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540 Reviews — All Partners — Biochemistry

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Acyl chain shortening induced by inhibition of acetyl-CoA carboxylase renders phosphatidylcholine redundant
Bao, X., Koorengevel, M. C., Groot Koerkamp, M. J. A., Homavar, A., Weijn, A., Crielaard, S., Renne, M. F., Geerts, W. J. C., Surma, M. A., Mari, M., Holstege, F. C. P., Klose, C., de Kroon, A. I. P. M.
10.1101/2021.02.08.429707 — Posted: 2021-02-08 — Discussion: 2021-11-13  EMBO Press
Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism
Ryan, D. G., Yang, M., Prag, H. A., Blanco, G. R., Nikitopoulou, E., Segarra-Mondejar, M., Powell, C. A., Young, T., Burger, N., Miljkovic, J. L., Minczuk, M., Murphy, M. P., Von Kriegsheim, A., Frezza, C.
10.1101/2021.07.27.453996 — Posted: 2021-07-27 — Discussion: 2021-11-04  eLife
Disintegration promotes proto-spacer integration by the Cas1-Cas2 complex
Ma, C.-H., Javanmardi, K., Finkelstein, I. J., Jayaram, M.
10.1101/2020.12.21.423798 — Posted: 2020-12-21 — Discussion: 2021-11-03  eLife
Quantitative Proteomics Identifies PTP1B as Modulator of B Cell Antigen Receptor Signaling
Schwarz, J., Grundmann, L., Kokot, T., Kläsener, K. A., Fotteler, S., Medgyesi, D., Koehn, M., Reth, M., Warscheid, B.
10.1101/2021.03.30.437652 — Posted: 2021-04-02 — Discussion: 2021-11-02  EMBO Press
Structural basis for the specificity of PPM1H phosphatase for Rab GTPases
Waschbüsch, D., Berndsen, K., Knebel, A., Alessi, D. R., Khan, A. R.
10.1101/2021.02.17.431620 — Posted: 2021-02-17 — Discussion: 2021-11-02  EMBO Press
Cryo-EM Structures of CTP Synthase Filaments Reveal Mechanism of pH-Sensitive Assembly During Budding Yeast Starvation
Hansen, J. M., Horowitz, A., Lynch, E. M., Farrell, D. P., Quispe, J., DiMaio, F., Kollman, J. M.
10.1101/2021.08.25.457724 — Posted: 2021-08-26 — Discussion: 2021-11-01  eLife
Assessing target engagement using proteome-wide solvent shift assays
Van Vranken, J. G., Li, J., Navarrete Perea, J., Gygi, S. P.
10.1101/2021.07.22.453338 — Posted: 2021-07-22 — Discussion: 2021-10-28  eLife
Allosteric cooperation in β-lactam binding to a non-classical transpeptidase
Ahmad, N., Kachhap, S., Chauhan, V., Juneja, P., Sharma, K., Bullen, C. K., Borowski, T., Bishai, W. R., Lamichhane, G., Kumar, P.
10.1101/2021.09.06.459080 — Posted: 2021-09-06 — Discussion: 2021-10-28  eLife
Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2
Mast, F. D., Fridy, P. C., Ketaren, N. E., Wang, J., Jacobs, E. Y., Olivier, J. P., Sanyal, T., Molloy, K. R., Schmidt, F., Rutkowska, M., Weisblum, Y., Rich, L. M., Vanderwall, E. R., Dambrauskas, N., Vigdorovich, V., Keegan, S., Jiler, J. B., Stein, M. E., Olinares, P. D. B., Hatziioannou, T., Sather, D. N., Debley, J. S., Fenyö, D., Sali, A., Bieniasz, P. D., Aitchison, J. D., Chait, B. T., Rout, M. P.
10.1101/2021.04.08.438911 — Posted: 2021-04-10 — Discussion: 2021-10-27  eLife
Branched ubiquitin chain binding and deubiquitination by UCH37 facilitate proteasome clearance of stress-induced inclusions
Song, A., Hazlett, Z., Abeykoon, D., Dortch, J., Dillon, A., Curtiss, J., Martinez, S. B., Hill, C. P., Yu, C., Huang, L., Fushman, D., Cohen, R. E., Yao, T.
10.1101/2021.08.17.456719 — Posted: 2021-08-17 — Discussion: 2021-10-22  eLife

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