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368 Reviews — eLife — Biochemistry

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The orphan ligand, Activin C, signals through activin receptor-like kinase 7
Goebel, E. J., Ongaro, L., Kappes, E. C., Belcheva, E., Castonguay, R., Kumar, R., Bernard, D. J., Thompson, T.
10.1101/2022.03.16.484571 — Posted: 2022-03-16 — Discussion: 2022-05-27  eLife
Structure-Activity Relationships in the Design of Mitochondria-Targeted Peptide Therapeutics
Mitchell, W., Tamucci, J., Ng, E., Liu, S., Szeto, H. H., May, E. R., Alexandrescu, A., Alder, N. N.
10.1101/2021.11.08.467832 — Posted: 2021-11-09 — Discussion: 2022-05-27  eLife
Towards a molecular mechanism underlying mitochondrial protein import through the TOM-TIM23 complex
Ford, H. C., Allen, W. J., Pereira, G. C., Liu, X., Dillingham, M. S., Collinson, I.
10.1101/2021.08.30.458282 — Posted: 2021-08-31 — Discussion: 2022-05-23  eLife
Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases
Mehta, V., Khanppnavar, B., Schuster, D., Vercellino, I., Kosturanova, A., Iype, T., Stefanic, S., Picotti, P., Korkhov, V. M.
10.1101/2021.12.01.470738 — Posted: 2021-12-01 — Discussion: 2022-05-20  eLife
Conserved structural elements specialize ATAD1 as a membrane protein extraction machine
Wang, L., Toutkoushian, H., Kokontis, C. Y., Walter, P., Belyy, V.
10.1101/2021.09.24.461712 — Posted: 2021-09-25 — Discussion: 2022-05-16  eLife
DIP2 is a unique regulator of diacylglycerol lipid homeostasis in eukaryotes
Mondal, S., Kinatukara, P., Singh, S., Shambhavi, S., Patil, G. S., Dubey, N., Singh, S. H., Pal, B., Shekar, P. C., Kamat, S. S., Sankaranarayanan, R.
10.1101/2022.02.07.479356 — Posted: 2022-02-07 — Discussion: 2022-05-13  eLife
A novel 5' DNA binding site in RFC facilitates PCNA loading for gap DNA repair
Zhang, F., Georgescue, R., Yao, N. Y., Li, H., O'Donnell, M. E.
10.1101/2022.02.04.479194 — Posted: 2022-02-05 — Discussion: 2022-05-03  eLife
Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes
Siraliev-Perez, E., Sondek, J., Temple, B. R. S., Zhang, Q., Hajicek, N., Burke, J. E., Stariha, J. T., Hoffmann, R. M., Jenkins, M. L.
10.1101/2022.02.23.481568 — Posted: 2022-02-24 — Discussion: 2022-04-29  eLife
Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission
Wenzel, D. M., Mackay, D. R., Skalicky, J. J., Paine, E. L., Miller, M. S., Ullman, K. S., Sundquist, W. I.
10.1101/2022.02.09.477148 — Posted: 2022-02-10 — Discussion: 2022-04-29  eLife
Hypertrophic cardiomyopathy mutations in the pliant and light chain-binding regions of the lever arm of human β-cardiac myosin have divergent effects on myosin function
Morck, M., Bhowmik, D., Dawood, A., Spudich, J., Ruppel, K. M.
10.1101/2021.10.11.463966 — Posted: 2021-10-12 — Discussion: 2022-04-28  eLife

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