Channel:  Harvard Program in Therapeutic Sciences

114 Articles

ASCT2 is the primary serine transporter in cancer cells
Conger, K. O., Chidley, C., Ozgurses, M. E., Zhao, H., Kim, Y., Semina, S. E., Burns, P. A., Rawat, V., Sheldon, R., Ben-Sahra, I., Frasor, J., Sorger, P. K., DeNicola, G. M., Coloff, J. L.
10.1101/2023.10.09.561530 — Posted: 2023-10-11
Resident memory T cell development is associated with AP-1 transcription factor upregulation across anatomical niches.
Smith, N. P., Yan, Y., Pan, Y., Williams, J. B., Manakongtreecheep, K., Pant, S., Zhao, J., Tian, T., Pan, T., Stingley, C., Wu, K., Zhang, J., Kley, A. L., Sorger, P. K., Villani, A.-C., Kupper, T. S.
10.1101/2023.09.29.560006 — Posted: 2023-10-02
OpenFold: Retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization
Ahdritz, G., Bouatta, N., Floristean, C., Kadyan, S., Xia, Q., Gerecke, W., O'Donnell, T. J., Berenberg, D., Fisk, I., Zanichelli, N., Zhang, B., Nowaczynski, A., Wang, B., Stepniewska-Dziubinska, M. M., Zhang, S., Ojewole, A., Guney, M. E., Biderman, S., Watkins, A. M., Ra, S., Lorenzo, P. R., Nivon, L., Weitzner, B., Ban, Y.-E. A., Sorger, P. K., Mostaque, E., Zhang, Z., Bonneau, R., AlQuraishi, M.
10.1101/2022.11.20.517210 — Posted: 2023-08-12
Addressing persistent challenges in digital image analysis of cancerous tissues
Prabhakaran, S., Yapp, C., Baker, G. J., Beyer, J., Chang, Y. H., Creason, A. L., Krueger, R., Muhlich, J., Patterson, N. H., Sidak, K., Sudar, D., Taylor, A. J., Ternes, L., Troidl, J., Yubin, X., Sokolov, A., Tyson, D. R., Participants of the Cell Imaging Hackathon 2022
10.1101/2023.07.21.548450 — Posted: 2023-07-24
Immune Profiling of Dermatologic Adverse Events from Checkpoint Blockade using Tissue Cyclic Immunofluorescence
Maliga, Z., Kim, D. Y., Bui, A.-T. N., Lin, J.-R., Dewan, A. K., Murphy, G. F., Nirmal, A. J., Lian, C. G., Sorger, P. K., LeBoeuf, N. R.
10.1101/2023.04.03.535435 — Posted: 2023-04-05
Matrix and analysis metadata standards (MAMS) to facilitate harmonization and reproducibility of single-cell data
Wang, Y., Sarfraz, I., Teh, W. K., Sokolov, A., Herb, B. R., Creasy, H. H., Virshup, I., Dries, R., Degatano, K., Mahurkar, A., Schnell, D. J., Madrigal, P., Hilton, J., Gehlenborg, N., Tickle, T., Campbell, J. D.
10.1101/2023.03.06.531314 — Posted: 2023-03-07
Parallel evolution of mutational fitness effects over 50,000 generations
Limdi, A., Owen, S. V., Herren, C., Lenski, R. E., Baym, M.
10.1101/2022.05.17.492023 — Posted: 2023-03-07
Multi-modal digital pathology for colorectal cancer diagnosis by high-plex immunofluorescence imaging and traditional histology of the same tissue section
Lin, J.-R., Chen, Y.-A., Campton, D., Cooper, J., Coy, S., Yapp, C., Tefft, J., McCarty, E., Ligon, K., Rodig, S. J., Reese, S., George, T., Santagata, S., Sorger, P. K.
10.1101/2022.09.28.509927 — Posted: 2023-02-21
Nociceptor neuroimmune interactomes reveal cell type- and injury-specific inflammatory pain pathways
Jain, A., Gyori, B., Hakim, S., Bunga, S., Taub, D. G., Ruiz-Cantero, M. C., Tong-Li, C., Andrews, N., Sorger, P. K., Woolf, C. J.
10.1101/2023.02.01.526526 — Posted: 2023-02-03
A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments
Chidley, C., Darnell, A. M., Gaudio, B. L., Lien, E. C., Barbeau, A. M., Vander Heiden, M. G., Sorger, P. K.
10.1101/2023.01.26.525375 — Posted: 2023-01-26

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