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509 Reviews — All Partners — Biophysics

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Cryo-EM structure of the octameric pore of Clostridium perfringens β-toxin
Bruggisser, J., Iacovache, I., Musson, S. C., Degiacomi, M. T., Posthaus, H., Zuber, B.
10.1101/2021.11.23.469684 — Posted: 2021-11-23 — Discussion: 2023-02-17  EMBO Press
Conformational and oligomeric states of SPOP from small-angle X-ray scattering and molecular dynamics simulations
Thomasen, F. E., Cuneo, M. J., Mittag, T., Lindorff-Larsen, K.
10.1101/2022.10.08.511432 — Posted: 2022-10-08 — Discussion: 2023-02-15  eLife
Cell size scaling laws: a unified theory
Rollin, R., Joanny, J.-F., Sens, P.
10.1101/2022.08.01.502021 — Posted: 2022-08-03 — Discussion: 2023-02-10  eLife
PAR recognition by multiple reader domains of PARP1 allosterically regulates the DNA-dependent activities and independently stimulates the catalytic activity of PARP1
Deeksha, W., Abhishek, S., Rajakumara, E.
10.1101/2021.12.21.473685 — Posted: 2021-12-22 — Discussion: 2023-02-07  Review Commons
Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B
Mehlman, T. S., Biel, J. T., Azeem, S. M., Nelson, E. R., Hossain, S., Dunnett, L. E., Paterson, N. G., Douangamath, A., Talon, R., Axford, D., Orins, H., von Delft, F., Keedy, D. A.
10.1101/2022.11.02.514751 — Posted: 2022-11-03 — Discussion: 2023-01-31  eLife
Conserved allosteric inhibition mechanism in SLC1 transporters
Dong, Y., Wang, J., Garibsingh, R.-A., Hutchinson, K., Shi, Y., Eisenberg, G., Yu, X., Schlessinger, A., Grewer, C.
10.1101/2022.09.21.508810 — Posted: 2022-09-22 — Discussion: 2023-01-30  eLife
Timeline of changes in spike conformational dynamics in emergent SARS-CoV-2 variants reveal progressive stabilization of trimer stalk and enhanced NTD dynamics
Braet, S. M., Buckley, T. S., Venkatakrishnan, V., Dam, K.-M. A., Bjorkman, P. J., Anand, G. S.
10.1101/2022.08.26.505369 — Posted: 2022-08-29 — Discussion: 2023-01-26  eLife
A canonical chaperone and a heat-resistant obscure (Hero) protein mediate similar conformational modulation and aggregation suppression of TDP-43
Lam, A. Y. W., Tsuboyama, K., Tadakuma, H., Tomari, Y.
10.1101/2022.11.15.516569 — Posted: 2022-11-15 — Discussion: 2023-01-24  Review Commons
Gating interactions steer loop conformational changes in the active site of the L1 metallo-β-lactamase
Zhao, Z., Shen, X., Chen, S., Gu, J., Wang, H., Mojica, M. F., Samanta, M., Bhowmik, D., Vila, A. J., Bonomo, R. A., Haider, S.
10.1101/2022.10.25.513716 — Posted: 2022-10-27 — Discussion: 2023-01-19  eLife
The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins
Miller, A. N., Houlihan, P. R., Matamala, E., Cabezas-Bratesco, D., Lee, G. Y., Cristofori-Armstrong, B., Dilan, T. L., Sanchez-Martinez, S., Matthies, D., Yan, R., Yu, Z., Ren, D., Brauchi, S. E., Clapham, D. E.
10.1101/2022.09.02.506428 — Posted: 2022-09-03 — Discussion: 2023-01-10  eLife

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