Channel:  Francis Crick Institute

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

925 Articles

The atypical Rho GTPase Rnd2 is critical for dentate granule neuron development and anxiety-like behavior during adult but not neonatal neurogenesis
Kerloch, T., Farrugia, F., Maitre, M., Terral, G., Koehl, M., Heng, J. I.-T., Blanchard, M., Doat, H., Leste-Lasserre, T., Goron, A., Gonzales, D., Guillemot, F., Abrous, N., Pacary, E.
10.1101/2020.09.10.290866 — Posted: 2020-09-10
Highly enriched hiPSC-derived midbrain dopaminergic neurons robustly models Parkinson's disease.
Virdi, G. S., Choi, M. L., Yao, Z., Evans, J. R., Athauda, D., Melandri, D., Sylantyev, S., Abramov, A. Y., Patani, R., Gandhi, S.
10.1101/2020.09.08.287797 — Posted: 2020-09-08
Generating single-sex litters: development of CRISPR-Cas9 genetic tools to produce all-male offspring
Douglas, C., Maciulyte, V., Zohren, J., Snell, D. M., Ojarikre, O. A., Ellis, P. J., Turner, J. M. A.
10.1101/2020.09.07.285536 — Posted: 2020-09-07
Plasmodium falciparum guanylyl cyclase-alpha and the activity of its appended P4-ATPase domain are essential for cGMP synthesis and blood stage egress
Nofal, S. D., Patel, A., Blackman, M. J., Flueck, C., Baker, D. A.
10.1101/2020.09.07.285734 — Posted: 2020-09-07
Assessing the acoustic behaviour of Anopheles gambiae s.l. dsxF mutants: Implications for Vector Control
Su, M. P., Georgiades, M., Bagi, J., Kyrou, K., Crisanti, A., Albert, J.
10.1101/2020.09.06.284679 — Posted: 2020-09-06
Training a neural network to learn other dimensionality reduction removes data size restrictions in bioinformatics and provides a new route to exploring data representations
Dexter, A., Thomas, S. A., Steven, R. T., Robinson, K. N., Taylor, A. J., Elia, E., Nikula, C., Campbell, A. D., Panina, Y., Najumudeen, A. K., Murta, T., Yan, B., Grabowski, P., Hamm, G., Swales, J., Gilmore, I., Yuneva, M., Goodwin, R. J. A., Barry, S., Sansom, O. J., Takats, Z., Bunch, J.
10.1101/2020.09.03.269555 — Posted: 2020-09-03
A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses
Tan, T. K., Rijal, P., Rahikainen, R., Keeble, A., Schimanski, L., Hussain, S., Harvey, R., Hayes, J., Edwards, J., McLean, R., Martini, V., Pedrera, M., Thakur, N., Conceicao, C., Dietrich, I., Shelton, H., Ludi, A. B., Wilsden, G., Browning, C., Zagrajek, A., Bialy, D., Bhat, S., Stevenson-Leggett, P., Hollinghurst, P., Tully, M., Moffat, K., Chiu, C., Waters, R., Gray, A., Azhar, M., Mioulet, V., Newman, J., Asfor, A. S., Burman, A., Crossley, S., Hammond, J., Tchilian, E., Charleston, B., Bailey, D., Tuthill, T. J., Graham, S., Malinauskas, T., Huo, J., Tree, J., Buttigieg, K., Owens, R.
10.1101/2020.08.31.275701 — Posted: 2020-08-31
Modulation of the cAMP levels with a conserved actinobacteria phosphodiesterase enzyme reduces antimicrobial tolerance in mycobacteria
Thomson, M., Nunta, K., Cheyne, A., Liu, Y., Garza-Garcia, A., Larrouy-Maumus, G.
10.1101/2020.08.26.267864 — Posted: 2020-08-26
An Integrative Analysis of the Age-Associated Genomic, Transcriptomic and Epigenetic Landscape across Cancers
Chatsirisupachai, K., Lesluyes, T., Paraoan, L., Van Loo, P., de Magalhaes, J. P.
10.1101/2020.08.25.266403 — Posted: 2020-08-25
MRE11 is crucial for malaria transmission and its absence affects expression of interconnected networks of key genes essential for life
Guttery, D., Ramaprasad, A., Ferguson, D., Zeeshan, M., Pandey, R., Brady, D., Holder, A. A., Pain, A., Tewari, R.
10.1101/2020.08.24.258657 — Posted: 2020-08-24

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