A., Caaveiro, J. M. M., Goldberg, D. E., Sigala, P. A.
10.1101/2024.05.30.596652 — Posted: 2024-05-31 — Discussion: 2024-11-13  eLife
Naa80 is required for actin N-terminal acetylation and normal hearing in zebrafish
Ree, R., Lin, S.-J., Sti Dahl, L. O., Huang, K., Petree, C., Varshney, G. K., Arnesen, T.
10.1101/2024.03.17.585386 — Posted: 2024-03-17 — Discussion: 2024-11-01  EMBO Press
The hGID GID4 E3 ubiquitin ligase complex targets ARHGAP11A to regulate cell migration
Bagci, H., Winkler, M., Uliana, F., Boulais, J., Mohamed, W. I., Park, S. L., Cote, J.-F., Peter, M.
10.1101/2023.07.20.549906 — Posted: 2023-07-20 — Discussion: 2024-11-01  EMBO Press
A new class of receptors: Lipids regulate mammalian Gsalpha-stimulated adenylyl cyclase activities via their membrane anchors
Landau, M., Elsabbagh, S., Gross, H., Fuchs, A. C. D., Schultz, A., Schultz, J. E.
10.1101/2024.08.06.606792 — Posted: 2024-08-07 — Discussion: 2024-10-23  eLife
Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARgamma
Shang, J., Kojetin, D.
10.1101/2024.05.15.594037 — Posted: 2024-05-15 — Discussion: 2024-10-18  eLife
Structural insights into human propionyl-CoA carboxylase (PCC) and 3-methylcrotonyl-CoA carboxylase (MCC)
Zhou, F., Zhang, Y., Zhu, Y., Zhou, Q., Shi, Y., Hu, Q.
10.1101/2024.04.30.591959 — Posted: 2024-05-02 — Discussion: 2024-10-10  eLife
A quantitative comparison of human embryonic and induced stem cell proteomes
Brenes, A. J., Griesser, E. J., Sinclair, L. V., Jiang, H., Yoshikawa, H., Davidson, L., Platani, M., Swedlow, J., Cantrell, D. A., Lamond, A. I.
10.1101/2021.10.20.464767 — Posted: 2021-10-20 — Discussion: 2024-10-08  eLife
Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays
Van Vranken, J. G., Li, J., Mintseris, J., Gadzuk-Shea, M., Gygi, S. P., Schweppe, D.
10.1101/2024.01.26.577428 — Posted: 2024-01-27 — Discussion: 2024-10-07  eLife

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