bioRxiv/medRxiv TRiP Review Activity

562 Reviews — All Partners — Biochemistry

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Allosteric modulation of dimeric GPR3 by ligands in the dimerization interface
Qiu, Z., Wang, W., Nie, Y., Lin, J., Zhang, B., Xing, H., Zheng, S.
10.1101/2025.04.19.649678 — Posted: 2025-04-20 — Discussion: 2025-07-21  eLife
Structural insights into inherited anemia CDA-I: disease-associated mutations disrupt CDIN1-Codanin1 complex
Stojaspal, M., Brom, T., Janovic, T., Necasova, I., Veverka, P., Uhrik, L., Hernychova, L., Hofr, C.
10.1101/2023.05.25.542057 — Posted: 2023-05-26 — Discussion: 2025-07-17  Review Commons
Occupancy of the HbYX hydrophobic pocket is sufficient to induce gate opening in the archaeal 20S proteasomes.
Chuah, J. J. Y., Daugherty, M. R., Smith, D. M.
10.1101/2024.05.21.595185 — Posted: 2024-05-21 — Discussion: 2025-07-07  eLife
Phage-displayed synthetic library and screening platform for nanobody discovery
Xia, B., Kim, A.-R., Liu, F., Han, M., Stoneburner, E., Makdissi, S., Di Cara, F., Mohr, S., Ring, A., Perrimon, N.
10.1101/2024.12.20.629765 — Posted: 2024-12-21 — Discussion: 2025-06-20  eLife
Elevated Ubiquitin Phosphorylation by PINK1 Contributes to Proteasomal Impairment and Promotes Neurodegeneration
Chen, C., Gao, T.-Y., Yi, H.-W., Zhang, Y., Wang, T., Lou, Z.-L., Wei, T.-F., Lu, Y.-B., Li, T., Tang, C., Zhang, W.-P.
10.1101/2024.10.18.619025 — Posted: 2024-10-19 — Discussion: 2025-06-12  eLife
Conformational dynamics and asymmetry in multimodal inhibition of membrane-bound pyrophosphatases
Vidilaseris, K., Ma, Y., Hardman, K., Johansson, N. G., De Castro Ribeiro, O. M., Yli-Kauhaluoma, J., Xhaard, H., Jeuken, L. J. C., Brookfield, A., Bowen, A., Liu, J., -, , Shah, A., Pliotas, C.
10.1101/2024.07.26.605302 — Posted: 2024-07-26 — Discussion: 2025-06-11  eLife
Mapping Cryptic Phosphorylation Sites in the Human Proteome
Gasparotto, D., Zanon, A., Bonaldo, V., Marchiori, E., Casagranda, M., Di Domenico, E., Copat, L., Asquini, T. F., Rigoli, M., Feltrin, S. V., Lorenzo, N. L., Lolli, G., Pennuto, M., Requena, J. R., Stabelli, O. R., Minervini, G., Micheletti, C., Spagnolli, G., Faccioli, P., Biasini, E.
10.1101/2024.12.03.626562 — Posted: 2024-12-04 — Discussion: 2025-06-06  Review Commons
Structural insights into heterohexameric assembly of epilepsy-related ligand-receptor complex LGI1-ADAM22
Yamaguchi, T., Okatsu, K., Kubota, M., Mitsumori, A., Yamagata, A., Fukata, Y., Fukata, M., Shibata, M., Fukai, S.
10.1101/2025.01.06.631603 — Posted: 2025-01-08 — Discussion: 2025-05-30  eLife
Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IkappaBalpha without requiring ATP
Polley, S., Borar, P., Biswas, T., Huxford, T., Ghosh, G.
10.1101/2023.06.27.546692 — Posted: 2023-06-27 — Discussion: 2025-05-21  eLife
The late onset Alzheimer's disease risk factor iRhom2/RHBDF2 is a modifier of microglial TREM2 proteolysis
Jocher, G., Lichtenthaler, S. F., Müller, S. A., Hsia, H.-E., Lastra-Osua, M., Özcelik, G., Hofmann, L. I., Assfalg, M., Dinkel, L., Schlepckow, K., Willem, M., Haass, C., Tahirovic, S., Blobel, C. P., Feng, X.
10.1101/2024.09.13.612888 — Posted: 2024-09-16 — Discussion: 2025-05-20  EMBO Press

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