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438 Reviews — All Partners — Cancer Biology

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Molecular consequences of acute versus chronic CDK12 loss in prostate carcinoma nominates distinct therapeutic strategies
Frank, S., Persse, T., Coleman, I. M., Bankhead, A., Li, D., DeSarkar, N., Wilson, D., Rudoy, D., Vashisth, M., Galipeau, P., Yang, M., Hanratty, B., Dumpit, R., Morrissey, c., Corey, E., Montgomery, R., Haffner, M., Pritchard, C., Vasioukhin, V., Ha, G., Nelson, P. S.
10.1101/2024.07.16.603734 — Posted: 2024-07-19 — Discussion: 2025-09-24  eLife
Rearrangement of 3D genome organization in breast cancer epithelial - mesenchymal transition and metastasis organotropism
Das, P., San Martin, R., Hong, T., McCord, R. P.
10.1101/2024.08.23.609227 — Posted: 2024-08-25 — Discussion: 2025-09-24  eLife
BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment
Rios-Jimenez, E., Zomer, A., Collot, R., Barrera Roman, M., Ariese, H., L. van Ineveld, R., Kleinnijenhuis, M., Bessler, N., Johnson, H., Rios, A., Alieva, M.
10.1101/2024.08.23.609358 — Posted: 2024-08-27 — Discussion: 2025-09-23  eLife
KDM5 demethylases suppress R-loop-mediated viral mimicry and DNA damage in breast cancer cells
Lau, L., Henderson, K., Turkoz, A., Linker, S., Schlessinger, D., Townsley, B., Egan, B., Ragunathan, S., Rollins, R., Bi, X., Chen, Z. J., Brodsky, O., Restaino, C., Murali, G., Jensen-Pergakes, K., Maaarstig, A., Kermi, C., Moore, P., Classon, M.
10.1101/2025.02.26.640279 — Posted: 2025-03-03 — Discussion: 2025-09-10  eLife
Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma
Bienkowska, K. J., Gallardo, S., Zainal, N., Ellis, M., Lopez, M.-A., Austine, J., Pittla, S., Chee, S. J., Alzetani, A., Shaw, E. C., Ottensmeier, C. H., Thomas, G. J., Hanley, C. J.
10.1101/2024.12.03.626626 — Posted: 2024-12-06 — Discussion: 2025-09-01  Review Commons
Control of mitochondrial dynamics by dPGC1 limits Yorkie-induced oncogenic growth in Drosophila
Sew, W. Q. G., Molano-Fernandez, M., Li, Z., Lange, A., Perez de Ciriza, N., Rasmussen, L. J., Herranz, H.
10.1101/2024.12.02.626378 — Posted: 2025-08-25 — Discussion: 2025-08-25  Review Commons
FAK modulates glioblastoma stem cell energetics via actomyosin contractility: regulation of glycolysis and mitochondrial function
Masalmeh, R. H. A., Dawson, J. C., Garcia, V. A., Muir, M. T., Carter, R. N., Hardingham, G., Davies, C., Graham, R., von Kriegsheim, A., Marques Junior, J., Pednekar, C., Pollard, S. M., Carragher, N. O., Brunton, V. G., Frame, M. C.
10.1101/2024.12.11.627900 — Posted: 2024-12-12 — Discussion: 2025-08-25  Review Commons
Potent synthetic lethality between PLK1 and EYA-family inhibitors in tumours of the central and peripheral nervous system
Nelson, C. B., Wells, J. K., Kesarwani, E., Sobinoff, A. P., Gao, J., MacKenzie, K. L., Poulos, R. C., Nawaz, U., Wang, X., Ford, H. L., Pickett, H. A.
10.1101/2025.01.19.633804 — Posted: 2025-01-22 — Discussion: 2025-08-14  Review Commons
Telomeres control regulation of the human Telomerase (hTERT) gene through non-telomeric TRF2 and independent of Telomere looping
Sengupta, A., Vinayagamurthy, S., Soni, D., Deb, R., Mukherjee, A. K., Dutta, S., Jaiswal, J., Yadav, M., Sharma, S., Bagri, S., Roy, S. S., Singh, A., Khanna, D., Bhatt, A. K., Sharma, A., Saurav, S., Motiani, R. K., Chowdhury, S.
10.1101/2023.10.09.561466 — Posted: 2023-10-10 — Discussion: 2025-08-04  eLife
Reconfiguration of tumor cells with LCOR transcription factor mRNA nanotherapy to enhance immunotherapy efficacy
Serra-Mir, G., Haro-Martiez, E., Cannata, C., Palomeque, J. A., Blasco-Benito, S., Lopez-Plana, A., Sanz-Flores, M., Sabartes, M., Fornaguera, C., Celia-Terrassa, T.
10.1101/2025.04.02.646434 — Posted: 2025-04-03 — Discussion: 2025-07-27  Review Commons

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