Channel: The Whitehead Institute

34 Articles

The phenotypic landscape of essential human genes

Funk, L., Su, K.-C., Feldman, D., Singh, A., Moodie, B., Blainey, P., Cheeseman, I. M.

10.1101/2021.11.28.470116 — Posted: 2021-11-28

Krüppel-like factor 4 is required for development and regeneration of germline and yolk cells from somatic stem cells in planarians

Issigonis, M., Redkar, A., Rozario, T., Khan, U., Mejia-Sanchez, R., Lapan, S., Reddien, P., Newmark, P. A.

10.1101/2021.11.08.467675 — Posted: 2021-11-08

A phosphoregulated RhoGEF feedback loop tunes cortical flow driven amoeboid migration in vivo

Lin, B., Luo, J., Lehmann, R.

10.1101/2021.10.29.466358 — Posted: 2021-10-29

Alternative Cdc20 translational isoforms bypass the spindle assembly checkpoint to control mitotic arrest duration

Tsang, M. J., Cheeseman, I. M.

10.1101/2021.10.24.465552 — Posted: 2021-10-24

Lineage Recording Reveals the Phylodynamics, Plasticity and Paths of Tumor Evolution

Yang, D., Jones, M. G., Naranjo, S., Rideout, W. M., Min, K. H. J., Ho, R., Wu, W., Replogle, J. M., Page, J. L., Quinn, J. J., Horns, F., Qiu, X., Chen, M. Z., Freed-Pastor, W. A., McGinnis, C. S., Patterson, D. M., Gartner, Z. J., Chow, E. D., Bivona, T. G., Chan, M. M., Yosef, N., Jacks, T., Weissman, J. S.

10.1101/2021.10.12.464111 — Posted: 2021-10-13

Single-molecule analysis of specificity and multivalency in binding of short linear substrate motifs to the APC/C

Hartooni, N., Sung, J., Jain, A., Morgan, D. O.

10.1101/2021.09.25.461797 — Posted: 2021-09-26

High-throughput functionalization of the Toxoplasma kinome uncovers a novel regulator of invasion and egress

Smith, T. A., Lopez-Perez, G. S., Shortt, E., Lourido, S.

10.1101/2021.09.23.461611 — Posted: 2021-09-24

Flanking sequences regulate the toxicity, non-ATG translation, and aggregation of RNA with tandem CAG Repeats

Das, M. R., Chang, Y., Saunders, R., Zhang, N., Tomberlin, C., Vale, R. D., Jain, A.

10.1101/2021.08.30.458106 — Posted: 2021-08-31

RNA Pol IV has antagonistic parent-of-origin effects on Arabidopsis endosperm

Satyaki, P. R. V., Gehring, M.