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78 Reviews — EMBO Press — Cancer Biology

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Small molecule inhibitors and a kinase-dead expressing mouse model demonstrate that the kinase activity of Chk1 is essential for mouse embryos and cancer cells
Muralidharan, S. V., Nilsson, L. M., Lindberg, M. F., Nilsson, J. A.
10.1101/2020.01.21.913467 — Posted: 2020-01-21 — Discussion: 2020-07-15  EMBO Press
STAT3-dependent systems-level analysis reveals PDK4 as an independent predictor of biochemical recurrence in prostate cancer
Oberhuber, M., Pecoraro, M., Rusz, M., Oberhuber, G., Wieselberg, M., Haslinger, P., Gurnhofer, E., Pencik, J., Wiebringhaus, R., Schlederer, M., Weiss, T., Schmeidl, M., Haitel, A., Brehme, M. J., Wadsak, W., Griss, J., Mohr, T., Hofer, A., Jäger, A., Egger, G., Pollheimer, J., Koellensperger, G., Mann, M., Hantusch, B., Kenner, L.
10.1101/770701 — Posted: 2019-09-19 — Discussion: 2020-07-15  EMBO Press
Hippo Pathway Deregulation Drives Tissue Stiffness and Cancer Stem-like Cells in Lung Adenocarcinoma
Pankova, D., Jiang, Y., Vendrell, I., Buzzelli, J., Ryan, A. J., Brown, C., O'Neill, E.
10.1101/390849 — Posted: 2018-08-13 — Discussion: 2020-07-15  EMBO Press
Stromal ISLR promotes intestinal regeneration and cancer by suppressing epithelial Hippo signaling
Xu, J., Tang, Y., Sheng, X., Tian, Y., Deng, M., Du, S., Lv, C., Song, Y., Lou, P., Luo, Y., Li, Y., Zhang, B., Chen, Y., Liu, Z., Cong, Y., Plikus, M. V., Meng, Q., Zhou, Z., Yu, Z.
10.1101/740472 — Posted: 2019-08-20 — Discussion: 2020-07-15  EMBO Press
EZH2 co-opts gain-of-function p53 mutants to promote cancer growth and metastasis
Zhao, Y., Ding, L., Wang, D., Ye, Z., Pan, Y., Ma, L., Coleman, R., Coleman, I., Karnes, R. J., Zhang, J., Nelson, P. S., Wang, L., Zhu, R., Huang, H.
10.1101/298737 — Posted: 2018-04-10 — Discussion: 2020-07-15  EMBO Press
An early Myc-dependent transcriptional program underlies enhanced macromolecular biosynthesis and cell growth during B-cell activation
Amati, B., Sabo, A., Tesi, A., De Pretis, S., Furlan, M., Filipuzzi, M., Morelli, M. J., Andronache, A., Doni, M., Verrecchia, A., Pelizzola, M.
10.1101/561464 — Posted: 2019-02-27 — Discussion: 2020-07-15  EMBO Press
Ubiquitin and SUMO conjugation as biomarkers of Acute Myeloid Leukemias response to chemotherapies
Gatel, P., Brockly, F., Reynes, C., Pastore, M., Hicheri, Y., Cartron, G., Piechaczyk, M., Bossis, G.
10.1101/825182 — Posted: 2019-10-31 — Discussion: 2020-06-04  EMBO Press
Preservation of stemness in high-grade serous ovarian cancer organoids requires low Wnt environment
Hoffmann, K., Berger, H., Kulbe, H., Thillainadarasan, S., Mollenkopf, H.-J., Zemojtel, T., Taube, E., Darb-Esfahani, S., Mangler, M., Sehouli, J., Chekerov, R., Braicu, E., Meyer, T. F., Kessler, M.
10.1101/741397 — Posted: 2019-08-21 — Discussion: 2020-06-04  EMBO Press
The USP28-{triangleup}Np63 axis is a vulnerability of squamous tumours
Prieto-Garcia, C., Hartmann, O., Reissland, M., Braun, F., Fischer, T., Walz, S., Fischer, A., Calzado, M., Orian, A., Rosenfeldt, M., Eilers, M., Diefenbacher, M. E.
10.1101/683508 — Posted: 2019-06-27 — Discussion: 2020-06-04  EMBO Press
Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy
Sahu, A., Sang Lee, J., Zhang, G., Wang, Z., Tian, T., Moll, T., Kasumova, G., Miao, B., Wei, Z., Nair, N. U., Ponomarova, O., Friedman, A., Amzallag, A., Greninger, P., Egan, R., Damon, L., Frederick, D., Jerby-Arnon, L., Wagner, A., Cheng, K., Robinson, W., Park, S. G., Gardner, K., Hannenhalli, S., Gutkind, S., Boland, G., Flaherty, K., Benes, C., Herlyn, M., Bartolome, R., Ruppin, E.
10.1101/284240 — Posted: 2018-03-18 — Discussion: 2019-09-22  EMBO Press

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