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370 Reviews — eLife — Biochemistry

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The Structural Dynamics of IRE1 and its Interaction with Unfolded Peptides
Spinetti, E., Karagöz, G. E., Covino, R.
10.1101/2025.02.28.640832 — Posted: 2025-03-03 — Discussion: 2025-06-12  eLife
Elevated Ubiquitin Phosphorylation by PINK1 Contributes to Proteasomal Impairment and Promotes Neurodegeneration
Chen, C., Gao, T.-Y., Yi, H.-W., Zhang, Y., Wang, T., Lou, Z.-L., Wei, T.-F., Lu, Y.-B., Li, T., Tang, C., Zhang, W.-P.
10.1101/2024.10.18.619025 — Posted: 2024-10-19 — Discussion: 2025-06-12  eLife
Conformational dynamics and asymmetry in multimodal inhibition of membrane-bound pyrophosphatases
Vidilaseris, K., Ma, Y., Hardman, K., Johansson, N. G., De Castro Ribeiro, O. M., Yli-Kauhaluoma, J., Xhaard, H., Jeuken, L. J. C., Brookfield, A., Bowen, A., Liu, J., -, , Shah, A., Pliotas, C.
10.1101/2024.07.26.605302 — Posted: 2024-07-26 — Discussion: 2025-06-11  eLife
Structural insights into heterohexameric assembly of epilepsy-related ligand-receptor complex LGI1-ADAM22
Yamaguchi, T., Okatsu, K., Kubota, M., Mitsumori, A., Yamagata, A., Fukata, Y., Fukata, M., Shibata, M., Fukai, S.
10.1101/2025.01.06.631603 — Posted: 2025-01-08 — Discussion: 2025-05-30  eLife
Membrane curvature regulates Ups1 dependent phosphatidic acid transfer across lipid bilayers
Sadeqi, F., Dong, D., Stroh, K., Vache, M., Metz, J., Riedel, D., Janshoff, A., Risselada, H. J., Kolenda, C., Meinecke, M.
10.1101/2025.04.03.647039 — Posted: 2025-04-04 — Discussion: 2025-05-27  eLife
Towards a unified molecular mechanism for ligand-dependent activation of NR4A-RXR heterodimers
Yu, X., He, Y., Kamenecka, T. M., Kojetin, D. J.
10.1101/2025.03.19.642122 — Posted: 2025-03-19 — Discussion: 2025-05-22  eLife
Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IkappaBalpha without requiring ATP
Polley, S., Borar, P., Biswas, T., Huxford, T., Ghosh, G.
10.1101/2023.06.27.546692 — Posted: 2023-06-27 — Discussion: 2025-05-21  eLife
Growth inhibitory factor/metallothionein-3 is a sulfane sulfur-binding protein
Shinkai, Y., Ding, Y., Matsui, T., Devitt, G., Akiyama, M., Shen, T.-L., Nishida, M., Ida, T., Akaike, T., Mahajan, S., Fukuto, J. M., Shigeta, Y., Kumagai, Y.
10.1101/2023.10.19.563042 — Posted: 2023-10-19 — Discussion: 2025-05-14  eLife
Targeted Protein Degradation by KLHDC2 Ligands Identified by High Throughput Screening
Zhou, H., Zhou, T., Yu, W., Liu, L., Ko, Y., Johnson, K. A., Wilson, I. A., Schultz, P. G., Bollong, M. J.
10.1101/2025.03.31.646306 — Posted: 2025-04-01 — Discussion: 2025-05-09  eLife
The alternative oxidase reconfigures the larval mitochondrial electron transport system to accelerate growth and development in Drosophila melanogaster
Garcia, G. S., Othonicar, M. F., Campos, A. T. P., Kilbourn, E. A., Bicego, K. C., Lerchner, J., Tennessen, J. M., Oliveira, M. T.
10.1101/2025.02.20.639223 — Posted: 2025-02-23 — Discussion: 2025-05-09  eLife

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