Channel:  Francis Crick Institute

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

1092 Articles

A chromatinized origin reduces the mobility of ORC and MCM through interactions and spatial constraint
Sanchez, H., Liu, Z., van Veen, E., van Laar, T., Solano, B., Diffley, J. F. X., Dekker, N. H.
10.1101/2023.05.18.541303 — Posted: 2023-06-30
Two-color coincidence single-molecule pull-down for the specific detection of disease-associated protein aggregates
Saleeb, R. S., Leighton, C., Lee, J.-E., O'Shaughnessy, J., Jeacock, K., Chappard, A., Cumberland, R., Ball, S. R., Sunde, M., Clarke, D. J., Piche, K., McPhail, J. A., Louwrier, A., Angers, R., Gandhi, S., Downey, P., Kunath, T., Horrocks, M. H.
10.1101/2023.06.27.546642 — Posted: 2023-06-29
Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen sensing pathways in mammalian cells
Tian, Y.-M., Holdship, P., To, T. Q., Ratcliffe, P. J., Keeley, T. P.
10.1101/2023.06.25.545688 — Posted: 2023-06-26
p97/VCP targets Toxoplasma gondii vacuoles for parasite restriction in interferon-stimulated human cells
Clough, B., Fisch, D., Mize, T. H., Encheva, V., Snijders, A., Frickel, E.
10.1101/2023.06.20.545566 — Posted: 2023-06-23
Abundant capped RNAs are derived from mRNA cleavage at 3'UTR G-Quadruplexes
Haberman, N., Digby, H., Faraway, R., Cheung, R., Jobbins, A. M., Parr, C., Yasuzawa, K., Kasukawa, T., Yip, C. W., Kato, M., Takahashi, H., Carninci, P., Vernia, S., Ule, J., Sibley, C. R., Martinez-Sanchez, A., Lenhard, B.
10.1101/2023.04.27.538568 — Posted: 2023-06-22
Wireless monitoring of respiration with EEG reveals relationships between respiration, behaviour and brain activity in freely moving mice
Dasgupta, D., Schneider-Luftman, D., Schaefer, A., Harris, J. J.
10.1101/2023.06.19.544346 — Posted: 2023-06-21
Dynamic X-chromosomal reactivation enhances female brain resilience
Kaeseberg, S., Bertin, M., Menon, R., Gabassi, E., Todorov, H., Frank, S., Brennenstuhl, H., Lohrer, B., Winter, J., Krummeich, J., Winkler, J., Winner, B., Weis, E., Hartwich, D., Diederich, S., Luck, K., Gerber, S., Lunt, P., Berninger, B., Falk, S., Schweiger, S., Karow, M.
10.1101/2023.06.17.545424 — Posted: 2023-06-21
The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound assembly mechanisms in ligand-free EGFR oligomers
Iyer, R. S., Needham, S. R., Galdadas, I., Davis, B. M., Roberts, S. K., Man, R. C., Zanetti-Domingues, L. C., Clarke, D. T., Fruhwirth, G. O., Parker, P. J., Rolfe, D. J., Gervasio, F. L., Martin-Fernandez, M. L.
10.1101/2023.06.16.545259 — Posted: 2023-06-20
Structure-guided design and optimization of covalent VHL-targeted sulfonyl fluoride PROTACs
Shah, R. R., De Vita, E., Conole, D., Sathyamurthi, P. S., Zhang, X., Fellows, E., Fleites, C. M., Queisser, M. A., Harling, J. D., Tate, E. W.
10.1101/2023.06.20.545773 — Posted: 2023-06-20
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology
Castano, A., Silvestre, M., Wells, C. I., Sanderson, J. L., Ferrer, C. A., Ong, H. W., Lang, Y., Richardson, W., Silvaroli, J. A., Bashore, F. M., Smith, J. L., Genereux, I. M., Dempster, K., Drewry, D. H., Pabla, N. S., Bullock, A. N., Benke, T. A., Ultanir, S., Axtman, A. D.
10.1101/2023.04.24.538049 — Posted: 2023-06-16

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