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541 Reviews — All Partners — Biochemistry

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An Atlas of Phosphorylation and Proteolytic Processing Events During Excitotoxic Neuronal Death Reveals New Therapeutic Opportunities
Ameen, S. S., Dufour, A., Hossain, M. I., Hoque, A., Sturgeon, S., Nandurkar, H., Draxler, D., Medcalf, R., Kamaruddin, M. A., Lucet, I., Leeming, M., Liu, D., Dhillon, A., Lim, J. P., Zhu, H., Bokhari, L., Roulston, C., Kleifeld, O., Ciccotosto, G., Williamson, N. A., Ang, C.-S., Cheng, H. C.
10.1101/2020.06.15.151456 — Posted: 2020-06-15 — Discussion: 2020-09-15  Review Commons
More than just a ticket canceller: The mitochondrial processing peptidase matures complex precursor proteins at internal cleavage sites
Friedl, J., Knopp, M. R., Groh, C., Paz, E., Gould, S. B., Boos, F., Herrmann, J. M.
10.1101/2020.07.02.183996 — Posted: 2020-07-03 — Discussion: 2020-09-08  eLife
The crystal structure of the Ca2+-ATPase 1 from Listeria monocytogenes reveals a pump primed for dephosphorylation
Basse Hansen, S., Dyla, M., Neumann, C. M. T., Lauwring Andersen, J., Kjaergaard, M., Nissen, P.
10.1101/2020.06.23.166462 — Posted: 2020-06-23 — Discussion: 2020-09-01  eLife
The half-life of the bone-derived hormone osteocalcin is regulated through O-glycosylation in mice, but not in humans
Al Rifai, O., Julien, C., Faubert, D., Lira-Navarrete, E., Narimatsu, Y., Lacombe, J., Clausen, H., Ferron, M.
10.1101/2020.07.16.206656 — Posted: 2020-07-16 — Discussion: 2020-08-24  eLife
Optogenetic activation of heterotrimeric Gi proteins by LOV2GIVe - a rationally engineered modular protein
Garcia-Marcos, M., Parag-Sharma, K., Marivin, A., Maziarz, M., Luebbers, A., Nguyen, L. T.
10.1101/2020.08.17.253781 — Posted: 2020-08-19 — Discussion: 2020-08-20  eLife
Exosite inhibition of A Disintegrin And Metalloproteinase with Thrombospondin motif (ADAMTS)-5 by a glycoconjugated arylsulfonamide
Santamaria, S., Cuffaro, D., Nuti, E., Ciccone, L., Tuccinardi, T., Liva, F., D'Andrea, F., de Groot, R., Rossello, A., Ahnstroem, J.
10.1101/2020.06.12.146324 — Posted: 2020-06-12 — Discussion: 2020-07-24  eLife
A giant leap in sequence space reveals the intracellular complexities of evolving a new function
Hall, K. R., Robins, K. J., Rich, M. H., Calcott, M. J., Copp, J., Williams, E. M., Little, R. F., Schwörer, R., Evans, G. B., Patrick, W. M., Ackerley, D. F.
10.1101/2020.05.27.118489 — Posted: 2020-05-30 — Discussion: 2020-07-20  eLife
Identification and characterization of diverse OTU deubiquitinases in bacteria
Schubert, A. F., Nguyen, J. V., Franklin, T. G., Geurink, P. P., Roberts, C. G., Sanderson, D. J., Miller, L. N., Ovaa, H., Hofmann, K., Pruneda, J. N., Komander, D.
10.1101/2020.03.28.013474 — Posted: 2020-03-29 — Discussion: 2020-07-15  EMBO Press
Characterisation of the c10orf76-PI4KB complex, and its necessity for Golgi PI4P levels and enterovirus replication
McPhail, J. A., Lyoo, H., Pemberton, J. G., Hoffmann, R. M., van Elst, W., Strating, J. R. P. M., Jenkins, M. L., Stariha, J., van Kuppeveld, F. J. M., Balla, T., Burke, J. E.
10.1101/634592 — Posted: 2019-05-10 — Discussion: 2020-07-15  EMBO Press
Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts
Tesina, P., Lessen, L. N., Buschauer, R., Cheng, J., Wu, C. C.-C., Berninghausen, O., Buskirk, A. R., Becker, T., Beckmann, R., Green, R.
10.1101/755652 — Posted: 2019-09-04 — Discussion: 2020-07-15  EMBO Press

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