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222 Reviews — eLife — Genetics

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Integrating bulk and single cell RNA-seq refines transcriptomic profiles of specific C. elegans neurons.
Barrett, A., Varol, E., Weinreb, A., Taylor, S. R., McWhirter, R., Cros, C., Basavaraju, M., Poff, A., Tipps, J. A., Majeed, M., Vidal, B., Wang, C., Yemini, E., Bayer, E. A., Sun, H., Hobert, O., Miller, D. M., Hammarlund, M.
10.1101/2022.04.05.487209 — Posted: 2022-04-08 — Discussion: 2025-12-29  eLife
Microbiota/gut/neuron axis promotes Drosophila ageing via Acetobacter, Tachykinin, and TkR99D
Marcu, D., Sannino, D., Dornan, A., Ibrahim, R., Kapoor, A., Wood, M., Dobson, A. J.
10.1101/2025.07.31.667994 — Posted: 2025-08-02 — Discussion: 2025-12-10  eLife
Opiate responses are controlled by interactions of Oprm1 and Fgf12 loci in the murine BXD family: Correspondence to human GWAS finding
Lemen, P. M., Hatoum, A. S., Dickson, P. E., Mittleman, G., Agrawal, A., Reiner, B. C., Berrettini, W., Ashbrook, D. G., Gunturkun, H., Mulligan, M. K., Williams, R. W., Chen, H.
10.1101/2022.03.11.483993 — Posted: 2022-03-12 — Discussion: 2025-11-13  eLife
Redox Dyshomeostasis Links Renal and Neuronal Dysfunction in Drosophila Models of Gaucher and Parkinson's Disease
Hull, A. J., Atilano, M. L., Kinghorn, K. J.
10.1101/2025.08.06.668868 — Posted: 2025-08-09 — Discussion: 2025-10-30  eLife
Abundant Parent-of-origin Effect eQTL in Humans: The Framingham Heart Study
Guan, Y., Levy, D.
10.1101/2024.06.05.597677 — Posted: 2024-06-10 — Discussion: 2025-10-20  eLife
BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD
Tran, U., Streets, A. J., Smith, D., Decker, E., Kirschfink, A., Izem, L., Hassey, J., Ruthland, B., Valluru, M. K., Bräsen, J. H., Ott, E., Epting, D., Eisenberger, T., Ong, A. C., Bergmann, C., Wessely, O.
10.1101/2024.08.27.608867 — Posted: 2024-08-27 — Discussion: 2025-10-16  eLife
Independent Validation of Transgenerational Inheritance of Learned Pathogen Avoidance in Caenorhabditis elegans
Akinosho, A., Alexander, J., Floyd, K., Vidal-Gadea, A.
10.1101/2025.04.03.647070 — Posted: 2025-04-08 — Discussion: 2025-10-10  eLife
Decapping activators Edc3 and Scd6 act redundantly with Dhh1 in post-transcriptional repression of starvation-induced pathways
Kumar, R., Zhang, F., Niphadkar, S., Onu, C., Vijjamarri, A. K., Greenberg, M. L., Laxman, S., Hinnebusch, A. G.
10.1101/2024.08.28.610059 — Posted: 2024-08-28 — Discussion: 2025-10-09  eLife
Mapping of in vivo cleavage sites uncovers a major role for yeast RNase III in regulating protein-coding genes
Notice-Sarpaning, L.-A., Catala, M., Elela, S. A., Van Hoof, A.
10.1101/2025.03.07.642061 — Posted: 2025-03-11 — Discussion: 2025-10-01  eLife
Identifying the genetic basis and molecular mechanisms underlying phenotypic correlation between complex human traits using a gene-based approach
Gu, J., Fuller, C. K., Zheng, J., Li, H.
10.1101/2021.02.09.430368 — Posted: 2021-02-10 — Discussion: 2025-09-16  eLife

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