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514 Reviews — All Partners — Biophysics

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Conserved allosteric inhibition mechanism in SLC1 transporters
Dong, Y., Wang, J., Garibsingh, R.-A., Hutchinson, K., Shi, Y., Eisenberg, G., Yu, X., Schlessinger, A., Grewer, C.
10.1101/2022.09.21.508810 — Posted: 2022-09-22 — Discussion: 2023-01-30  eLife
Timeline of changes in spike conformational dynamics in emergent SARS-CoV-2 variants reveal progressive stabilization of trimer stalk and enhanced NTD dynamics
Braet, S. M., Buckley, T. S., Venkatakrishnan, V., Dam, K.-M. A., Bjorkman, P. J., Anand, G. S.
10.1101/2022.08.26.505369 — Posted: 2022-08-29 — Discussion: 2023-01-26  eLife
A canonical chaperone and a heat-resistant obscure (Hero) protein mediate similar conformational modulation and aggregation suppression of TDP-43
Lam, A. Y. W., Tsuboyama, K., Tadakuma, H., Tomari, Y.
10.1101/2022.11.15.516569 — Posted: 2022-11-15 — Discussion: 2023-01-24  Review Commons
Gating interactions steer loop conformational changes in the active site of the L1 metallo-β-lactamase
Zhao, Z., Shen, X., Chen, S., Gu, J., Wang, H., Mojica, M. F., Samanta, M., Bhowmik, D., Vila, A. J., Bonomo, R. A., Haider, S.
10.1101/2022.10.25.513716 — Posted: 2022-10-27 — Discussion: 2023-01-19  eLife
The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins
Miller, A. N., Houlihan, P. R., Matamala, E., Cabezas-Bratesco, D., Lee, G. Y., Cristofori-Armstrong, B., Dilan, T. L., Sanchez-Martinez, S., Matthies, D., Yan, R., Yu, Z., Ren, D., Brauchi, S. E., Clapham, D. E.
10.1101/2022.09.02.506428 — Posted: 2022-09-03 — Discussion: 2023-01-10  eLife
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains
Meller, A., Lotthammer, J. M., Smith, L. G., Novak, B., Lee, L. A., Kuhn, C. C., Greenberg, L., Leinwand, L. A., Greenberg, M. J., Bowman, G. R.
10.1101/2022.09.05.506254 — Posted: 2022-09-05 — Discussion: 2023-01-09  eLife
Voltage clamp fluorometry analysis of the P2X7 receptor suggests a limited conformational interplay between extracellular ATP binding and the intracellular ballast domain
Durner, A., Durner, E., Nicke, A.
10.1101/2022.08.31.506013 — Posted: 2022-09-01 — Discussion: 2023-01-02  eLife
Chloride ion evokes taste sensation by binding to the extracellular ligand-binding domain of sweet/umami taste receptors
Atsumi, N., Yasumatsu, K., Takashina, Y., Ito, C., Yasui, N., Yamashita, A.
10.1101/2022.02.23.481615 — Posted: 2022-02-24 — Discussion: 2022-12-29  eLife
Activation-pathway transitions in human voltage-gated proton channels revealed by a non-canonical fluorescent amino acid.
Suarez-Delgado, E., Rangel-Yescas, G. E., Islas, L. D.
10.1101/2022.06.30.498345 — Posted: 2022-07-01 — Discussion: 2022-12-23  Biophysics Colab
Motor processivity and speed determine structure and dynamics of microtubule-motor assemblies
Banks, R. A., Galstyan, V., Lee, H. J., Hirokawa, S., Ierokomos, A., Ross, T. D., Bryant, Z., Thomson, M., Phillips, R.
10.1101/2021.10.22.465381 — Posted: 2021-10-23 — Discussion: 2022-12-21  eLife

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