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525 Reviews — All Partners — Biochemistry

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Structure-based design and characterization of Parkin activating mutations
Trempe, J.-F., Stevens, M. U., Croteau, N., Eldeeb, M. A., Zeng, Z. W., Toth, R., Durcan, T. M., Springer, W., Fon, E. A., Muqit, M. M. K.
10.1101/2022.02.22.481412 — Posted: 2022-02-22 — Discussion: 2023-06-28  EMBO Press
Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor
De Gieter, S., Wijckmans, E., Pasini, D., Ulens, C., Efremov, R. G.
10.1101/2023.01.06.523009 — Posted: 2023-01-06 — Discussion: 2023-06-22  eLife
Nuclear bodies protect phase separated proteins from degradation in stressed proteome
Jung, K. H., Sun, J., Hsiung, C.-H., Lian, X., Liu, Y., Zhang, X.
10.1101/2023.04.19.537522 — Posted: 2023-04-21 — Discussion: 2023-06-21  eLife
Genome-wide screen reveals Rab12 GTPase as a critical activator of pathogenic LRRK2 kinase
Dhekne, H. S., Tonelli, F., Yeshaw, W. M., Chiang, C. Y., Limouse, C., Jaimon, E., Purlyte, E., Alessi, D. R., Pfeffer, S. R.
10.1101/2023.02.17.529028 — Posted: 2023-02-18 — Discussion: 2023-06-17  eLife
Structural insights into pore dynamics of human Pannexin isoforms
Hussain, N., Apotikar, A., Pidathala, S., Mukherjee, S., Burada, A. P., Sikdar, S. K., Kutti, V. R., Penmatsa, A.
10.1101/2022.09.09.507385 — Posted: 2022-09-10 — Discussion: 2023-06-16  Biophysics Colab
Stable kinetochore-microtubule attachment requires loop-dependent Ndc80-Ndc80 binding
Polley, S., Müschenborn, H., Terbeck, M., De Antoni, A., Vetter, I. R., Dogterom, M., Musacchio, A., Volkov, V. A., Huis in 't Veld, P. J.
10.1101/2022.08.25.505310 — Posted: 2022-08-26 — Discussion: 2023-06-15  EMBO Press
ChIP-MS reveals the local chromatin composition by label-free quantitative proteomics
Yong, W. K., Rane, G., Zaal Anuar, N., Shao, X., Goh, C. Y., Khanchandani, V., Kuan, V. L. S., Jeitany, M., Koeffler, P., Deng, L.-W., Sanda, T., Kappei, D.
10.1101/2023.01.27.525999 — Posted: 2023-01-28 — Discussion: 2023-06-15  Review Commons
Conformational dynamics and target-dependent myristoyl switch of calcineurin B homologous protein 3
Becker, F., Fuchs, S., Refisch, L., Drepper, F., Bildl, W., Schulte, U., Liang, S., Heinicke, J. I., Hansen, S. C., Kreutz, C., Warscheid, B., Fakler, B., Mymrikov, E. V., Hunte, C.
10.1101/2022.09.23.509142 — Posted: 2022-09-23 — Discussion: 2023-06-12  eLife
Metabolic response to point mutations reveals principles of modulation of in vivo enzyme activity and phenotype
Bhattacharyya, S., Bershtein, S., Adkar, B. V., Woodard, J., Shakhnovich, E.
10.1101/738823 — Posted: 2020-12-16 — Discussion: 2023-06-10  EMBO Press
Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain
Harris, N. J., Jenkins, M. L., Nam, S.-E., Rathinaswamy, M. K., Parson, M. A., Ranga-Prasad, H., Dalwadi, U., Moeller, B. E., Sheeky, E., Hansen, S. D., Yip, C. K., Burke, J. E.
10.1101/2023.04.12.536585 — Posted: 2023-04-12 — Discussion: 2023-06-09  eLife

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