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513 Reviews — All Partners — Biochemistry

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Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γsecretase impairing downstream cell signaling
Zoltowska, K. M., Utpal, D., Lismont, S., Enzlein, T., Maesako, M., Houser, M. C., Gomes Moreira, D., Franco, M. L., Karachentsev, D., Becker, A., Hopf, C., Vilar, M., Berezovska, O., Mobley, W., Chavez-Gutierrez, L.
10.1101/2023.08.02.551596 — Posted: 2023-08-02 — Discussion: 2024-05-29  eLife
A robust method for measuring aminoacylation through tRNA-Seq
Davidsen, K., Sullivan, L. B.
10.1101/2023.07.31.551363 — Posted: 2023-08-01 — Discussion: 2024-05-28  eLife
Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase
Diaz, R. E., Ecker, A. K., Correy, G. J., Asthana, P., Young, I. D., Faust, B., Thompson, M. C., Seiple, I. B., Van Dyken, S. J., Locksley, R. M., Fraser, J. S.
10.1101/2023.06.03.542675 — Posted: 2023-06-03 — Discussion: 2024-05-24  eLife
Cholesterol regulates plasma membrane bending by prominin-family proteins
Bell, T. A., Luce, B. E., Hakim, P., Dardari, H., Ananda, V. Y., Nguyen, T. H., Monshizedeh, A., Chao, L. H.
10.1101/2023.11.08.566258 — Posted: 2023-11-08 — Discussion: 2024-05-24  Review Commons
The folding-limited nucleation of curli hints at an evolved safety mechanism for functional amyloid production
Claridge, J. K., Martens, C., Pradhan, B., Sobott, F., Sleutel, M., Remaut, H.
10.1101/2023.05.26.542396 — Posted: 2023-05-26 — Discussion: 2024-05-23  Biophysics Colab
Structural analysis of the dynamic ribosome-translocon complex
Lewis, A. J. O., Hegde, R. S.
10.1101/2023.12.22.572959 — Posted: 2023-12-22 — Discussion: 2024-05-23  eLife
Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4
Ravala, S. K., Adame-Garcia, S. R., Li, S., Chen, C.-L., Cianfrocco, M. A., Gutkind, J. S., Cash, J. N., Tesmer, J. J. G.
10.1101/2023.09.15.557836 — Posted: 2023-09-16 — Discussion: 2024-05-15  eLife
Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder-Robinson syndrome: mechanism of action and therapeutic potential
Stewart, T. R. M., Foley, J. R., Holbert, C. E., Khomutov, M. A., Rastkari, N., Tao, X., Khomutov, A. R., Zhai, R. G., Casero, R. A.
10.1101/2023.03.30.534977 — Posted: 2023-03-30 — Discussion: 2024-05-15  EMBO Press
ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6 specific nanobody restricts M. tuberculosis growth in macrophages
Bates, T. A., Trank-Greene, M., Nguyenla, X., Anastas, A., Merutka, I. R., Dixon, S. D., Shumate, A., Groncki, A. R., Parson, M. A., Barklis, E., Burke, J. E., Shinde, U., Ploegh, H. L., Tafesse, F. G.
10.1101/2023.08.16.553641 — Posted: 2023-08-17 — Discussion: 2024-05-09  eLife
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms
Bendzunas, G., Byrne, D. P., Shrestha, S., Daly, L. A., Oswald, S. O., Katiyar, S., Venkat, A., Yeung, W., Eyers, C. E., Eyers, P. A., Kannan, N.
10.1101/2023.10.05.561145 — Posted: 2023-10-06 — Discussion: 2024-05-01  eLife

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