bioRxiv is receiving many new papers on coronavirus SARS-CoV-2.   A reminder: these are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information.

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744 Discussion Links — Arcadia Science — All Subjects

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Co-option of lysosomal machinery shapes the symbiosis supporting coral reefs
Maruyama, S., Henderson, C. F., Swinhoe, N., Kowalewski, G. P., Meier, E. K., Engelke, T. R., Cleves, P. A.
10.1101/2025.10.09.679812 — Posted: 2025-10-09 — Discussion: 2025-10-13  Arcadia Science
Coalescence and Translation: A Language Model for Population Genetics
Korfmann, K., Pope, N., Meleghy, M., Tellier, A., Kern, A. D.
10.1101/2025.06.24.661337 — Posted: 2025-06-27 — Discussion: 2025-10-10  Arcadia Science
From Mechanistic Interpretability to Mechanistic Biology: Training, Evaluating, and Interpreting Sparse Autoencoders on Protein Language Models
Adams, E., Bai, L., Lee, M., Yu, Y., AlQuraishi, M.
10.1101/2025.02.06.636901 — Posted: 2025-02-08 — Discussion: 2025-10-06  Arcadia Science
JIP4 deficiency causes a novel lysosome storage disease arising from impaired cystine efflux
Nassar, L. M., Shi, x., Roczniak-Ferguson, A., Shen, H., Ferguson, S. M.
10.1101/2025.06.06.657909 — Posted: 2025-06-09 — Discussion: 2025-10-03  Arcadia Science
Stress response of membrane-based cell organelles in budding yeast
Sheng, P., Bai, z. L., Cao, H., Li, D.
10.1101/2024.09.08.611912 — Posted: 2024-09-08 — Discussion: 2025-10-03  Arcadia Science
The Implications of Alternative Splicing Regulation for Maximum Lifespan
Zheng, S., Chen, L., Jiang, W.
10.1101/2025.09.23.678147 — Posted: 2025-09-24 — Discussion: 2025-10-03  Arcadia Science
Targeting a novel chloroquine derivative to lysosomes induces massive and irreversible damage to lysosomes and suppresses autophagosomes and lysosomes assembly in cancer
Chauhan, N., Guha Majumdar, A., Bhutia, S. K., Dey, P., Subramanian, M., Patro, B. S.
10.1101/2025.09.07.674530 — Posted: 2025-09-12 — Discussion: 2025-10-03  Arcadia Science
Quantifying a trait-mediated indirect effect of an environmental stressor on population dynamics
Shibasaki, S., Yamamichi, M.
10.1101/2025.09.04.674171 — Posted: 2025-09-08 — Discussion: 2025-10-03  Arcadia Science
Stool Dynamics and the Developing Gut Microbiome During Infancy
Al-Andoli, M., Schoch, S., Markovic, A., Muhlematter, C., Beaugrand, M., Jenni, O., Liamlahi, R., Walser, J.-C., Nielsen, D. S., Kurth, S.
10.1101/2025.06.30.662361 — Posted: 2025-07-04 — Discussion: 2025-10-03  Arcadia Science
IRF2 degradation tunes the innate immune response
Cadena, C., Reja, R., Bolech, E., Webster, J. D., Kameswaran, V., de Simone, M., Jiang, J., Hotzel, K., Alegre, K., Tan, Z., Newland, R., Kelly, R., Darmanis, S., Daniel, B., Deshpande, I., Newton, K., Kayagaki, N., Dixit, V. M.
10.1101/2025.09.23.678148 — Posted: 2025-09-24 — Discussion: 2025-10-02  Arcadia Science

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