bioRxiv/medRxiv TRiP Review Activity

542 Reviews — All Partners — Biochemistry

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High-throughput proteomics of nanogram-scale samples with Zeno SWATH DIA

Wang, Z., Muelleder, M., Batruch, I., Chelur, A., Textoris-Taube, K., Schwecke, T., Hartl, J., Causon, J., Castro-Perez, J., Demichev, V., Tate, S., Ralser, M.

10.1101/2022.04.14.488299 — Posted: 2022-04-14 — Discussion: 2022-09-23 Review Commons

A novel fold for acyltransferase-3 (AT3) proteins provides a framework for transmembrane acyl-group transfer

Newman, K. E., Tindall, S. N., Mader, S. L., Khalid, S., Thomas, G. H., Van der Woude, M. W.

10.1101/2022.06.30.498268 — Posted: 2022-06-30 — Discussion: 2022-09-23 eLife

Hypoxia causes pancreatic β-cell dysfunction by activating a transcriptional repressor BHLHE40

Tsuyama, T., Sato, Y., Yoshizawa, T., Matsuoka, T., Yamagata, K.

10.1101/2022.06.28.498031 — Posted: 2022-06-29 — Discussion: 2022-09-23 Review Commons

A Feed-forward Pathway Drives LRRK2 kinaseMembrane Recruitment and Apparent Activation

Vides, E. G., Adhikari, A., Lis, P., Purlyte, E., Shumate, J. L., Lasso, E. S., Dhekne, H. S., Alessi, D. R., Pfeffer, S. R.

10.1101/2022.04.25.489459 — Posted: 2022-04-25 — Discussion: 2022-09-22 eLife

Hepatic AMPK activation in response to dynamic REDOX balance is a biomarker of exercise to improve blood glucose control

Wu, M., Zhao, A., Yan, X., Gao, H., Zhang, C., Liu, X., Luo, Q., Xie, F., Liu, S., Shi, D.

10.1101/2022.05.15.491995 — Posted: 2022-05-15 — Discussion: 2022-09-16 eLife

Deep mutational scanning and machine learning reveal structural and molecular rules governing allosteric hotspots in homologous proteins

Leander, M., Liu, Z., Cui, Q., Raman, S.

10.1101/2022.05.01.490188 — Posted: 2022-05-01 — Discussion: 2022-09-02 eLife

DNA passes through cohesin's hinge as well as its Smc3-kleisin interface

Nasmyth, K. A., Collier, J. E.

10.1101/2022.05.30.494034 — Posted: 2022-05-30 — Discussion: 2022-08-27 eLife

Ligand-induced shifts in conformational ensembles that predict transcriptional activation

Khan, S. H., Braet, S. M., Koehler, S. J., Elacqua, E., Anand, G. S., Okafor, C. D.

10.1101/2022.05.29.493907 — Posted: 2022-05-29 — Discussion: 2022-08-27 eLife

Nuclear import and chaperoning of monomeric histones H3 and H4 is mediated by Imp5, NASP and the HAT1 complex

Pardal, A. J., Bowman, A. J.

10.1101/2021.10.19.464968 — Posted: 2021-10-20 — Discussion: 2022-08-25 eLife

Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3' end biogenesis

Muckenfuss, L. M., Migenda Herranz, A. C., Boneberg, F. M., Clerici, M., Jinek, M.

10.1101/2022.05.31.494127 — Posted: 2022-05-31 — Discussion: 2022-08-23 eLife