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268 Reviews — eLife — Cancer Biology

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Therapeutic benefits of maintaining CDK4/6 inhibitors and incorporating CDK2 inhibitors beyond progression in breast cancer
Armand, J., Kim, S., Kim, K., Son, E., Kim, M., Yang, H. W.
10.1101/2024.11.11.623139 — Posted: 2024-11-15 — Discussion: 2025-01-24  eLife
Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning
Estevam, G. O., Linossi, E. M., Rao, J., Macdonald, C. B., Ravikumar, A., Chrispens, K. M., Capra, J. A., Coyote-Maestas, W., Pimentel, H., Collisson, E. A., Jura, N., Fraser, J. S.
10.1101/2024.07.16.603579 — Posted: 2024-07-18 — Discussion: 2025-01-23  eLife
Non-destructive in situ monitoring of structural changes of 3D tumor spheroids during the formation, migration, and fusion process
Ning, K., Xie, Y., Sun, W., Feng, L., Fang, C., Pan, R., Li, Y., Yu, L.
10.1101/2024.07.25.605064 — Posted: 2024-07-25 — Discussion: 2025-01-23  eLife
Blocking SHP2 benefits FGFR2 inhibitor and overcomes its resistance in FGFR2-amplified gastric cancer
Zhang, Y., Wang, H., Wei, Y., Pan, Y., Song, X., Shi, T., Shao, J., Yu, L., Liu, B., Wang, Y., Wei, J.
10.1101/2024.11.04.621870 — Posted: 2024-11-06 — Discussion: 2025-01-16  eLife
Replication stress inducing ELF3 upregulation promotes BRCA1-deficient breast tumorigenesis in luminal progenitors
Zhou, J., Zhou, X. A., Hu, L., Ma, Y., Zhan, J., Xu, Z., Zhou, M., Shen, Q., Xie, Y., Wang, J.
10.1101/2023.07.20.549893 — Posted: 2023-07-20 — Discussion: 2025-01-02  eLife
FORMATION OF MALIGNANT, METASTATIC SMALL CELL LUNG CANCERS THROUGH OVERPRODUCTION OF cMYC PROTEIN IN TP53 AND RB1 DEPLETED PULMONARY NEUROENDOCRINE CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS
Chen, H., Gardner, E. E., Shah, Y., Zhang, K., Thakur, A., Zhang, C., Elemento, O., Varmus, H.
10.1101/2023.10.06.561244 — Posted: 2023-10-10 — Discussion: 2024-12-31  eLife
Single-cell profiling reveals the intratumor heterogeneity and immunosuppressive microenvironment in cervical adenocarcinoma
Peng, Y., Li, Y., Ao, J., Shen, J., He, X., Tang, D., Chu, C., Liu, C., Weng, L.
10.1101/2024.03.20.586024 — Posted: 2024-03-21 — Discussion: 2024-12-24  eLife
Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
Pham, T. H., Pahuja, K. B., Hagenbeek, T. J., Zbieg, J., Noland, C. L., Pham, V. C., Yao, X., Rose, C. M., Browder, K. C., Lee, H.-J., Yu, M., Liang-Chu, M., Martin, S. E., Verschueren, E., Li, J., Kubala, M. H., Fong, R., Lorenzo, M., Beroza, P., Hsu, P., Paul, S., Villemure, E., Lee, W., Cheung, T., Clausen, S., Lacap, J., Liang, Y., Cheng, J., Schmidt, S., Modrusan, Z., Cohen, M. S., Crawford, J., Jasper, H., Ashworth, A., Lill, J. R., Malek, S., Rudolph, J., Wertz, I. E., Chang, M., Ye, X., Dey, A.
10.1101/2023.10.03.560675 — Posted: 2023-10-04 — Discussion: 2024-12-20  eLife
Establishing the foundations for a data-centric AI approach for virtual drug screening through a systematic assessment of the properties of chemical data
Chong, A., Phua, S.-X., Xiao, Y., Ng, W. Y., Li, H. Y., Goh, W. W. B.
10.1101/2024.03.28.587184 — Posted: 2024-03-31 — Discussion: 2024-12-16  eLife
The Role of ATP Synthase Subunit e (ATP5I) in Mediating the Metabolic and Antiproliferative Effects of Biguanides
Lefrancois, G., Lavallee, E., Rowell, M.-C., Bourdeau, V., Mohebali, F., Berthomeu, T., Tyers, M., Gravel, S.-P., Schmitzer, A. R., Ferbeyre, G.
10.1101/2024.09.20.614047 — Posted: 2024-09-24 — Discussion: 2024-12-11  eLife

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