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540 Reviews — All Partners — Biochemistry

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Structure-guided mutagenesis of OSCAs reveals differential activation to mechanical stimuli
Jojoa Cruz, S., Dubin, A. E., Lee, W.-H., Ward, A. B.
10.1101/2023.10.03.560740 — Posted: 2023-10-03 — Discussion: 2024-02-29  eLife
The cryo-EM structure of ASK1 reveals an asymmetric architecture allosterically modulated by TRX1
Honzejkova, K., Kosek, D., Obsilova, V., Obsil, T.
10.1101/2023.12.20.572539 — Posted: 2023-12-20 — Discussion: 2024-02-29  eLife
Structural Mechanisms for VMAT2 inhibition by tetrabenazine
Dalton, M. P., Cheng, M. H., Bahar, I., Coleman, J. A.
10.1101/2023.09.05.556211 — Posted: 2023-09-05 — Discussion: 2024-02-28  eLife
The non-muscle actinopathy-associated mutation E334Q in cytoskeletal gamma-actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins
Greve, J. N., Marquardt, A., Heiringhoff, R., Reindl, T., Thiel, C., Di Dinato, N., Taft, M. H., Manstein, D. J.
10.1101/2023.09.10.557040 — Posted: 2023-09-10 — Discussion: 2024-02-27  eLife
DBF4, not DRF1, is the crucial regulator of CDC7 kinase at replication forks
Göder, A., Maric, C., Rainey, M. D., Cazzaniga, C., Shamavu, D., Cadoret, J.-C., Santocanale, C.
10.1101/2023.12.13.568031 — Posted: 2023-12-13 — Discussion: 2024-02-24  Review Commons
Structural basis of closed groove scrambling by a TMEM16 protein
Feng, Z., Alvarenga, O. E., Accardi, A.
10.1101/2023.08.11.553029 — Posted: 2023-08-12 — Discussion: 2024-02-22  Biophysics Colab
The catalytic mechanism of the RNA methyltransferase METTL3
Corbeski, I., Vargas-Rosales, P. A., Bedi, R. K., Deng, J., Coelho, D., Braud, E., Iannazzo, L., Li, Y., Huang, D., Etheve-Quelquejeu, M., Cui, Q., Caflisch, A.
10.1101/2023.09.06.556513 — Posted: 2023-09-06 — Discussion: 2024-02-21  eLife
Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens
Ober, V., Githure, G. B., Volpato Santos, Y., Becker, S., Moya, G., Basquin, J., Schwede, F., Lorentzen, E., Boshart, M.
10.1101/2023.10.24.563761 — Posted: 2023-10-24 — Discussion: 2024-02-19  eLife
Rapid, DNA-induced subunit exchange by DNA gyrase
Germe, T., Bush, N. G., Baskerville, V., Saman, D., Benesch, J. L., Maxwell, A.
10.1101/2022.09.08.507137 — Posted: 2022-09-08 — Discussion: 2024-02-12  eLife
Semi-synthetic nanobody-ligand conjugates exhibit tunable signaling properties and enhanced transcriptional outputs at neurokinin receptor-1
Braga Emidio, N., Cheloha, R.
10.1101/2023.10.08.561411 — Posted: 2023-10-08 — Discussion: 2024-02-02  Biophysics Colab

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