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81 Reviews — EMBO Press — Cancer Biology

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The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism
Xu, R., Jones, W., Wilcz-Villega, E., Costa, S., Rajeeve, V., Bentham, R. B., Bryson, K., Nagano, A., Yaman, B., Olendo Barasa, S., Wang, Y., Chelala, C., Cutillas, P., Szabadkai, G., Frezza, C., Bianchi, K.
10.1101/855361 — Posted: 2019-11-26 — Discussion: 2020-10-06  EMBO Press
Reprogrammed mRNA translation drives metabolic response to therapeutic targeting of ribosome biogenesis
Kusnadi, E. P., Trigos, A. S., Cullinane, C., Goode, D. L., Larsson, O. S., Devlin, J. R., Chan, K. T., DeSouza, D. P., McConville, M. J., McArthur, G. A., Thomas, G., Sanij, E., Poortinga, G., Hannan, R. D., Hannan, K. M., Kang, J., Pearson, R. B.
10.1101/847723 — Posted: 2019-11-20 — Discussion: 2020-10-06  EMBO Press
DDX5 targets tissue-specific RNAs to promote intestine tumorigenesis
Abbasi, N., Long, T., Li, Y., Ma, E., Yee, B. A., Patel, P. R., Sayed, I. M., Varki, N., Das, S., Ghosh, P., Yeo, G. W., Huang, W. J. M.
10.1101/2020.03.25.006668 — Posted: 2020-03-26 — Discussion: 2020-10-06  EMBO Press
Hippo Pathway Deregulation Drives Tissue Stiffness and Cancer Stem-like Cells in Lung Adenocarcinoma
Pankova, D., Jiang, Y., Vendrell, I., Buzzelli, J., Ryan, A. J., Brown, C., O'Neill, E.
10.1101/390849 — Posted: 2018-08-13 — Discussion: 2020-07-15  EMBO Press
Stromal ISLR promotes intestinal regeneration and cancer by suppressing epithelial Hippo signaling
Xu, J., Tang, Y., Sheng, X., Tian, Y., Deng, M., Du, S., Lv, C., Song, Y., Lou, P., Luo, Y., Li, Y., Zhang, B., Chen, Y., Liu, Z., Cong, Y., Plikus, M. V., Meng, Q., Zhou, Z., Yu, Z.
10.1101/740472 — Posted: 2019-08-20 — Discussion: 2020-07-15  EMBO Press
Small molecule inhibitors and a kinase-dead expressing mouse model demonstrate that the kinase activity of Chk1 is essential for mouse embryos and cancer cells
Muralidharan, S. V., Nilsson, L. M., Lindberg, M. F., Nilsson, J. A.
10.1101/2020.01.21.913467 — Posted: 2020-01-21 — Discussion: 2020-07-15  EMBO Press
EZH2 co-opts gain-of-function p53 mutants to promote cancer growth and metastasis
Zhao, Y., Ding, L., Wang, D., Ye, Z., Pan, Y., Ma, L., Coleman, R., Coleman, I., Karnes, R. J., Zhang, J., Nelson, P. S., Wang, L., Zhu, R., Huang, H.
10.1101/298737 — Posted: 2018-04-10 — Discussion: 2020-07-15  EMBO Press
An early Myc-dependent transcriptional program underlies enhanced macromolecular biosynthesis and cell growth during B-cell activation
Amati, B., Sabo, A., Tesi, A., De Pretis, S., Furlan, M., Filipuzzi, M., Morelli, M. J., Andronache, A., Doni, M., Verrecchia, A., Pelizzola, M.
10.1101/561464 — Posted: 2019-02-27 — Discussion: 2020-07-15  EMBO Press
STAT3-dependent systems-level analysis reveals PDK4 as an independent predictor of biochemical recurrence in prostate cancer
Oberhuber, M., Pecoraro, M., Rusz, M., Oberhuber, G., Wieselberg, M., Haslinger, P., Gurnhofer, E., Pencik, J., Wiebringhaus, R., Schlederer, M., Weiss, T., Schmeidl, M., Haitel, A., Brehme, M. J., Wadsak, W., Griss, J., Mohr, T., Hofer, A., Jäger, A., Egger, G., Pollheimer, J., Koellensperger, G., Mann, M., Hantusch, B., Kenner, L.
10.1101/770701 — Posted: 2019-09-19 — Discussion: 2020-07-15  EMBO Press
Preservation of stemness in high-grade serous ovarian cancer organoids requires low Wnt environment
Hoffmann, K., Berger, H., Kulbe, H., Thillainadarasan, S., Mollenkopf, H.-J., Zemojtel, T., Taube, E., Darb-Esfahani, S., Mangler, M., Sehouli, J., Chekerov, R., Braicu, E., Meyer, T. F., Kessler, M.
10.1101/741397 — Posted: 2019-08-21 — Discussion: 2020-06-04  EMBO Press

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