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348 Reviews — eLife — Biochemistry

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The chromokinesin Kid forms a homodimer and moves processively along microtubules
Niwa, S., Furusaki, N., Kita, T., Chiba, K.
10.1101/2024.03.13.584902 — Posted: 2024-03-13 — Discussion: 2024-11-19  eLife
Identification of Suitable Target/E3 Ligase Pairs for PROTAC Development using a Rapamycin-induced Proximity Assay (RiPA)
Adhikari, B., Schneider, K., Diebold, M., Sotriffer, C., Wolf, E.
10.1101/2024.04.24.590940 — Posted: 2024-04-25 — Discussion: 2024-11-18  eLife
Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50
Paz, E., Jain, S., Gottfried, I., Staretz-Chacham, O., Mahajnah, M., Bagchi, P., Seyfried, N., Ashery, U., Azem, A.
10.1101/2024.05.20.594480 — Posted: 2024-05-20 — Discussion: 2024-11-18  eLife
Structure of human PIEZO1 and its slow inactivating channelopathy mutants
Shan, Y., Guo, X., Zhang, M., Chen, M., Li, Y., Zhang, M., Pei, D.
10.1101/2024.07.14.603468 — Posted: 2024-07-16 — Discussion: 2024-11-14  eLife
Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia.
Joseph, R. E., Wales, T. E., Jayne, S., Britton, R. G., Fulton, D. B., Engen, J. R., Dyer, M. J. S., Andreotti, A.
10.1101/2023.12.18.572223 — Posted: 2023-12-18 — Discussion: 2024-11-14  eLife
Biochemical and structural insights into the auto-inhibited state of Mical1 and its activation by Rab8
Rai, A., Janning, P., Vetter, I. R., Goody, R. S.
10.1101/2024.06.17.599268 — Posted: 2024-06-17 — Discussion: 2024-11-14  eLife
Distinct mechanisms of inhibition of Kv2 potassium channels by tetraethylammonium and RY785
Zhang, S., Stix, R., Orabi, E. A., Bernhardt, N., Faraldo-Gomez, J. D.
10.1101/2024.07.25.605170 — Posted: 2024-07-25 — Discussion: 2024-11-14  eLife
Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis
Blackwell, A. M., Jami-Alahmadi, Y., Nasamu, A. S., Kudo, S., Senoo, A., Slam, C., Tsumoto, K., Wohlschlegel, J. A., Caaveiro, J. M. M., Goldberg, D. E., Sigala, P. A.
10.1101/2024.05.30.596652 — Posted: 2024-05-31 — Discussion: 2024-11-13  eLife
A new class of receptors: Lipids regulate mammalian Gsalpha-stimulated adenylyl cyclase activities via their membrane anchors
Landau, M., Elsabbagh, S., Gross, H., Fuchs, A. C. D., Schultz, A., Schultz, J. E.
10.1101/2024.08.06.606792 — Posted: 2024-08-07 — Discussion: 2024-10-23  eLife
Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARgamma
Shang, J., Kojetin, D.
10.1101/2024.05.15.594037 — Posted: 2024-05-15 — Discussion: 2024-10-18  eLife

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