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348 Reviews — eLife — Biochemistry

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Coiled coil control of diverse EGFR functions
Mozumdar, D., Quach, K., Doerner, A., Schepartz, A.
10.1101/2020.12.10.419739 — Posted: 2020-12-11 — Discussion: 2021-12-02  eLife
A structural mechanism for the generation of biased agonism in the epidermal growth factor receptor
Huang, Y., Ognjenovic, J., Karandur, D., Merk, A., Subramaniam, S., Kuriyan, J.
10.1101/2020.12.08.417006 — Posted: 2020-12-09 — Discussion: 2021-11-23  eLife
Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor
Capraz, T., Kienzl, N. F., Laurent, E., Perthold, J. W., Foederl-Hoebenreich, E., Gruenwald-Gruber, C., Maresch, D., Monteil, V., Niederhoefer, J., Wirnsberger, G., Mirazimi, A., Zatloukal, K., Mach, L., Penninger, J. M., Oostenbrink, C., Stadlmann, J.
10.1101/2021.08.31.458325 — Posted: 2021-08-31 — Discussion: 2021-11-18  eLife
Allosteric mechanism of signal transduction in the two-component system histidine kinase PhoQ
Mensa, B., Polizzi, N. F., Molnar, K. S., Natale, A. M., Lemmin, T., DeGrado, W. F.
10.1101/2021.09.03.458835 — Posted: 2021-09-05 — Discussion: 2021-11-18  eLife
Heavy isotope labeling and mass spectrometry reveal unexpected remodeling of bacterial cell wall expansion in response to drugs
Atze, H., Rusconi, F., Arthur, M.
10.1101/2021.08.06.454924 — Posted: 2021-08-06 — Discussion: 2021-11-17  eLife
Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism
Ryan, D. G., Yang, M., Prag, H. A., Blanco, G. R., Nikitopoulou, E., Segarra-Mondejar, M., Powell, C. A., Young, T., Burger, N., Miljkovic, J. L., Minczuk, M., Murphy, M. P., Von Kriegsheim, A., Frezza, C.
10.1101/2021.07.27.453996 — Posted: 2021-07-27 — Discussion: 2021-11-04  eLife
Disintegration promotes proto-spacer integration by the Cas1-Cas2 complex
Ma, C.-H., Javanmardi, K., Finkelstein, I. J., Jayaram, M.
10.1101/2020.12.21.423798 — Posted: 2020-12-21 — Discussion: 2021-11-03  eLife
Cryo-EM Structures of CTP Synthase Filaments Reveal Mechanism of pH-Sensitive Assembly During Budding Yeast Starvation
Hansen, J. M., Horowitz, A., Lynch, E. M., Farrell, D. P., Quispe, J., DiMaio, F., Kollman, J. M.
10.1101/2021.08.25.457724 — Posted: 2021-08-26 — Discussion: 2021-11-01  eLife
Allosteric cooperation in β-lactam binding to a non-classical transpeptidase
Ahmad, N., Kachhap, S., Chauhan, V., Juneja, P., Sharma, K., Bullen, C. K., Borowski, T., Bishai, W. R., Lamichhane, G., Kumar, P.
10.1101/2021.09.06.459080 — Posted: 2021-09-06 — Discussion: 2021-10-28  eLife
Assessing target engagement using proteome-wide solvent shift assays
Van Vranken, J. G., Li, J., Navarrete Perea, J., Gygi, S. P.
10.1101/2021.07.22.453338 — Posted: 2021-07-22 — Discussion: 2021-10-28  eLife

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