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547 Reviews — All Partners — Biochemistry

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An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor
Aguirre, T., Hostachy, S., Dornan, G. L., Neuenschwander, M., Seyffarth, C., Haucke, V., Schuetz, A., von Kries, J. P., Fiedler, D.
10.1101/2023.04.26.538378 — Posted: 2023-04-26 — Discussion: 2023-09-20  eLife
MEMO1 is a Metal Containing Regulator of Iron Homeostasis in Cancer Cells
Dolgova, N., Uhlemann, E.-M. E., Boniecki, M. T., Vizeacoumar, F. S., Ralle, M., Tonelli, M., Abbas, S. A., Patry, J., Elhasasna, H., Freywald, A., Vizeacoumar, F., Dmitriev, O. Y.
10.1101/2023.02.28.530460 — Posted: 2023-02-28 — Discussion: 2023-09-19  eLife
The GEF Cdc24 and GAP Rga2 synergistically regulate Cdc42 GTPase cycling
Tschirpke, S., Daalman, W. K.-G., Laan, L.
10.1101/2023.06.26.546500 — Posted: 2023-06-28 — Discussion: 2023-09-19  Review Commons
Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stresses
Wang, J., Wen, Y., Zhao, W., Zhang, Y., Lin, F., Ouyang, C., Wang, H., Yao, L., Ma, H., Zhuo, Y., Huang, H., Shi, X., Feng, L., Lin, D., Jiang, B., Li, Q.
10.1101/2023.03.23.533947 — Posted: 2023-03-23 — Discussion: 2023-09-14  eLife
The protective function of an immunity protein against the cis-toxic effects of a Xanthomonas Type IV Secretion System Effector
Oka, G., Souza, D. P., Sgro, G. G., Guzzo, C. R., Dunger, G., Farah, C. S.
10.1101/2023.08.28.555164 — Posted: 2023-08-29 — Discussion: 2023-09-12  Review Commons
Structural Basis for the Phase Separation of the Chromosome Passenger Complex
Bryan, N. W., Niedzialkowska, E., Mayne, L., Stukenberg, P. T., Black, B. E.
10.1101/2023.05.22.541822 — Posted: 2023-05-22 — Discussion: 2023-09-12  Review Commons
Syntaxin 6 delays prion protein fibril formation and prolongs presence of toxic aggregation intermediates
Sangar, D., Jack, K., Batchelor, M., Mistry, B., Bieschke, J.
10.1101/2022.08.25.505283 — Posted: 2022-08-25 — Discussion: 2023-09-06  eLife
Statin-mediated reduction in mitochondrial cholesterol primes an anti-inflammatory response in macrophages by upregulating JMJD3
Saiioum, Z., Dauner, K., Verma, N., Zhang, D. J., Nakka, K., VALDIVIESO GONZALEZ, D., Almendro-Vedia, V., McDonald, J., Lopez Montero, I., Sorisky, A., Dilworth, J., Zha, X.
10.1101/2023.01.09.523264 — Posted: 2023-01-09 — Discussion: 2023-09-06  eLife
A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance
van der Krift, F., Zijlmans, D. W., Shukla, R., Javed, A., Koukos, P. I., Schwarz, L. L. E., Timmermans-Sprang, E. P. M., Maas, P. E. M., Gahtory, D., van den Nieuwboer, M., Mol, J. A., Strous, G. J., Bonvin, A. M. J. J., Veldhuizen, E. J. A., van der Stelt, M., Weingarth, M., Vermeulen, M., Klumperman, J., Maurice, M. M.
10.1101/2023.02.26.530079 — Posted: 2023-02-27 — Discussion: 2023-09-06  EMBO Press
The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission
Paine, E. L., Skalicky, J. J., Whitby, F. G., Mackay, D. R., Ullman, K. S., Hill, C. P., Sundquist, W. I.
10.1101/2022.10.18.512775 — Posted: 2022-10-18 — Discussion: 2023-09-06  eLife

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