bioRxiv/medRxiv TRiP Review Activity

50 Reviews — All Partners — Pharmacology and Toxicology

Most recent first Previous |  Page 5: Articles 41-50

{micro}-Theraphotoxin-Pn3a inhibition of Cav3.3 channels reveals a novel isoform-selective drug binding site
McArthur, J. R., Wen, J., Hung, A., Finol-Urdaneta, R. K., Adams, D. J.
10.1101/2021.10.04.463006 — Posted: 2021-10-04 — Discussion: 2021-11-15  eLife
Characterization of the Endogenous DAF-12 Ligand and Its Use as an Anthelmintic Agent in Strongyloides stercoralis
Wang, Z., Cheong, M. C., Tsien, J., Deng, H., Qin, T., Stoltzfus, J. D. C., Jaleta, T. G., Li, X., Lok, J. B., Kliewer, S. A., Mangelsdorf, D. J.
10.1101/2021.09.07.459359 — Posted: 2021-09-08 — Discussion: 2021-11-12  eLife
Covalent inhibition of endoplasmic reticulum chaperone GRP78 disconnects the transduction of ER stress signals to inflammation and lipid accumulation in diet-induced obese mice
Rong, J., Luo, D., Fan, N., Zhang, X., Ngo, F. Y., Zhao, J., Zhao, W., Huang, M., Li, D., Wang, Y.
10.1101/2021.08.20.457085 — Posted: 2021-08-20 — Discussion: 2021-11-10  eLife
Chemogenetic analysis of how receptors for short chain fatty acids regulate the gut-brain axis
Tobin, A. B., Barki, N., Bolognini, D., Borjesson, U., Jenkins, L., Riddell, J., Hughes, D. I., Ulven, T., Hudson, B. D., Ulven, E. R., Dekker, N., Milligan, G.
10.1101/2020.01.11.902726 — Posted: 2020-01-13 — Discussion: 2021-11-04  eLife
Bisphosphonate drugs have actions outside the skeleton and inhibit the mevalonate pathway in alveolar macrophages
Rogers, M. J., Munoz, M. A., Fletcher, E. K., Skinner, O. P., Jurczyluk, J., Kristianto, E., Hodson, M., Sun, S., Ebetino, F. H., Croucher, D. R., Hansbro, P. M., Center, J. R.
10.1101/2021.08.09.455652 — Posted: 2021-08-10 — Discussion: 2021-11-01  eLife
Predicting drug polypharmacology from cell morphology readouts using variational autoencoder latent space arithmetic
Chow, Y. L., Singh, S., Carpenter, A. E., Way, G. P.
10.1101/2021.09.02.458673 — Posted: 2021-09-03 — Discussion: 2021-11-01  Review Commons
Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity
Babolmorad, G., Latif, A., Pollock, N. M., Domingo, I. K., Delyea, C., Rieger, A. M., Allison, W. T., Bhavsar, A. P.
10.1101/2020.06.19.162057 — Posted: 2020-06-20 — Discussion: 2021-04-07  EMBO Press
PLZF is a new substrate of CRBN with thalidomide and 5-hydroxythalidomide
Yamanaka, S., Murai, H., Saito, D., Abe, G., Tokunaga, E., Iwasaki, T., Takahashi, H., Takeda, H., Suzuki, T., Shibata, N., Tamura, K., Sawasaki, T.
10.1101/2020.02.28.969071 — Posted: 2020-02-28 — Discussion: 2021-04-02  EMBO Press
Development of a small molecule that corrects misfolding and increases secretion of Z α1-antitrypsin
Lomas, D., Irving, J. A., Arico-Muendel, C., Belyanskaya, S., Brewster, A., Brown, M. J. B., Chung, C.-w., Dave, H., Denis, A., Dodic, N., Dossang, A., Eddershaw, P., Klimaszewska, D., Haq, I., Holmes, D., Hutchinson, J., Jagger, A. M., Jakhria, T., Jigorel, E., Liddle, J., Lind, K., Marciniak, S. J., Messer, J., Neu, M., Olszewski, A., Ordonez, A., Ronzoni, R., Rowedder, J., Rüdiger, M., Skinner, S., Smith, K., Terry, R., Trottet, L., Uings, I., Wilson, S., Zhu, Z., Pearce, A. C.
10.1101/2020.07.26.217661 — Posted: 2020-07-28 — Discussion: 2021-04-02  EMBO Press
Database for drug metabolism and comparisons, NICEdrug.ch, aids discovery and design
MohammadiPeyhani, H., Chiappino-Pepe, A., Haddadi, K., Hafner, J., Hadadi, N., Hatzimanikatis, V.
10.1101/2020.05.28.120782 — Posted: 2020-05-30 — Discussion: 2021-03-24  eLife

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