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438 Reviews — All Partners — Cancer Biology

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Inhibition of p38-MK2 pathway enhances the efficacy of microtubule inhibitors in breast cancer cells
Chen, Y.-C., Takada, M., Nagornyuk, A., Muhan, W., Yamada, H., Nagashima, T., Ohtsuka, M., DeLuca, J. G., Markus, S. M., Takaku, M., Suzuki, A.
10.1101/2024.11.04.621816 — Posted: 2024-11-07 — Discussion: 2025-05-13  eLife
Integrated Analysis of Single-Cell and Bulk RNA-Seq Data reveals that Ferroptosis-Related Genes Mediated the Tumor Microenvironment predicts Prognosis, and guides Drug Selection in Triple-Negative Breast Cancer
Gong, X., Gu, L., Yang, D., He, Y., Li, Q., Qin, H., Wang, Y.
10.1101/2024.07.04.602021 — Posted: 2024-07-06 — Discussion: 2025-05-09  eLife
Repression of the Wnt pathway effector TCF7L2 reverses lethal cachexia in mice with intestinal cancers
Leong, M. L., Ruedl, C., Karjalainen, K.
10.1101/2024.11.22.624913 — Posted: 2024-11-25 — Discussion: 2025-05-07  eLife
Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
Li, S., Song, K., Sun, H., Tao, Y., Huang, A., Bhatia, V., Hanratty, B., Patel, R. A., Long, H. W., Morrissey, C., Haffner, M. C., Nelson, P. S., Graeber, T. G., Lee, J. K.
10.1101/2025.02.12.637904 — Posted: 2025-02-17 — Discussion: 2025-04-30  eLife
Tumor Cell Spatial Organization Directs EGFR/RAS/RAF Pathway Primary Therapy Resistance through YAP Signaling
Nakagawa, R., Beardsley, A., Durney, S., Hayward, M.-K., Subramanyam, V., Meyer, N. P., Wismer, H., Goodarzi, H., Weaver, V. M., Van de Mark, D., Goga, A.
10.1101/2024.09.26.615226 — Posted: 2024-09-28 — Discussion: 2025-04-25  eLife
Targeting de novo cholesterol synthesis in rhabdomyosarcoma induces cell cycle arrest and triggers apoptosis through ER stress-mediated pathways
Gizaw, N. Y., Kolari, K., alitalo, K., Kivela, R.
10.1101/2024.12.18.628900 — Posted: 2024-12-20 — Discussion: 2025-04-24  Review Commons
Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis
Jonker, P. B., Sadullozoda, M., Cognet, G., Saab, J. J. A., Sokol, K. H., Wu, V. X., Kumari, D., Sheehan, C., Ozgurses, M. E., Agovino, D., Croley, G., Patel, S. A., Bock-Hughes, A., Macleod, K. F., Shah, H., Coloff, J. L., Lien, E. C., Muir, A.
10.1101/2025.03.10.642426 — Posted: 2025-03-13 — Discussion: 2025-04-23  eLife
Targeting SLC7A11-mediated cysteine metabolism for the treatment of trastuzumab resistant HER2 positive breast cancer
Hua, Y., Duan, N., Sun, C., Yang, F., Tian, M., Sun, Y., Zhao, S., Gong, J., Liu, Q., Huang, X., Liang, Y., Fu, Z., Li, W., Yin, Y.
10.1101/2024.11.12.623302 — Posted: 2024-11-15 — Discussion: 2025-04-22  eLife
DuoHexaBody-CD37 induces direct cytotoxic signaling in diffuse large B-cell lymphoma
Pal Singh, S., van den Beukel, M. D., van Deventer, S., Overdijk, M. B., Roukens, G., Santegoets, K. C. M., Breij, E. C. W., ter Beest, M., van Spriel, A. B.
10.1101/2025.02.24.639899 — Posted: 2025-02-28 — Discussion: 2025-04-22  eLife
A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial-mesenchymal transition and stemness in breast cancer
Usman, S., Yeudall, W. A., Teh, M.-T., Ghaloum, F., Tummala, H., Waseem, A.
10.1101/2024.11.13.623301 — Posted: 2024-11-15 — Discussion: 2025-04-22  eLife

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