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362 Reviews — eLife — Biochemistry

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Structural Basis for an Unprecedented Enzymatic Alkylation in Cylindrocyclophane Biosynthesis
Braffman, N. R., Ruskoski, T. B., Davis, K. M., Glasser, N. R., Johnson, C., Okafor, D., Boal, A. K., Balskus, E. P.
10.1101/2021.12.02.470901 — Posted: 2021-12-02 — Discussion: 2022-02-04  eLife
A Cryptic K48 Ubiquitin Chain Binding Site on UCH37 is Required for its Role in Proteasomal Degradation
Du, J., Babik, S., Li, Y., Deol, K. K., Eyles, S. J., Fejzo, J., Tonelli, M., Strieter, E.
10.1101/2021.11.15.468727 — Posted: 2021-11-15 — Discussion: 2022-02-03  eLife
Creation of photocyclic vertebrate rhodopsin by single amino acid substitution
Yamashita, T., Sakai, K., Imamoto, Y., Shichida, Y.
10.1101/2021.12.06.471433 — Posted: 2021-12-06 — Discussion: 2022-01-26  eLife
Molecular architecture of the human tRNA ligase complex
Kroupova, A., Ackle, F., Boneberg, F. M., Chui, A., Weitzer, S., Faini, M., Leitner, A., Aebersold, R., Martinez, J., Jinek, M.
10.1101/2021.07.11.451954 — Posted: 2021-07-12 — Discussion: 2022-01-26  eLife
Glypican-1 drives unconventional secretion of Fibroblast Growth Factor 2
Sparn, C., Dimou, E., Meyer, A., Saleppico, R., Wegehingel, S., Gerstner, M., Klaus, S., Ewers, H., Nickel, W.
10.1101/2021.11.11.468179 — Posted: 2021-11-12 — Discussion: 2022-01-17  eLife
Autoinhibition and regulation by phosphoinositides of ATP8B1, a human lipid flippase associated with intrahepatic cholestatic disorders
Dieudonne, T., Herrera, S. A., Laursen, M. J., Lejeune, M., Stock, C., Slimani, K., Jaxel, C., Lyons, J. A., Montigny, C., Pomorski, T. G., Nissen, P., Lenoir, G.
10.1101/2021.11.03.467174 — Posted: 2021-11-04 — Discussion: 2022-01-07  eLife
METTL3 promotes homologous recombination repair and modulates chemotherapeutic response by regulating the EGF/Rad51 axis
Li, E., Xia, M., Du, Y., Long, K., Ji, F., Pan, F., He, L., Hu, Z., Guo, Z.
10.1101/2021.11.11.468249 — Posted: 2021-11-12 — Discussion: 2021-12-30  eLife
A proteome-wide screen uncovers diverse roles for sequence context surrounding proline-rich motifs in Ena/VASP molecular recognition
Hwang, T., Parker, S. S., Hill, S. M., Ilunga, M. W., Grant, R. A., Sivaraman, V., Mouneimne, G., Keating, A. E.
10.1101/2021.03.22.436451 — Posted: 2021-03-22 — Discussion: 2021-12-23  eLife
Structure insights of the human peroxisomal ABC transporter ALDP
Jia, Y., Zhang, Y., Lei, J., Yang, G.
10.1101/2021.09.24.461756 — Posted: 2021-09-25 — Discussion: 2021-12-21  eLife
Structure of the human ATM kinase and mechanism of Nbs1 binding
Warren, C., Pavletich, N. P.
10.1101/2021.10.17.464701 — Posted: 2021-10-17 — Discussion: 2021-12-20  eLife

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