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372 Reviews — eLife — Biochemistry

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Structure-guided microbial targeting of antistaphylococcal prodrugs
Miller, J., Shah, I. T., Hatten, J., Barekatain, Y., Mueller, E. A., Moustafa, A. M., Edwards, R. L., Dowd, C. S., Planet, P. J., Muller, F. L., Jez, J. M., Odom John, A. R.
10.1101/2020.12.15.408237 — Posted: 2020-12-15 — Discussion: 2021-06-29  eLife
Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace
Williams, R. L., Heimhalt, M., Berndt, A., Wagstaff, J. L., Anandapadamanaban, M., Perisic, O., Maslen, S., McLaughlin, S. H., Yu, C. W.-H., Masson, G. R., Boland, A., Ni, X., Yamashita, K., Murshudov, G. N., Skehel, M., Freund, S. M.
10.1101/2021.04.28.441853 — Posted: 2021-04-30 — Discussion: 2021-06-22  eLife
Tissue specific targeting of DNA nanodevices in a multicellular living organism
Krishnan, Y., Chakraborty, K., Surana, S., Martin, S., Aburas, J., Moutel, S., Perez, F., Koushika, S. P., Kratsios, P.
10.1101/2021.03.05.434169 — Posted: 2021-03-06 — Discussion: 2021-06-16  eLife
Structure and mechanistic features of the prokaryotic minimal RNase P
Feyh, R., Waeber, N. B., Prinz, S., Giammarinaro, P. I., Bange, G., Hochberg, G., Hartmann, R. K., Altegoer, F.
10.1101/2021.05.07.443126 — Posted: 2021-05-07 — Discussion: 2021-06-10  eLife
MBNL1 and RBFOX1 co-regulate alternative splicing events transcriptome-wide through a conserved buffering mechanism
Berglund, J. A., Hale, M., Ellis, J. A., Meng, R., McDaniel, S., Mahady, A., Wagner, S., Richardson, J., McConnell, O., T. Wang, E.
10.1101/2021.04.20.440659 — Posted: 2021-04-20 — Discussion: 2021-06-03  eLife
Assembly of higher-order SMN oligomers is essential for metazoan viability and requires an exposed structural motif present in the YG zipper dimer
Gupta, K., Wen, Y., Ninan, N. S., Raimer, A. C., Sharp, R., Spring, A. M., Sarachan, K. L., Johnson, M. C., Van Duyne, G. D., Matera, A. G.
10.1101/2020.11.07.336172 — Posted: 2020-11-08 — Discussion: 2021-06-03  eLife
Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops.
Urrutia, I., Ault, J., Sobott, F., Savery, N., Dillingham, M. S.
10.1101/2021.03.15.435481 — Posted: 2021-03-15 — Discussion: 2021-06-03  eLife
Cooperation among c-subunits of FoF1-ATP synthase in rotation-coupled proton translocation
Mitome, N., Kubo, S., Ohta, S., Takashima, H., Shigefuji, Y., Niina, T., Takada, S.
10.1101/2021.03.25.436961 — Posted: 2021-03-25 — Discussion: 2021-06-02  eLife
AKAP79 enables calcineurin to directly suppress protein kinase A activity
Church, T. W., Tewatia, P., Hannan, S., Antunes, J., Eriksson, O., Smart, T. G., Hellgren Kotaleski, J., Gold, M.
10.1101/2021.03.14.435320 — Posted: 2021-03-15 — Discussion: 2021-05-13  eLife
Permeant Fluorescent Probes Visualize the Activation of SARM1 and Uncover an Anti-neurodegenerative Drug Candidate
Li, W. H., Huang, K., Cai, Y., Wang, Q. W., Zhu, W. J., Hou, Y. N., Wang, S., Cao, S., Zhao, Z. Y., Xie, X. J., Du, Y., Lee, C., Lee, H. C., Zhang, H., Zhao, Y. J.
10.1101/2021.02.24.432704 — Posted: 2021-02-25 — Discussion: 2021-05-10  eLife

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