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370 Reviews — eLife — Biochemistry

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Affinity-ranking BIN1 interactions and screening natural BIN1 variants that may cause neuromuscular disorders
Zambo, B., Edelweiss, E., Morlet, B., Negroni, L., Ostergaard, S., Laporte, J., Trave, G., Gogl, G.
10.1101/2023.02.14.528471 — Posted: 2023-02-14 — Discussion: 2024-06-20  eLife
Kinases in motion: impact of protein and small molecule interactions on kinase conformations
Kugler, V., Schwaighofer, S., Feichtner, A., Enzler, F., Fleischmann, J., Strich, S., Schwarz, S., Wilson, R., Tschaikner, P., Troppmair, J., Sexl, V., Meier, P., Kaserer, T., Stefan, E.
10.1101/2024.01.11.575270 — Posted: 2024-01-12 — Discussion: 2024-06-17  eLife
Toxin-based screening of C-terminal tags in Escherichia coli reveals the exceptional potency of ssrA-like degrons
Beardslee, P. C., Schmitz, K. R.
10.1101/2024.01.29.576913 — Posted: 2024-01-31 — Discussion: 2024-06-13  eLife
Allosteric activation of the co-receptor BAK1 by the EFR receptor kinase initiates immune signaling
Mühlenbeck, H., Tsutsui, Y., Lemmon, M., Bender, K. W., Zipfel, C.
10.1101/2023.08.23.554490 — Posted: 2023-08-25 — Discussion: 2024-06-12  eLife
Activity modulation in anaerobic ribonucleotide reductases: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site
Bimai, O., Banerjee, I., Grinberg, I. R., Huang, P., Lundin, D., Sjöberg, B.-M., Logan, D. T.
10.1101/2023.06.20.545753 — Posted: 2023-06-20 — Discussion: 2024-06-12  eLife
Fitness landscape of substrate-adaptive mutations in evolved APC transporters
Karapanagioti, F., Atlason, U. A., Slotboom, D. J., Poolman, B., Obermaier, S.
10.1101/2023.10.12.562049 — Posted: 2023-10-12 — Discussion: 2024-06-07  eLife
Deep Mutagenesis of a Transporter for Uptake of a Non-Native Substrate Identifies Conformationally Dynamic Regions
Young, H. J., Chan, M., Selvam, B., Szymanski, S. K., Shukla, D., Procko, E.
10.1101/2021.04.19.440442 — Posted: 2021-04-19 — Discussion: 2024-06-06  eLife
Bacterial exonuclease III expands its enzymatic activities on single-stranded DNA
Wang, H., Ye, C., Lu, Q., Jiang, Z., Jiang, C., Zhou, C., Li, N., Zhang, C., Zhao, G., Yue, M., Li, Y.
10.1101/2024.01.13.575533 — Posted: 2024-01-17 — Discussion: 2024-06-04  eLife
Single-molecule Ligand Response of Guanidine-IV riboswitch
Gao, L., Chen, D., Liu, Y.
10.1101/2023.12.05.570130 — Posted: 2023-12-05 — Discussion: 2024-05-31  eLife
Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γsecretase impairing downstream cell signaling
Zoltowska, K. M., Utpal, D., Lismont, S., Enzlein, T., Maesako, M., Houser, M. C., Gomes Moreira, D., Franco, M. L., Karachentsev, D., Becker, A., Hopf, C., Vilar, M., Berezovska, O., Mobley, W., Chavez-Gutierrez, L.
10.1101/2023.08.02.551596 — Posted: 2023-08-02 — Discussion: 2024-05-29  eLife

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