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The phylogenetic context for the origin of a unique purple-green photosymbiosis
Munoz-Gomez, S. A., Sorensen, M. E. S., Shazib, S. U. A., Shin, M. K., Bauer, T., Kreutz, M., Hess, S.
10.64898/2025.12.20.694765 — Posted: 2025-12-22 — Discussion: 2026-01-01  Arcadia Science
Distributed neural computation and the evolution of the first brains
Chandra, V., Nejad, M. R., Kann, A. P., Salem, A., Hill, K. A. P., Mahadevan, L., Srivastava, M.
10.1101/2025.10.03.680388 — Posted: 2025-10-04 — Discussion: 2025-12-31  PREreview
Enzymatic bromination of native peptides for late-stage structural diversification via Suzuki-Miyaura coupling
Bridge, H. N., Radziej, C. L., Weeks, A. M.
10.64898/2025.12.17.694899 — Posted: 2025-12-19 — Discussion: 2025-12-31  preLights
Taxane-Induced Conformational Changes in the Microtubule Lattice Activate GEF-H1-Dependent RhoA Signaling
Meiring, J. C. M., Mahapatra, V., Gravett, M. S. G., Morren, D., Saunders, H. A. J., Choi, S. R., Pelster Jose, A., Karhanova, A., Metallidou, I., Moore, A., Spoelstra, M. F. M., Liu, R., Giono, M., Iyer, S. S., Diaz, F., Lansky, Z., Stecker, K. E., Steinmetz, M., Howes, S., Kapitein, L., Akhmanova, A.
10.64898/2025.12.20.695343 — Posted: 2025-12-23 — Discussion: 2025-12-31  preLights
Ancient Protein Resurrection of an ancestral Arf GTPase that regulates membrane trafficking uncovers dual cellular localization and unanticipated properties of modern Arf1 proteins.
Alves, M., Sivia, M., Zahonova, K., Jackson, C. L., Dacks, J. B.
10.1101/2025.10.27.684887 — Posted: 2025-10-28 — Discussion: 2025-12-30  Arcadia Science
PIP5K-Ras bistability initiates plasma membrane symmetry breaking to regulate cell polarity and migration
Deng, Y., Banerjee, T., Pal, D. S., Banerjee, P., Zhan, H. D., Borleis, J., Iglesias, P. A., Devreotes, P.
10.1101/2024.09.15.613115 — Posted: 2024-09-15 — Discussion: 2025-12-29  preLights
10,239 whole genomes with multiomic and clinical health information as the Korean population multiomic reference dataset
An, K., Jeon, S., Kwon, Y., Yoon, C., Choi, Y., Jeon, Y., Choi, H.-J., Bhak, J., Shin, D.-H., Lee, H., Kim, Y. J., Shin, E.-S., Ryu, H., Blazyte, A., Park, S., Cho, J., Bolser, D., Jeon, J., Joe, S., Yang, J. O., Kim, J.-H., Kim, B.-C., Kim, J., Park, N.-H., Lee, S., Jin, H.-j., Baek, Y., Jung, D., Cho, Y., Ahn, Y. M., Jung, H.-T., Ham, B., Choi, Y. Y., Choi, S. A., Kim, S.-K., Phi, J. H., Gee, H. Y., Kim, B., Myung, W., Cheon, C. K., Kim, D. U., Jin, G.-N., Lee, H., Chae, K. S., Kim, C. G., Lee, B., Lee, J., Lee, S., Church, G. M., Jeong, H., Bhak, J.
10.1101/2025.11.17.688763 — Posted: 2025-11-17 — Discussion: 2025-12-28  Arcadia Science
Predictive design of tissue-specific mammalian enhancers that function in vivo in the mouse embryo
CHEN, S., Loubiere, V., Hollingsworth, E. W., Jacinto, S. H., Dizehchi, A., Schreiber, J., Kvon, E. Z., Stark, A.
10.64898/2025.12.22.695948 — Posted: 2025-12-24 — Discussion: 2025-12-28  Arcadia Science
RemoteFoldSet: Benchmarking Structural Awareness of Protein Language Models
Ma, Z., Bethel, N. P.
10.1101/2025.09.23.678152 — Posted: 2025-09-23 — Discussion: 2025-12-26  Arcadia Science
ProFam: Open-Source Protein Family Language Modelling for Fitness Prediction and Design
Wells, J., Hawkins Hooker, A., Livne, M., Lin, W., Miller, D. M., Dallago, C., Bordin, N., Paige, B., Rost, B., Orengo, C., Heinzinger, M.
10.64898/2025.12.19.695431 — Posted: 2025-12-21 — Discussion: 2025-12-26  Arcadia Science

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