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524 Reviews — All Partners — Immunology

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Protein supersaturation powers innate immune signaling
Rodriguez Gama, A., Miller, T., Lange, J. J., Wu, J., Song, X., Venkatesan, S., Unruh, J., Bradford, W., Halfmann, R.
10.1101/2023.03.20.533581 — Posted: 2023-03-21 — Discussion: 2025-09-12  eLife
Depletion of extracellular asparagine impairs self-reactive T cells and ameliorates autoimmunity in a murine model of multiple sclerosis
Georgiev, P., Johnson, S., Kurmi, K., Hu, S.-H., Han, S., Patterson, D., Nguyen, T., Huang, L., Liang, D., Goldman, N., Conway, T., Creasey, H., Rowe, J., Haigis, M. C., Sharpe, A. H.
10.1101/2025.06.09.658561 — Posted: 2025-06-11 — Discussion: 2025-09-09  eLife
Tolerance to Lung Infection in TWIK2 K+ Efflux Mediated Macrophage Trained Immunity
Thompson, J., Li, Y., Song, Y., Kim, K.-W., Malik, A., Xu, J.
10.1101/2025.05.25.655979 — Posted: 2025-05-28 — Discussion: 2025-09-09  eLife
Type I and type III interferon receptor knockout chickens: Novel models for unraveling interferon dynamics in influenza infection
Alhussien, M., Vikkula, H. K., Klinger, R., Zenner, C., Frueh, S. P., Negi, R., von Heyl, T., Schleibinger, S., Brunner, M., Berghof, T. V., Schade, B., Aboukhadra, B., Rautenschlein, S., Preisinger, R., Sid, H., Schusser, B.
10.1101/2025.01.24.634794 — Posted: 2025-01-27 — Discussion: 2025-09-09  eLife
The metabolic cofactor Coenzyme A enhances alternative macrophage activation via MyD88-linked signaling
Jones, A. E., Rios, A., Ibrahimovic, N., Chavez, C., Bayley, N. A., Ball, A. B., Hsieh, W. Y., Sammarco, A., Bianchi, A. R., Cortez, A. A., Graeber, T. G., Hoffmann, A., Bensinger, S. J., Divakaruni, A. S.
10.1101/2024.03.28.587096 — Posted: 2024-03-31 — Discussion: 2025-09-08  Review Commons
The synovial lining macrophage layer develops in the first weeks of life in a CSF1- and TGFβ- dependent but monocyte-independent process.
Magalhaes Pinto, M., Malengier-Devlies, B., Seuzaret, G., Ahlback, A., Becker, S., Patatsos, K., Drakoulis, G., Karjalainen, J., Ruedl, C., Voehringer, D., Bain, C., Emmerson, E., Schonfeldova, B., Zec, K., Udalova, I. A., Simakou, T., MacDonald, L., Kurowska-Stolarska, M., Miotla-Zarebska, J., Vincent, T., Ricci, R., Erbs, E., Barrington, J., McColl, B., Neag, G., Kemble, S., Mahony, C., Croft, A., Boon, L., Migotsky, N., Killian, M., Brahim, O. B., Uderhardt, S., Gallerand, A., IVANOV, S., Gentek, R.
10.1101/2025.05.21.655269 — Posted: 2025-05-26 — Discussion: 2025-09-05  Review Commons
Tuberculosis susceptibility in genetically diverse mice reveals functional diversity of neutrophils
Ravesloot-Chavez, M. M., Van Dis, E., Fox, D., Nguyenla, X. H., Rawal, S. L., Ballinger, M. A., Thomas, H., Kotov, D. I., Vance, R., Nachman, M., Stanley, S.
10.1101/2023.06.29.547125 — Posted: 2023-06-30 — Discussion: 2025-08-29  eLife
IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion
Aldridge, D. L., Lanzar, Z., Phan, A., Christian, D. A., Pardy, R., Min, B., Kedl, R., Hunter, C.
10.1101/2025.01.15.633135 — Posted: 2025-01-19 — Discussion: 2025-08-29  eLife
Myc Dysregulation in Activated Macrophages Initiates Iron-Mediated Lipid Peroxidation that Fuels Type I Interferon and Compromises TB Resistance
Yabaji, S. M., Zhernovkov, V., Araveti, P. B., Lata, S., Rukhlenko, O. S., Abdullatif, S. A., Alekseev, Y., Ma, Q., Dayama, G., Lau, N. C., Bishai, W. R., Crossland, N. A., Campbell, J. D., Kholodenko, B. N., Gimelbrant, A. A., Kobzik, L., Kramnik, I.
10.1101/2024.03.05.583602 — Posted: 2024-03-10 — Discussion: 2025-08-29  eLife
Trained innate immunity attenuates macrophage efferocytosis of cancer cells
Chatzis, A., Lukaszonek, J., Lagos, D., Boucher, D., Kourtzelis, I.
10.1101/2024.11.11.622862 — Posted: 2024-11-12 — Discussion: 2025-08-29  eLife

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