Channel:  SCORCH

19 Articles

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Spatial isoform sequencing at sub-micrometer single-cell resolution reveals novel patterns of spatial isoform variability in brain cell types
Michielsen, L., Prjibelski, A. D., Foord, C., Hu, W., Jarroux, J., Hsu, J., Tomescu, A. I., Hajirasouliha, I., Tilgner, H. U.
10.1101/2025.06.25.661563 — Posted: 2025-09-30
Quantitative Economon Model of Transactions for Drugs and Other Commodities
Haynes, J. M., Correa da Rosa, J. M., Butelman, E., Hursh, S. R., Negus, S. S.
10.1101/2025.07.08.663082 — Posted: 2025-07-11
A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types.
Foord, C., Prjibelski, A. D., Hu, W., Michielsen, L., Vandelli, A., Narykov, O., Evans, B., Hsu, J., Belchikov, N., Jarroux, J., He, Y., Ross, M. E., Hajirasouliha, I., Tartaglia, G. G., Korkin, D., Tomescu, A. I., Tilgner, H. U.
10.1101/2025.06.10.658877 — Posted: 2025-06-10
Cell type-specific contributions to impaired blood-brain barrier and cerebral metabolism in presymptomatic 5XFAD mice
Yao, M., Sun, N., Linville, R., Wei, Z., Kakazu, A., Ouyang, Y., Li, R., Du, L., Wang, H., Zhou, Y., Jiang, Y., Zhang, Z., Li, A., Lu, H., Xu, J., Kellis, M., Heiman, M., Duan, W.
10.1101/2025.04.23.650260 — Posted: 2025-04-29
Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microglia
Wilson, A. M., Jacobs, M. M., Lambert, T. Y., Valada, A., Meloni, G., Gilmore, E., Murray, J., Morgello, S., Akbarian, S.
10.1101/2025.02.05.636667 — Posted: 2025-02-08
Multi-omic Characterization of HIV Effects at Single Cell Level across Human Brain Regions
Yang, J., Agrawal, K., Stanley, J. S., Li, R., Jacobs, N., Wang, H., Lu, C., Qu, R., Clarke, D., Chen, Y., Jiang, Y., Bai, D., Zheng, S., Fox, H., Ho, Y.-C., Huttner, A., Gerstein, M., Kluger, Y., Zhang, L., Spudich, S.
10.1101/2025.02.05.636707 — Posted: 2025-02-08
Principled PCA separates signal from noise in omics count data
Stanley, J. S., Yang, J., Li, R., Lindenbaum, O., Kobak, D., Landa, B., Kluger, Y.
10.1101/2025.02.03.636129 — Posted: 2025-02-07
BACH2-driven tissue resident memory programs promote HIV-1 persistence
Wei, Y., Ma, H. K., Wang, M. E., Papasavvas, E., Konnikova, L., Tebas, P., Morgenstern, R., Montaner, L. J., Ho, Y.-C.
10.1101/2024.12.16.628794 — Posted: 2024-12-20
Scaling deep identifiable models enables zero-shot characterization of single-cell biological states
Dong, M., Agrawal, K., Fan, R., Sefik, E., Flavell, R. A., Kluger, Y.
10.1101/2023.11.11.566161 — Posted: 2024-12-18
A Transcriptional Signature of Induced Neurons Differentiates Virologically Suppressed People Living With HIV from People Without HIV
Ostermann, P. N., Wu, Y., Bowler, S. A., Siddiqui, M. A., Herrera, A., Sidharta, M., Ramnarine, K., Martinez-Meza, S., St. Bernard, L. A., Nixon, D. F., Jones, R. B., Yamashita, M., Ndhlovu, L. C., Zhou, T., Evering, T. H.
10.1101/2024.10.22.619617 — Posted: 2024-10-22

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