Channel:  Impact of Genomic Variation on Function (IGVF)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

106 Articles

Comparing Genomic and Epigenomic Features across Species Using the WashU Comparative Epigenome Browser
Zhuo, X., Hsu, S., Purushotham, D., Chen, S., Li, D., Wang, T.
10.1101/2022.11.29.518374 — Posted: 2022-12-02
HiCLift: A fast and efficient tool for converting chromatin interaction data between genome assemblies
Wang, X., Yue, F.
10.1101/2023.01.17.524475 — Posted: 2023-01-20
CHD-associated enhancers shape human cardiomyocyte lineage commitment
Armendariz, D. A., Goetsch, S. C., Sundarrajan, A., Sivakumar, S., Wang, Y., Xie, S., Munshi, N. V., Hon, G. C.
10.1101/2022.04.07.487515 — Posted: 2023-01-20
Dynamic network-guided CRISPRi screen reveals CTCF loop-constrained nonlinear enhancer-gene regulatory activity in cell state transitions
Luo, R., Yan, J., Oh, J. W., Xi, W., Shigaki, D., Wong, W., Cho, H., Murphy, D., Cutler, R., Rosen, B. P., Pulecio, J., Yang, D., Glenn, R., Chen, T., Li, Q. V., Vierbuchen, T., Sidoli, S., Apostolou, E., Huangfu, D., Beer, M. A.
10.1101/2023.03.07.531569 — Posted: 2023-03-09
Modeling tissue co-regulation to estimate tissue-specific contributions to disease
Amariuta, T., Siewert-Rocks, K., Price, A. L.
10.1101/2022.08.25.505354 — Posted: 2023-03-26
Orthogonal CRISPR screens to identify transcriptional and epigenetic regulators of human CD8 T cell function
McCutcheon, S., Swartz, A., Brown, M., Barrera, A., McRoberts Amador, C., Siklenka, K., Humayun, L., Isaacs, J., Reddy, T. E., Nair, S., Antonia, S., Gersbach, C. A.
10.1101/2023.05.01.538906 — Posted: 2023-05-01
A mutation rate model at the basepair resolution identifies the mutagenic effect of Polymerase III transcription
Seplyarskiy, V., Lee, D. J., Koch, E. M., Lichtman, J. S., Luan, H. H., Sunyaev, S. R.
10.1101/2022.08.20.504670 — Posted: 2023-05-17
Proximity Analysis of Native Proteomes Reveals Interactomes Predictive of Phenotypic Modifiers of Autism and Related Neurodevelopmental Conditions
Gao, Y., Trn, M., Shonai, D., Zhao, J., Soderblom, E. J., Garcia-moreno, S. A., Gersbach, C. A., Wetsel, W. C., Dawson, G., Velmeshev, D., Jiang, Y.-h., Sloofman, L. G., Buxbaum, J., Soderling, S. H.
10.1101/2022.10.06.511211 — Posted: 2023-06-23
A machine-readable specification for genomics assays
Booeshaghi, A. S., Chen, X., Pachter, L.
10.1101/2023.03.17.533215 — Posted: 2023-07-18
Transcription factor stoichiometry, motif affinity and syntax regulate single-cell chromatin dynamics during fibroblast reprogramming to pluripotency
Nair, S., Ameen, M., Sundaram, L., Pampari, A., Schreiber, J., Balsubramani, A., Wang, Y. X., Burns, D., Blau, H. M., Karakikes, I., Wang, K. C., Kundaje, A.
10.1101/2023.10.04.560808 — Posted: 2023-10-21

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