bioRxiv/medRxiv TRiP Review Activity

428 Reviews — All Partners — Cancer Biology

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High-dose oncogenic PIK3CA drives constitutive cellular stemness through self-sustained TGFβ pathway activation
Madsen, R. R., Longden, J., Knox, R. G., Robin, X., Völlmy, F., Macleod, K., Moniz, L., Carragher, N., McGranahan, N., Linding, R., Vanhaesebroeck, B., Semple, R. K.
10.1101/753830 — Posted: 2019-09-01 — Discussion: 2020-10-28  Review Commons
Phenotypic plasticity and partial EMT underlie local invasion and distant metastasis in colon cancer
Sacchetti, A., Teeuwssen, M., Verhagen, M., Joosten, R., Gusinac, A., Watson, M. M., Stabile, R., Kim, W. K., Ubink, I., van de Werken, H. J., Fumagalli, A., Paauwe, M., van Rheenen, J., Sansom, O. J., Kranenburg, O., Fodde, R.
10.1101/2020.07.24.219238 — Posted: 2020-07-24 — Discussion: 2020-10-26  eLife
The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma
Polaski, J. T., Udy, D. B., Escobar-Hoyos, L. F., Askan, G., Leach, S. D., Ventura, A., Kannan, R., Bradley, R. K.
10.1101/2020.08.14.248864 — Posted: 2020-08-14 — Discussion: 2020-10-22  eLife
DDX5 targets tissue-specific RNAs to promote intestine tumorigenesis
Abbasi, N., Long, T., Li, Y., Ma, E., Yee, B. A., Patel, P. R., Sayed, I. M., Varki, N., Das, S., Ghosh, P., Yeo, G. W., Huang, W. J. M.
10.1101/2020.03.25.006668 — Posted: 2020-03-26 — Discussion: 2020-10-06  EMBO Press
The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism
Xu, R., Jones, W., Wilcz-Villega, E., Costa, S., Rajeeve, V., Bentham, R. B., Bryson, K., Nagano, A., Yaman, B., Olendo Barasa, S., Wang, Y., Chelala, C., Cutillas, P., Szabadkai, G., Frezza, C., Bianchi, K.
10.1101/855361 — Posted: 2019-11-26 — Discussion: 2020-10-06  EMBO Press
Reprogrammed mRNA translation drives metabolic response to therapeutic targeting of ribosome biogenesis
Kusnadi, E. P., Trigos, A. S., Cullinane, C., Goode, D. L., Larsson, O. S., Devlin, J. R., Chan, K. T., DeSouza, D. P., McConville, M. J., McArthur, G. A., Thomas, G., Sanij, E., Poortinga, G., Hannan, R. D., Hannan, K. M., Kang, J., Pearson, R. B.
10.1101/847723 — Posted: 2019-11-20 — Discussion: 2020-10-06  EMBO Press
A statistical framework for assessing pharmacological response and biomarkers with confidence
Wang, D., Hensman, J., Kukaite, G., Toh, T. S., GDSC Screening Team, , Dry, J. R., Saez-Rodriguez, J., Garnett, M., Menden, M. P., Dondelinger, F.
10.1101/2020.05.01.072983 — Posted: 2020-05-03 — Discussion: 2020-10-05  eLife
CBX2 and CBX7 antagonistically regulate metabolic reprogramming in breast cancer
Iqbal, M. A., Siddiqui, S., Ur Rehman, A., Siddiqui, F. A., Singh, P., Kumar, B., Saluja, D.
10.1101/2020.08.06.239129 — Posted: 2020-08-06 — Discussion: 2020-09-30  eLife
HIP1 mediates oncogenic transformation and cancer progression through STAT3 signalling
Roheet Bantval Rao, Antonio Ramos-Montoya, Helen Scott, Lorraine Berry, Stefanie Reichelt, Stewart MacArthur, Roslin Russell, David E Neal, Emma Evergren, Ian G Mills
10.1101/2020.07.09.191734 — Posted: 2020-07-09 — Discussion: 2020-09-15  eLife
Ral GTPases promote metastasis by controlling biogenesis and organ colonization of exosomes
Shima Ghoroghi, Benjamin Mary, Annabel Larnicol, Annick Klein, Nael Osmani, Ignacio Busnelli, Francois Delalande, Nicodeme Paul, Sebastien Halary, Frederic Gros, Laetitia Fouillen, Anne-Marie Haeberle, Cathy Royer, Coralie Spiegelhalter, Gwennan Andre-Gregoire, Kendelle Murphy, Paul Timpson, Raphael Carapito, Marcel Blot-Chabaud, Julie Gavard, Christine Carapito, Nicolas Vitale, Olivier Lefebvre, Jacky G. Goetz, Vincent Hyenne
10.1101/2020.07.10.196691 — Posted: 2020-07-10 — Discussion: 2020-09-10  eLife

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