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562 Reviews — All Partners — Biochemistry

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Reduction of DNA Topoisomerase Top2 reprograms the epigenetic landscape and extends health and life span across species
Zhu, M., Ma, M., Luo, L., Li, F., Zhang, J., Pan, Y., Yang, L., Xiao, Y., Wang, Z., Xian, B., Zheng, Y., Li, H., Yang, J.
10.1101/2024.11.14.623693 — Posted: 2024-11-15 — Discussion: 2025-01-22  eLife
Molecular determinants of Neu5Ac binding to tripartite ATP independent periplasmic (TRAP) transporter
Goyal, P., Dhanabalan, K., Scalise, M., Friemann, R., Indiveri, C., Dobson, R. C., Vinothkumar, K. R., Subramanian, R.
10.1101/2024.03.29.587382 — Posted: 2024-03-30 — Discussion: 2025-01-22  eLife
Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production
Arafi, P., Devkota, S., Maesako, M., Wolfe, M. S.
10.1101/2024.08.30.610520 — Posted: 2024-08-31 — Discussion: 2025-01-17  eLife
Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome
Cozzolino, K., Sanford, L., Hunter, S., Molison, K., Erickson, B., Jones, T., Ajit, D., Galbraith, M. D., Espinosa, J. M., Bentley, D. L., Allen, M. A., Dowell, R. D. A., Taatjes, D. J.
10.1101/2023.07.05.547813 — Posted: 2023-07-05 — Discussion: 2025-01-17  eLife
Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant
Tomlinson, P. R., Knox, R., Perisic, O., Su, H., Brierley, G. V., Williams, R. L., Semple, R. K.
10.1101/2023.11.02.565250 — Posted: 2023-11-02 — Discussion: 2025-01-03  eLife
The conserved biochemical activity and function of an early metazoan phosphatidylinositol 5 phosphate 4-kinase regulates growth and development.
Krishnan, H., Muzaffar, S., Sharma, S., Ramya, V., Ghosh, A., Sowdhamini, R., PADINJAT, R.
10.1101/2024.08.01.606031 — Posted: 2024-08-01 — Discussion: 2025-01-03  Review Commons
4G cloning: rapid gene assembly for expression of multisubunit protein complexes in diverse hosts
Taschner, M., Dickinson, J. B., Roisne-Hamelin, F., Gruber, S.
10.1101/2024.06.17.599261 — Posted: 2024-06-17 — Discussion: 2024-12-14  EMBO Press
The co-receptor Tspan12 directly captures Norrin to promote ligand-specific β-catenin signaling
Bruguera, E. S., Mahoney, J. P., Weis, W. I.
10.1101/2024.02.03.578714 — Posted: 2024-02-03 — Discussion: 2024-12-13  eLife
Protonation/deprotonation-driven switch for the redox stability of low-potential ferredoxin
Wada, K., Kobayashi, K., Era, I., Isobe, Y., Kamimura, T., Marukawa, M., Nagae, T., Honjo, K., Kaseda, N., Motoyama, Y., Inoue, K., Sugishima, M., Kusaka, K., Yano, N., Fukuyama, K., Mishima, M., Kitagawa, Y., Unno, M.
10.1101/2024.09.12.612615 — Posted: 2024-09-14 — Discussion: 2024-12-09  eLife
Interactions with multiple inner kinetochore proteins determine mitotic localization of FACT
Schweighofer, J., Mulay, B., Hoffmann, I., Vogt, D., Pesenti, M. E., Musacchio, A.
10.1101/2024.06.14.599021 — Posted: 2024-06-14 — Discussion: 2024-12-05  Review Commons

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