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257 Reviews — eLife — Molecular Biology

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PI3Kalpha inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification
Valer, J. A., Deber, A., Wits, M., Pimenta, C., Goumans, M. J., Rosa, J. L., Sanchez-Duffhues, G., Ventura, F.
10.1101/2023.09.14.557704 — Posted: 2023-09-14 — Discussion: 2025-05-23  eLife
PDZ-directed substrate recruitment is the primary determinant of specific 4E-BP1dephosphorylation by PP1-Neurabin
Fedoryshchak, R. O., El-Bouri, K., Joshi, D., Mouilleron, S., Treisman, R.
10.1101/2024.09.23.614477 — Posted: 2024-09-23 — Discussion: 2025-05-09  eLife
Executioner caspase is proximal to Fasciclin 3 which facilitates non-lethal activation in Drosophila olfactory receptor neurons
Muramoto, M., Hanawa, N., Okumura, M., Chihara, T., Miura, M., Shinoda, N.
10.1101/2023.07.20.549821 — Posted: 2023-07-20 — Discussion: 2025-04-16  eLife
Rtf1 HMD domain facilitates global histone H2B monoubiquitination and regulates morphogenesis and virulence in the meningitis-causing pathogen Cryptococcus neoformans
Jiang, Y., Zhao, F., Liang, Y., Lu, Z., Wang, S., Meng, Y., Liu, Z., Zhang, J., Zhao, Y.
10.1101/2024.05.20.594937 — Posted: 2024-05-20 — Discussion: 2025-04-14  eLife
SFSWAP is a negative regulator of OGT intron detention and global pre-mRNA splicing
Govindan, A., Conrad, N. K.
10.1101/2024.10.14.618288 — Posted: 2024-10-17 — Discussion: 2025-04-04  eLife
Inhibition of mitochondrial protein import and proteostasis by a pro-apoptotic lipid
Fita-Torro, J., Garrido-Huarte, J. L., Michel, A. H., Kornmann, B., Pascual-Ahuir, A., Proft, M.
10.1101/2023.11.06.565743 — Posted: 2023-11-07 — Discussion: 2025-04-03  eLife
In silico screening by AlphaFold2 program revealed the potential binding partners of nuage-localizing proteins and piRNA-related proteins
Kawaguchi, S., Xu, X., Soga, T., Yamaguchi, K., Kawasaki, R., Shimouchi, R., Date, S., Kai, T.
10.1101/2024.07.28.605023 — Posted: 2024-07-29 — Discussion: 2025-03-24  eLife
Optogenetic control of Protein Kinase C-epsilon activity reveals its intrinsic signaling properties with spatiotemporal resolution
Ong, Q., Lim, C. J. Y., Liao, Y., Ng, J. T.-Y., Lim, L. T. R., Koh, S. X. Y., Chan, S. E., Lee, P. Y. Y., Lim, H., Ye, C. R., Wang, L. C., Ler, S. G., Sobota, R. M., Tan, Y. S., I. Shulman, G., Yang, X., Han, W.
10.1101/2025.01.06.631444 — Posted: 2025-01-08 — Discussion: 2025-03-24  eLife
Acute Activation of Genes Through Transcriptional Condensates Impact Non-target Genes in a Chromatin Domain
Bohra, D., Islam, Z., Nidharshan, S., Mazumder, A., Notani, D.
10.1101/2024.08.26.609711 — Posted: 2024-08-26 — Discussion: 2025-03-18  eLife
Cryo-EM analysis on magnetic beads for scarce macromolecules in heterogeneous samples
Arimura, Y., Konishi, H. A., Funabiki, H.
10.1101/2024.01.21.576499 — Posted: 2024-01-22 — Discussion: 2025-03-12  eLife

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