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215 Reviews — eLife — Genetics

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Crispant analysis in zebrafish as a tool for rapid functional screening of disease-causing genes for bone fragility
Debaenst, S., Jarayseh, T., De Saffel, H., Bek, J. W., Boone, M., Josipovic, I., Kibleur, P., Kwon, R. Y., Coucke, P., Willaert, A.
10.1101/2024.06.27.601074 — Posted: 2024-06-28 — Discussion: 2024-12-31  eLife
Intercellular transport of RNA can limit heritable epigenetic changes
Shugarts, N., Yi, A. L., Chan, W. M., Marre, J. A., Sathya, A., Jose, A. M.
10.1101/2021.10.05.463267 — Posted: 2021-10-06 — Discussion: 2024-12-19  eLife
DYRK1A kinase triplication is the major cause of Otitis Media in Down Syndrome
Tateossian, H., Southern, A., Vikhe, P., Lana-Elola, E., Watson-Scales, S., Gibbins, D., Williams, D., Purnell, T., Mburu, P., Parker, A., Norris, D. P., Santos-Cortez, R. L. P., Herrmann, B. W., Wells, S., Lad, H. V., Fisher, E., Tybulewicz, V. L., Brown, S. D. M.
10.1101/2024.10.03.616443 — Posted: 2024-10-03 — Discussion: 2024-12-12  eLife
Irreproducibility of transgenerational learned pathogen-aversion response in C. elegans
Gainey, D. P., Shubin, A. V., Hunter, C. P.
10.1101/2024.06.01.596941 — Posted: 2024-06-03 — Discussion: 2024-12-06  eLife
Swi6/HP1 binding to RNA-DNA hybrids initiates heterochromatin assembly at the centromeric dg-dh repeats in Fission Yeast
Singh, J., Kumar, J., Haldar, S., Gupta, N., Kumar, V., Thakur, M., Chandradoss, K. R., Ghose, D., Dutta, D., Sandhu, K. S.
10.1101/2020.10.21.349050 — Posted: 2020-10-21 — Discussion: 2024-12-03  eLife
Genetic and bioinformatic analyses reveal transcriptional networks underlying dual genomic coordination of mitochondrial biogenesis
Xu, H.
10.1101/2024.01.25.577217 — Posted: 2024-01-29 — Discussion: 2024-11-26  eLife
Sir2 and Fun30 regulate ribosomal DNA replication timing via Mcm helicase positioning and nucleosome occupancy
Lichauco, C., Foss, E. J., Gatbonton-Schwager, T., Athow, N. F., Lofts, B., Acob, R., Taylor, E., Lao, U., Miles, s., Bedalov, A.
10.1101/2024.03.21.586113 — Posted: 2024-03-26 — Discussion: 2024-11-21  eLife
Systematic genetic characterization of the human PKR kinase domain highlights its functional malleability to escape a viral substrate mimic
Chambers, M. J., Scobell, S., Sadhu, M. J.
10.1101/2024.05.29.596416 — Posted: 2024-06-02 — Discussion: 2024-10-23  eLife
Prolonged DNA Damage Checkpoint Arrest Requires Constant Renewal and the Spindle Assembly Checkpoint
Zhou, F. Y., Waterman, D. P., Caban-Penix, S., Eapen, V. V., Haber, J. E.
10.1101/2023.05.15.540538 — Posted: 2023-05-15 — Discussion: 2024-10-17  eLife
Biallelic pathogenic variants in DNAH3 cause male infertility in humans and mice
Wang, X., Shen, G., Yang, Y., Jiang, C., Ruan, T., Yang, X., Zhuo, L., Zhang, Y., Ou, Y., Zhao, X., Long, S., Tang, X., Lin, T., Shen, Y.
10.1101/2024.02.19.580977 — Posted: 2024-02-21 — Discussion: 2024-10-07  eLife

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