Channel:  Impact of Genomic Variation on Function (IGVF)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

106 Articles

Diverse digital and fuzzy composite transcriptional elements are prevalent features of mammalian cis-regulomes
Chaudhri, V. K., Singh, H.
10.1101/2021.11.26.470154 — Posted: 2021-11-27
Reconstructing Spatial Transcriptomics at the Single-cell Resolution with BayesDeep
Jiang, X., Dong, L., Wang, S., Wen, Z., Chen, M., Xu, L., Xiao, G., Li, Q.
10.1101/2023.12.07.570715 — Posted: 2023-12-08
MaveDB v2: a curated community database with over three million variant effects from multiplexed functional assays
Rubin, A. F., Min, J. K., Rollins, N. J., Da, E. Y., Esposito, D., Harrington, M., Stone, J., Bianchi, A. H., Dias, M., Frazer, J., Fu, Y., Gallaher, M., Li, I., Moscatelli, O., Ong, J. Y., Rollins, J. E., Wakefield, M. J., Ye, S., Tam, A., McEwen, A. E., Starita, L. M., Bryant, V. L., Marks, D. S., Fowler, D. M.
10.1101/2021.11.29.470445 — Posted: 2022-01-18
Leveraging a surrogate outcome to improve inference on a partially missing target outcome
McCaw, Z. R., Gaynor, S. M., Sun, R., Lin, X.
10.1101/2020.11.29.403063 — Posted: 2022-01-20
Exploring genomic data coupled with 3D chromatin structures using the WashU Epigenome Browser
Li, D., Purushotham, D., Harrison, J. K., Wang, T.
10.1101/2022.01.18.476849 — Posted: 2022-01-21
Enrichment of somatic mutations in schizophrenia brain targets prenatally active transcription factor bindings sites
Maury, E. A., Jones, A., Seplyarskiy, V., Rosenbluh, C., Bae, T., Wang, Y., Abyzov, A., Khoshkoo, S., Chahine, Y., Brain Somatic Mosaicism Network, , Park, P. J., Akbarian, S., Lee, E. A., Sunyaev, S. R., Walsh, C. A., Chess, A.
10.1101/2022.02.23.481681 — Posted: 2022-02-24
Heterogeneity of Inflammation-associated Synovial Fibroblasts in Rheumatoid Arthritis and Its Drivers
Smith, M. H., Gao, V. R., Schizas, M., Kochen, A., DiCarlo, E., Goodman, S., Norman, T. M., Donlin, L., Leslie, C. S., Rudensky, A. Y.
10.1101/2022.02.28.482131 — Posted: 2022-03-02
Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data
Zhang, M. J., Hou, K., Dey, K. K., Sakaue, S., Jagadeesh, K. A., Weinand, K., Taychameekiatchai, A., Rao, P., Pisco, A. O., Zou, J., Wang, B., Gandal, M., Raychaudhuri, S., Pasaniuc, B., Price, A. L.
10.1101/2021.09.24.461597 — Posted: 2022-03-04
Evolution of transposable element-derived enhancer activity
Du, A. Y., Zhuo, X., Sundaram, V., Jensen, N. O., Chaudhari, H. G., Saccone, N. L., Cohen, B. A., Wang, T.
10.1101/2022.03.16.483999 — Posted: 2022-03-17
Evidence-based calibration of computational tools for missense variant pathogenicity classification and ClinGen recommendations for clinical use of PP3/BP4 criteria
Pejaver, V., Byrne, A. B., Feng, B.-J., Pagel, K. A., Mooney, S. D., Karchin, R., O'Donnell-Luria, A., Harrison, S. M., Tavtigian, S. V., Greenblatt, M. S., Biesecker, L. G., Radivojac, P., Brenner, S. E., ClinGen Sequence Variant Interpretation Working Group
10.1101/2022.03.17.484479 — Posted: 2022-03-19

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