Channel:  Babraham Institute

154 Articles

Dynamic DNA methylation turnover at the exit of pluripotency epigenetically primes gene regulatory elements for hematopoietic lineage specification
Parry, A. J., Krueger, C., Lohoff, T., Wingett, S., Schoenfelder, S., Reik, W.
10.1101/2023.01.11.523441 — Posted: 2023-01-11
Dynamic protein deacetylation is a limited carbon source for acetyl-CoA-dependent metabolism
Soaita, I., Megill, E., Kantner, D., Chatoff, A., Arany, Z., Snyder, N. W., Wellen, K. E., Trefely, S. W.
10.1101/2022.12.28.522149 — Posted: 2022-12-29
Back to the Future: Unleashing your cytometers spectral potential
Walker, R. V., Hall, C., Ibrahim, H., Thompson, S., Hobson, P., Crofts, J.-A., Nobes, P., Lim, S., Burpee, T.
10.1101/2022.12.21.521417 — Posted: 2022-12-22
An integrated proteome and transcriptome of B cell maturation defines poised activation states of transitional and mature B cells
Salerno, F., Howden, A. J., Matheson, L. S., Gizlenci, O., Screen, M., Lingel, H., Brunner-Weinzierl, M., Turner, M.
10.1101/2022.12.22.521580 — Posted: 2022-12-22
Time-dependent regulation of cytokine production by RNA binding proteins defines T cell effector function
Popovic, B., Nicolet, B. P., Guislain, A., Engels, S., Jurgens, A. P., Paravinja, N., Freen-van Heeren, J. J., van Alphen, F. P., van den Biggelaar, M., Salerno, F., Wolkers, M. C.
10.1101/2021.11.03.467112 — Posted: 2022-12-04
Decoding gene regulation in the mouse embryo using single-cell multi-omics
Argelaguet, R., Lohoff, T., Li, J. G., Nakhuda, A., Drage, D., Krueger, F., Velten, L., Clark, S. J., Reik, W.
10.1101/2022.06.15.496239 — Posted: 2022-11-15
High-resolution promoter interaction analysis in Type 3 Innate Lymphoid Cells implicates Batten Disease gene CLN3 in Crohn's Disease aetiology
Malysheva, V., Ray-Jones, H., Cazares, T. A., Clay, O., Ohayon, D., Artemov, P., Wayman, J. A., Della Rosa, M., Petitjean, C., Booth, C., Ellaway, J. I. J., Orchard, W., Chen, X., Parameswaran, S., Nagano, T., Fraser, P., Schoenfelder, S., Weirauch, M., Kottyan, L. C., Smith, D. F., Powell, N., Weimer, J., Wallace, C., Miraldi, E. R., Waggoner, S., Spivakov, M.
10.1101/2022.10.19.512842 — Posted: 2022-11-08
Intracellular calcium elevations drive the nucleation of FIP200- and ATG13-containing pre-autophagosomal structures that become omegasomes
Smith, M., Schoenfelder, P., Manifava, M., Polson, H., Tooze, S., Roderick, L., Ktistakis, N.
10.1101/2022.11.02.514842 — Posted: 2022-11-02
FOXA2 controls the anti-oxidant response in FH-deficient cells
Rogerson, C., Sciacovelli, M., Maddalena, L. A., Valcarcel-Jimenez, L., Schmidt, C., Yang, M., Ivanova, E., Kent, J., Mora, A., Cheeseman, D., Carroll, J. S., Kelsey, G., Frezza, C.
10.1101/2022.07.04.498412 — Posted: 2022-10-14
Inter-gastruloid heterogeneity revealed by single cell transcriptomics time course: implications for organoid based perturbation studies
Rosen, L. U., Stapel, L. C., Argelaguet, R., Barker, C. G., Yang, A., Reik, W., Marioni, J. C.
10.1101/2022.09.27.509783 — Posted: 2022-09-28

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