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415 Reviews — eLife — Immunology

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Neutrophil-derived IL-17 limits protective host responses and promotes tuberculosis pathogenesis
Sharma, P., Sharma, R. D., Das, M., Sarkar, B., Singh, L., Jain, N., Chaturvedi, S., Mehra, L., Rathee, A., Sharma, S., Shihui, F., Lee, A., Kumar, P. N., Das, P., Viswanathan, V., Kornfeld, H., Howland, S., Babu, S., Nandicoori, V., Singhal, A., Kumar, D.
10.1101/2023.10.05.561061 — Posted: 2023-10-06 — Discussion: 2025-11-20  eLife
Immunoglobulin M regulates airway hyperresponsiveness independent of T helper 2 allergic inflammation.
Hadebe, S., Savulescu, A. F., Khumalo, J., Jones, K., Mangali, S., Mthembu, N., Musaigwa, F., Maepa, W., Ndlovu, H., Ngomti, A., Scibiorek, M., Okendo, J., Brombacher, F.
10.1101/2023.08.02.551636 — Posted: 2023-08-05 — Discussion: 2025-11-19  eLife
Epigenetic adaptation drives monocyte differentiation into microglia-like cells upon engraftment into the retina
Liu, J., Lei, F., Yan, B., Cui, N., Sharma, J., Correa, V., Roach, L., Kikolaou, S., Pitts, K., Chodosh, J., Maidana, D. E., Vavvas, D. G., Zhang, H., Weitz, D., Mostoslavsky, R., Paschalis, E. I.
10.1101/2024.09.09.612126 — Posted: 2024-09-14 — Discussion: 2025-11-14  eLife
HIV-specific CD8+ T-cell responses soon after treatment initiation during acute HIV infection are associated with viral reservoir decline
van Paassen, P. M., Pasternak, A. O., van Dort, K. A., van Nuenen, A. C., Maurer, I., Boeser-Nunnink, B., Buchholtz, N. V. E. J., Mahmoud, T., Lungu, C., van Crevel, R., Rokx, C., Symons, J., Nijhuis, M., van der Veen, A. L. I. P., Vogt, L., Klouwens, M. J., Prins, J. M., Kootstra, N. A., de Bree, G. J.
10.1101/2025.02.24.639839 — Posted: 2025-03-01 — Discussion: 2025-11-14  eLife
B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size
Cho, S. H., Jones, M. A., Meyer, K., Anderson, D. M., Chetyrkin, S., Calcutt, M. W., Caprioli, R. M., Semekovich, C. F., Boothby, M. R.
10.1101/2024.10.17.618760 — Posted: 2024-10-18 — Discussion: 2025-10-29  eLife
RadD from Fusobacterium nucleatum Engages NKp46 to Promote Antitumor Cytotoxicity
Rishiq, A., Galski, J., Bsoul, R., Liu, M., Darawshe, R., Lux, R., Bachrach, G., Mandelboim, O.
10.1101/2025.07.26.666929 — Posted: 2025-07-31 — Discussion: 2025-10-27  eLife
Layers of immunity: Deconstructing the Drosophila effector response
Ryckebusch, F., Tian, Y., Rapin, M., Schupfer, F., Hanson, M. A., Lemaitre, B.
10.1101/2025.03.28.645959 — Posted: 2025-03-31 — Discussion: 2025-10-06  eLife
Clonal stochasticity in early NK cell response to mouse cytomegalovirus is generated by mature subsets of varying proliferative ability
Wethington, D., Potempa, M., Giuliani, G., Aguilar, O. A., Grassmann, S., Stewart, W., Adams, N. M., Sun, J. C., Lanier, L. L., Das, J.
10.1101/2023.09.07.556760 — Posted: 2023-09-08 — Discussion: 2025-09-30  eLife
Epidermal Resident Memory T Cell Fitness Requires Antigen Encounter in the Skin
Weiss, E. S., Hirai, T., Li, H., Liu, A., Baker, S., Magill, I., Gillis, J., Zhang, Y. R., Ramcke, T., Kurihara, K., The ImmGen Consortium OpenSource T cell Project, , Masopust, D., Anandasabapathy, N., Singh, H., Zemmour, D., Mackay, L. K., Kaplan, D. H.
10.1101/2025.03.31.646438 — Posted: 2025-04-05 — Discussion: 2025-09-29  eLife
The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2
Suryawanshi, R. K., Jaishankar, P., Correy, G. J., Rachman, M. M., O'Leary, P. C., Taha, T. Y., Zapatero-Belinchon, F. J., McCavitt-Malvido, M., Doruk, Y. U., Stevens, M. G. V., Diolati, M. E., Jogalekar, M. P., Richards, A. L., Montano, M., Rosecrans, J., Matthay, M., Togo, T., Gonciarz, R. L., Gopalkrishnan, S., Neitz, R. J., Krogan, N. J., Swaney, D. L., Shoichet, B. K., Ott, M., Renslo, A. R., Ashworth, A., Fraser, J. S.
10.1101/2024.08.08.606661 — Posted: 2024-08-09 — Discussion: 2025-09-17  eLife

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