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428 Reviews — All Partners — Cancer Biology

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Cancer cells differentially modulate mitochondrial respiration to alter redox state and enable biomass synthesis in nutrient-limited environments
Chang, S. M., Bin Munim, M., Trojan, S. E., Shevzov-Zebrun, A., Abbott, K. L., Vander Heiden, M. G.
10.1101/2025.05.09.653205 — Posted: 2025-05-10 — Discussion: 2025-06-27  eLife
Design of combination therapeutics from protein response to drugs in ovarian cancer cells
Franz, A., Shen, C., Coscia, F., Munroe, K., Charaoui, L., Korkut, A., Mann, M., Luna, A., Sander, C.
10.1101/2025.04.28.651139 — Posted: 2025-05-02 — Discussion: 2025-06-25  eLife
PA2gamma promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP
Wang, J., Shi, Y., Wang, Y., Shen, Y., Liu, H., Sun, S., Wang, Y., Zhou, X., Zhou, Y., Zeng, X., Li, J., Chen, Q.
10.1101/2024.07.23.604769 — Posted: 2024-07-23 — Discussion: 2025-06-10  eLife
PRMT1-Mediated Metabolic Reprogramming Promotes Leukemogenesis
Su, H., Sun, Y., Guo, H., Sun, C.-w., Chen, Q., Liu, S., Li, A., Gao, M., Zhao, R., Raffel, G., Jin, J., Qu, C.-K., Yu, M., Klug, C. A., Zheng, Y. G., Ballinger, S., Kutny, M., Long Zheng, X., Chong, Z., Senevirathne, C., Gross, S., Chen, Y., Luo, M., Zhao, X.
10.1101/2024.12.12.628174 — Posted: 2024-12-17 — Discussion: 2025-06-04  eLife
Reduced mitochondrial transcription sensitizes acute myeloid leukemia cells to BCL-2 inhibition
Arabanian, L. S., Adamsson, J., Unger, A., Di Lucrezia, R., Bergbrede, T., Ashouri, A., Larsson, E., Nussbaumer, P., Klebl, B. M., Palmqvist, L., Gustafsson, C. M.
10.1101/2022.09.23.509145 — Posted: 2022-09-25 — Discussion: 2025-05-30  eLife
NOLC1 Suppresses Immuno-chemotherapy by Inhibiting p53-mediated Ferroptosis in Gastric Cancer
Zhao, S., Lin, J., Zhu, B., Jin, Y., Dong, Q., Ruan, X., Jin, D., Yi, Y., Bai, B., Li, H., Liang, D., Lu, J., Meng, L., Wang, X., Cui, Y., Gu, Y., Shen, X., Lu, X., Rao, S., Sun, W.
10.1101/2024.11.05.622078 — Posted: 2024-11-07 — Discussion: 2025-05-29  eLife
Subtype-specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Patel, A. Y., Zarrineh, P., Sheth, J. H., Mohan, S., Iqbal, M., Nagarajan, S.
10.1101/2025.02.18.638890 — Posted: 2025-02-19 — Discussion: 2025-05-28  Review Commons
Drug-Induced p53 Activation Promotes Acinar Cell Identity and Prevents Pancreatic Cancer Initiation
Twardowski, J. J., Heist, T. I., Soares, Z. G., Berry, E. S., Ruffolo, L. I., Proschel, C., Mello, S. S.
10.1101/2024.05.29.595146 — Posted: 2024-06-02 — Discussion: 2025-05-23  Review Commons
Single-cell dissection of prognostic architecture and immunotherapy response in Helicobacter pylori infection associated gastric cancer
Zhang, X., Zhang, G., Sang, S., Fei, Y., Cao, X., Song, W., Liu, F., Che, J., Tao, H., Wang, H., Zhang, L., Guan, Y., Rong, S., Pei, L., Yao, S., Wang, Y., Zhang, M., Liu, C.
10.1101/2024.05.31.596846 — Posted: 2024-05-31 — Discussion: 2025-05-21  eLife
Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer
Zhang, C., Zhang, Z., Wu, Y., Cheng, J., Luo, K., Li, Z., Zhang, M., Wang, J., Li, Y.
10.1101/2024.05.21.595220 — Posted: 2024-05-23 — Discussion: 2025-05-21  eLife

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