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348 Reviews — eLife — Biochemistry

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Nuclear bodies protect phase separated proteins from degradation in stressed proteome
Jung, K. H., Sun, J., Hsiung, C.-H., Lian, X., Liu, Y., Zhang, X.
10.1101/2023.04.19.537522 — Posted: 2023-04-21 — Discussion: 2023-06-21  eLife
Genome-wide screen reveals Rab12 GTPase as a critical activator of pathogenic LRRK2 kinase
Dhekne, H. S., Tonelli, F., Yeshaw, W. M., Chiang, C. Y., Limouse, C., Jaimon, E., Purlyte, E., Alessi, D. R., Pfeffer, S. R.
10.1101/2023.02.17.529028 — Posted: 2023-02-18 — Discussion: 2023-06-17  eLife
Conformational dynamics and target-dependent myristoyl switch of calcineurin B homologous protein 3
Becker, F., Fuchs, S., Refisch, L., Drepper, F., Bildl, W., Schulte, U., Liang, S., Heinicke, J. I., Hansen, S. C., Kreutz, C., Warscheid, B., Fakler, B., Mymrikov, E. V., Hunte, C.
10.1101/2022.09.23.509142 — Posted: 2022-09-23 — Discussion: 2023-06-12  eLife
Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain
Harris, N. J., Jenkins, M. L., Nam, S.-E., Rathinaswamy, M. K., Parson, M. A., Ranga-Prasad, H., Dalwadi, U., Moeller, B. E., Sheeky, E., Hansen, S. D., Yip, C. K., Burke, J. E.
10.1101/2023.04.12.536585 — Posted: 2023-04-12 — Discussion: 2023-06-09  eLife
The disordered N-terminus of McdB modulates phase separation via pH-sensitive hydration and folds upon interaction with McdA
Basalla, J. L., Mak, C. A., Limcaoco, M. J., Hoang, Y., Vecchiarelli, A. G.
10.1101/2022.04.28.489914 — Posted: 2022-04-28 — Discussion: 2023-06-09  eLife
A novel Single Alpha-Helix-DNA-binding domain in CAF-1 promotes gene silencing and DNA damage survival through tetrasome-length DNA selectivity and spacer function
Rosas, R., Aguilar, R. R., Arslanovic, N., Tyler, J. K., Churchill, M. E. A.
10.1101/2022.10.11.511754 — Posted: 2022-10-11 — Discussion: 2023-05-23  eLife
Proteostasis is differentially modulated by inhibition of translation initiation or elongation
Clay, K. J., Yang, Y., Petrascheck, M.
10.1101/2022.01.23.477418 — Posted: 2022-01-24 — Discussion: 2023-05-17  eLife
The structural basis of the multi-step allosteric activation of Aurora B kinase
Sekulic, N., Segura-Pena, D., Hovet, O., Gogoi, H., Dawicki-McKenna, J. M., Hansen Woien, S. M., Carrer, M., Black, B. E., Cascella, M.
10.1101/2022.11.23.517677 — Posted: 2022-11-24 — Discussion: 2023-05-15  eLife
An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability
Jain, K., Marunde, M. R., Burg, J. M., Gloor, S. L., Joseph, F. M., Gillespie, Z. B., Rodriguez, K. L., Howard, S. A., Popova, I. K., Hall, N. W., Vaidya, A., Cooke, S. W., Namitz, K. E. W., Taylor, B. C., Weinzapfel, E. N., Cheek, M. A., Meiners, M. J., Krajewski, K., Cosgrove, M. S., Young, N. L., Keogh, M.-C., Strahl, B. D.
10.1101/2022.02.28.482307 — Posted: 2022-02-28 — Discussion: 2023-05-15  eLife
Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution
Duffet, L., Williams, E. T., Gresch, A., Chen, S., Bhat, M. A., Benke, D., Hartrampf, N., Patriarchi, T.
10.1101/2023.02.14.528498 — Posted: 2023-02-16 — Discussion: 2023-05-11  eLife

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