Channel:  Francis Crick Institute

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

1092 Articles

Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis
Pereira, C., Arroyo-Martinez, G. A., Guo, M. Z., Kelly, E. R., Grive, K. J., Mahadevaiah, S. K., Sims, J., Faca, V. M., Tsai, C., Schiltz, C. J., Wit, N., Jacobs, H., Clark, N. L., Freire, R., Turner, J., Lyndaker, A. M., Brieno-Enriquez, M. A., Cohen, P. E., Smolka, M. B., Weiss, R. S.
10.1101/2021.04.09.439198 — Posted: 2021-04-10
Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation
McClure, A. W., Diffley, J.
10.1101/2021.04.09.439171 — Posted: 2021-04-10
Image-based deep learning reveals the responses of human motor neurons to stress and ALS
Verzat, C., Harley, J., Patani, R., Luisier, R.
10.1101/2021.04.08.439054 — Posted: 2021-04-09
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of nsp5 Main Protease
Basier, C., Beale, R., Bineva-Todd, G., Canal, B., Curran, J. F., Deegan, T. D., Diffley, J. F., Fujisawa, R., Howell, M., Joshi, D., Labib, K., Lim, C. T., Milligan, J., Nagaraj, H., O'Reilly, N., Papageorgiou, G., Soudy, C., Tan, K. W., Ulferts, R., Weissmann, F., Wu, M., Zeisner, T. U.
10.1101/2021.04.07.438806 — Posted: 2021-04-08
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp13 Helicase
Beale, R., Bertolin, A. P., Borg, A., Canal, B., Diffley, J. F., Drury, L. S., Harvey, R., Howell, M., Hussain, S., Kjaer, S., McCauley, J., McCoy, L., Milligan, J., Posse, V., Roustan, C., Ulferts, R., Weissmann, F., Wu, M., Zeng, J.
10.1101/2021.04.07.438808 — Posted: 2021-04-08
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp15 Endoribonuclease
Beale, R., Bertolin, A. P., Canal, B., Deegan, T. D., Diffley, J. F., Drury, L. S., Fujisawa, R., Howell, M., Labib, K., McClure, A. W., Ulferts, R., Weissmann, F., Wu, M., Zeng, J.
10.1101/2021.04.07.438811 — Posted: 2021-04-08
Identification of SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of the nsp14 RNA Cap Methyltransferase
Basier, C., Basu, S., Beale, R., Canal, B., Cowling, V. H., Curran, J. F., Deegan, T. D., Diffley, J. F., Drury, L. S., Fujisawa, R., Howell, M., Labib, K., Lim, C. T., Mak, T., McClure, A. W., Roberts, E., Tan, K. W., Ulferts, R., Weissmann, F., Wu, M., Zeisner, T. U.
10.1101/2021.04.07.438810 — Posted: 2021-04-08
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp12/7/8 RNA-dependent RNA Polymerase
Beale, R., Bertolin, A. P., Canal, B., Diffley, J. F., Drury, L. S., Howell, M., Milligan, J., Posse, V., Ulferts, R., Weissmann, F., Wu, M., Zeng, J.
10.1101/2021.04.07.438807 — Posted: 2021-04-08
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp3 Papain-like Protease
Armstrong, L. A., Beale, R., Bineva-Todd, G., Canal, B., Diffley, J. F., Drury, L. S., Howell, M., Kulathu, Y., Labib, K., Lim, C. T., Milligan, J., O'Reilly, N., Ozono, E., Tan, K. W., Ulferts, R., Weissmann, F., Wu, M., Zeisner, T. U., Zeng, J.
10.1101/2021.04.07.438804 — Posted: 2021-04-08
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp14/nsp10 Exoribonuclease
Basier, C., Basu, S., Beale, R., Bertolin, A. P., Canal, B., Curran, J. F., Deegan, T. D., Diffley, J. F., Drury, L. S., Fujisawa, R., Howell, M., Labib, K., McClure, A. W., Milligan, J., Roberts, E., Ulferts, R., Weissmann, F., Wu, M., Zeng, J.
10.1101/2021.04.07.438812 — Posted: 2021-04-08

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