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539 Reviews — All Partners — Biochemistry

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Proximity Interactome analyses unveil novel regulators of IRE1a canonical signaling
Le Goupil, S., Philippe, C., Laprade, H., Lode, M., Boniface, R., Pelizzari-Raymundo, D., Dejgaard, K., Jansen, G., Limia, C., Hetz, C., Mahdizadeh, S. J., Negroni, L., AUBRY, M., Ricci, J.-E., Eriksson, L. A., chevet, e.
10.1101/2024.10.27.620453 — Posted: 2024-10-28 — Discussion: 2025-02-02  Review Commons
Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling
Zacharia, N. K., Kuhns, S., Boegholm, N., Christensen, A., Wang, J., Petriman, N. A., Lorentzen, A., Fialova, J. L., Menguy, L., Saunier, S., Christensen, S. T., Andersen, J. S., Bhogaraju, S., lorentzen, e.
10.1101/2024.11.05.620812 — Posted: 2024-11-05 — Discussion: 2025-01-30  eLife
Reduction of DNA Topoisomerase Top2 reprograms the epigenetic landscape and extends health and life span across species
Zhu, M., Ma, M., Luo, L., Li, F., Zhang, J., Pan, Y., Yang, L., Xiao, Y., Wang, Z., Xian, B., Zheng, Y., Li, H., Yang, J.
10.1101/2024.11.14.623693 — Posted: 2024-11-15 — Discussion: 2025-01-22  eLife
Molecular determinants of Neu5Ac binding to tripartite ATP independent periplasmic (TRAP) transporter
Goyal, P., Dhanabalan, K., Scalise, M., Friemann, R., Indiveri, C., Dobson, R. C., Vinothkumar, K. R., Subramanian, R.
10.1101/2024.03.29.587382 — Posted: 2024-03-30 — Discussion: 2025-01-22  eLife
Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production
Arafi, P., Devkota, S., Maesako, M., Wolfe, M. S.
10.1101/2024.08.30.610520 — Posted: 2024-08-31 — Discussion: 2025-01-17  eLife
Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome
Cozzolino, K., Sanford, L., Hunter, S., Molison, K., Erickson, B., Jones, T., Ajit, D., Galbraith, M. D., Espinosa, J. M., Bentley, D. L., Allen, M. A., Dowell, R. D. A., Taatjes, D. J.
10.1101/2023.07.05.547813 — Posted: 2023-07-05 — Discussion: 2025-01-17  eLife
Interaction hierarchy among Cdv proteins drives recruitment to membrane necks
De Franceschi, N., Blanch-Jover, A., Dekker, C.
10.1101/2024.10.03.616404 — Posted: 2024-10-03 — Discussion: 2025-01-16  eLife
The conserved biochemical activity and function of an early metazoan phosphatidylinositol 5 phosphate 4-kinase regulates growth and development.
Krishnan, H., Muzaffar, S., Sharma, S., Ramya, V., Ghosh, A., Sowdhamini, R., PADINJAT, R.
10.1101/2024.08.01.606031 — Posted: 2024-08-01 — Discussion: 2025-01-03  Review Commons
Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant
Tomlinson, P. R., Knox, R., Perisic, O., Su, H., Brierley, G. V., Williams, R. L., Semple, R. K.
10.1101/2023.11.02.565250 — Posted: 2023-11-02 — Discussion: 2025-01-03  eLife
4G cloning: rapid gene assembly for expression of multisubunit protein complexes in diverse hosts
Taschner, M., Dickinson, J. B., Roisne-Hamelin, F., Gruber, S.
10.1101/2024.06.17.599261 — Posted: 2024-06-17 — Discussion: 2024-12-14  EMBO Press

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