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281 Reviews — eLife — Molecular Biology

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An ancient competition for the conserved branchpoint sequence influences physiological and evolutionary outcomes in splicing
Pereira de Castro, K. L., Abril, J. m., Liao, K.-C., Hao, H., Donohue, J. P., Russell, W. K., Fagg, W. S.
10.1101/2024.10.09.617384 — Posted: 2024-10-09 — Discussion: 2025-12-12  eLife
ADMA-histones define genomic loading of Rhino at the initial step of piRNA cluster formation
Saito, R., Ishizu, H., Harigai, R., Murano, K., Siomi, M. C.
10.1101/2024.03.15.585151 — Posted: 2024-03-15 — Discussion: 2025-12-10  eLife
Dietary sulfur amino acid restriction elicits a cold-like transcriptional response in inguinal but not epididymal white adipose tissue of male mice
Ruppert, P. M., Gueller, A. S., Rosendal, M., Stanic, N., Kornfeld, J.-W.
10.1101/2025.08.06.669020 — Posted: 2025-08-08 — Discussion: 2025-12-04  eLife
Insights from aquaporin structures into drug-resistant sleeping sickness
Matusevicius, M., Corey, R. A., Gragera, M., Yamashita, K., Sprenger, T., Ungogo, M., Blaza, J. N., Castro-Hartmann, P., Chirgadze, D. Y., Chaitanya Vedithi, S., Afanasyev, P., Melero, R., Warshamanage, R., Gusach, A., Carazo, J.-M., Carrington, M., Blundell, T., Murshudov, G. N., Stansfeld, P. J., Sansom, M. S., De Koning, H. P., Tate, C. G., Weyand, S.
10.1101/2025.05.15.654314 — Posted: 2025-05-17 — Discussion: 2025-10-30  eLife
Cryo-EM Reveals Regulatory Mechanisms Governing Substrate Selection and Activation of Human LONP1
Mindrebo, J. T., Alexandrescu, L., Baker, J. R., Wang, G., Lander, G. C.
10.1101/2025.09.05.674599 — Posted: 2025-09-06 — Discussion: 2025-10-30  eLife
Endogenous Real Time Imaging Reveals Dynamic Chromosomal Mobility During Ligand-Mediated Transcriptional Burst Events
Wang, S., Suter, T., Gamliel, A., Kim, Y., Nair, S. J., Oh, S., Yang, F., Ohgi, K. A., Wagner, T., Gan, S., Rosenfeld, M. G.
10.1101/2025.08.18.670875 — Posted: 2025-08-19 — Discussion: 2025-10-27  eLife
Cohesin still drives homologous recombination repair of DNA double-strand breaks in late mitosis.
Ayra Plasencia, J., Symington, L. S., Machin, F.
10.1101/2023.09.08.556828 — Posted: 2023-09-08 — Discussion: 2025-10-20  eLife
Epigenetic delineation of the earliest cardiac lineage segregation by single-cell multi-omics
Xie, P., Jiang, X., He, J., Pan, Q., Yang, X., Zheng, Y., Fan, W., Wu, C., Zheng, W., Fang, K., Si, S., Zhu, S., Yang, Y., Zhong, T. P., Yang, Z., Wei, K., Xie, W., Jing, N., Luo, Z., Lin, C.
10.1101/2024.05.17.594655 — Posted: 2024-05-17 — Discussion: 2025-10-16  eLife
Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment
Tolman, N., Li, T., Balasubramanian, R., Li, G., Bupp-Chickering, V., Kelly, R. A., Simon, M., Peregrin, J., Montgomery, C., Stamer, W. D., Qian, J., John, S. W. M.
10.1101/2024.11.01.621152 — Posted: 2024-11-01 — Discussion: 2025-10-10  eLife
Ribosomal RNA synthesis by RNA polymerase I is regulated by premature termination of transcription.
Azouzi, C., Schwank, K., Queille, S., Kwapisz, M., Aguirrebengoa, M., Henras, A., Lebaron, S., Tschochner, H., Lesne, A., Beckouet, F., Gadal, O., DEZ, c.
10.1101/2023.11.27.568781 — Posted: 2023-11-27 — Discussion: 2025-10-10  eLife

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