Channel:  Babraham Institute

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

152 Articles

Phospholipase Cgamma regulates lacrimal gland branching by competing with PI3K in phosphoinositide metabolism
Wang, Q., Tao, C., Wu, Y., Anderson, K. E., Hannan, A., Lin, C.-s., Hawkins, P. T., Stephens, L., Zhang, X.
10.1101/2024.06.28.601066 — Posted: 2024-07-02
The LCLAT1/LYCAT acyltransferase is required for EGF-mediated phosphatidylinositol-3,4,5-trisphosphate generation and Akt signalling
Chan, V., Camardi, C., Zhang, K., Orofiamma, L., Anderson, K. E., Hoque, J., Bone, L., Awadeh, Y., Lee, D. K. C., Fu, N. J., Chow, J. T. S., Salmena, L., Stephens, L. R., Hawkins, P. T., Antonescu, C. N., Botelho, R. J.
10.1101/2023.01.26.524308 — Posted: 2024-06-26
A targetable PREX2/RAC1/PI3Kβ signalling axis confers resistance to clinically relevant therapeutic approaches in melanoma
Ford, C. A., Koludrovic, D., Centeno, P. P., Foth, M., Tsonou, E., Vlahov, N., Sphyris, N., Gilroy, K., Bull, C., Nixon, C., Serrels, B., Munro, A. F., Dawson, J. C., Carragher, N. O., Pavet, V., Hornigold, D. C., Dunne, P. D., Downward, J., Welch, H. C. E., Barry, S. T., Sansom, O. J., Campbell, A. D.
10.1101/2024.02.26.580534 — Posted: 2024-02-28
Tissue-resident regulatory T cells exert dualistic anti-tumour and pro-repair function in the exocrine pancreas
Stockis, J., Yip, T., Raghunathan, S., Garcia, C., Lee, S., Simpson, C., Silvain, S., Schuijs, M. J., Araos, J., Png, S., Raddi, G., Bricard, O., So, T. Y., Mack, S., Papadopoulos, P., Sawle, A., Jodrell, D. I., McKenzie, A. N. J., Thaventhiran, J., Clatworthy, M., Biffi, G., Saeb-Parsy, K., Liston, A., Halim, T. Y. F.
10.1101/2024.02.15.580302 — Posted: 2024-02-19
Regulation of IFNgamma production by ZFP36L2 in T cells is context-dependent
Zandhuis, N. D., Guislain, A., Popalzij, A., Engels, S., Popovic, B., Turner, M., Wolkers, M. C.
10.1101/2024.02.09.579641 — Posted: 2024-02-12
Single-cell analysis reveals lasting immunological consequences of influenza infection and respiratory immunisation in the pig lung
Muir, A., Paudyal, B., Schmidt, S., Sedaghat-Rostani, E., Chakravarti, S., Villanueva Hernandez, S., Moffat, K., Polo, N., Angelopoulos, N., Schmidt, A., Tenbusch, M., Freimanis, G., Gerner, W., Richard, A. C., Tchilian, E.
10.1101/2023.12.19.572318 — Posted: 2023-12-19
Protein tyrosine phosphatase receptor kappa regulates glycolysis and de novo lipogenesis to promote hepatocyte metabolic reprogramming in obesity
Gilglioni, E. H., Li, A., Saint-Pierre Wijckmans, W., Shen, T.-K., Perez-Chavez, I., Hovhannisyan, G., Lisjak, M., Negueruela, J., Vandenbempt, V., Bauza-Martinez, J., Herranz, J. M., Ezerina, D., Demine, S., Feng, Z., Vignane, T., Otero-Sanchez, L., Lambertucci, F., Prasnicka, A., Deviere, J., Hay, D. C., Encinar, J. A. N., Singh, S. P., Messens, J., Filipovic, M. R., Sharpe, H. J., Trepo, E., Wu, W., Gurzov, E. N.
10.1101/2023.12.01.569004 — Posted: 2023-12-01
Ageing impairs the regenerative capacity of regulatory T cells in central nervous system remyelination
de la Fuente, A. G., Dittmer, M., Heesbeen, E., de la Vega-Gallardo, N., White, J. A., Young, A., McColgan, T., Dashwood, A., Mayne, K., Cabeza-Fernandez, S., Falconer, J., Rodriguez-Baena, F. J., McMurran, C. E., Innayatulah, M., Rawji, K. S., Franklin, R. J., Dooley, J., Liston, A., Ingram, R. J., Tiwari, V. K., Penalva, R., Dombrowski, Y., Fitzgerald, D. C.
10.1101/2023.01.25.525562 — Posted: 2023-11-26
Epi-microRNA mediated metabolic reprogramming ensures affinity maturation
Nakagawa, R., Llorian, M., Varsani-brown, S., Chakravarty, P., Camarillo, J. M., Barry, D., George, R., Blackledge, N. P., Duddy, G., Kelleher, N. L., Klose, R. J., Turner, M., Calado, D. P.
10.1101/2023.07.31.551250 — Posted: 2023-10-31
The N-terminal region of DNMT3A combines multiple chromatin reading motifs to guide recruitment.
Wapenaar, H., Clifford, G., Rolls, W., Burdett, H., Zhang, Y., Deak, G., Zou, J., Taylor, M. R., Mills, J., Watson, J. A., Kumar, D., Das, A., Valsakumar, D., Bramham, J., Voigt, P., Wilson, M. D.
10.1101/2023.10.29.564595 — Posted: 2023-10-29

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