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268 Reviews — eLife — Cancer Biology

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Inhibition of p38-MK2 pathway enhances the efficacy of microtubule inhibitors in breast cancer cells
Chen, Y.-C., Takada, M., Nagornyuk, A., Muhan, W., Yamada, H., Nagashima, T., Ohtsuka, M., DeLuca, J. G., Markus, S. M., Takaku, M., Suzuki, A.
10.1101/2024.11.04.621816 — Posted: 2024-11-07 — Discussion: 2025-05-13  eLife
Reduction in ETFDH expression optimizes cancer cell bioenergetics
Papadopoli, D., Palia, R., Jovanovic, P., Tabaries, S., Ciccolini, E., Sabourin, V., Igelmann, S., McLaughlan, S., Zhan, L., Kim, H., Chekkal, N., Szkop, K. J., Bertomeu, T., Zeng, J., Vassalakis, J., Afzali, F., Mzoughi, S., Guccione, E., Tyers, M., Avizonis, D., Larsson, O., Postovit, L.-M., Djuranovic, S., Ursini-Siegel, J., Siegel, P. M., Pollak, M., Topisirovic, I.
10.1101/2024.10.25.620155 — Posted: 2024-10-25 — Discussion: 2025-05-09  eLife
Integrated Analysis of Single-Cell and Bulk RNA-Seq Data reveals that Ferroptosis-Related Genes Mediated the Tumor Microenvironment predicts Prognosis, and guides Drug Selection in Triple-Negative Breast Cancer
Gong, X., Gu, L., Yang, D., He, Y., Li, Q., Qin, H., Wang, Y.
10.1101/2024.07.04.602021 — Posted: 2024-07-06 — Discussion: 2025-05-09  eLife
Repression of the Wnt pathway effector TCF7L2 reverses lethal cachexia in mice with intestinal cancers
Leong, M. L., Ruedl, C., Karjalainen, K.
10.1101/2024.11.22.624913 — Posted: 2024-11-25 — Discussion: 2025-05-07  eLife
Human RAP2A Homolog of the Drosophila Asymmetric Cell Division Regulator Rap2l Targets the Stemness of Glioblastoma Stem Cells
Franco, M., Gargini, R., Barbera, V. M., Saceda, M., Carmena, A.
10.1101/2025.01.28.635292 — Posted: 2025-02-03 — Discussion: 2025-05-01  eLife
Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
Li, S., Song, K., Sun, H., Tao, Y., Huang, A., Bhatia, V., Hanratty, B., Patel, R. A., Long, H. W., Morrissey, C., Haffner, M. C., Nelson, P. S., Graeber, T. G., Lee, J. K.
10.1101/2025.02.12.637904 — Posted: 2025-02-17 — Discussion: 2025-04-30  eLife
Tumor Cell Spatial Organization Directs EGFR/RAS/RAF Pathway Primary Therapy Resistance through YAP Signaling
Nakagawa, R., Beardsley, A., Durney, S., Hayward, M.-K., Subramanyam, V., Meyer, N. P., Wismer, H., Goodarzi, H., Weaver, V. M., Van de Mark, D., Goga, A.
10.1101/2024.09.26.615226 — Posted: 2024-09-28 — Discussion: 2025-04-25  eLife
Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis
Jonker, P. B., Sadullozoda, M., Cognet, G., Saab, J. J. A., Sokol, K. H., Wu, V. X., Kumari, D., Sheehan, C., Ozgurses, M. E., Agovino, D., Croley, G., Patel, S. A., Bock-Hughes, A., Macleod, K. F., Shah, H., Coloff, J. L., Lien, E. C., Muir, A.
10.1101/2025.03.10.642426 — Posted: 2025-03-13 — Discussion: 2025-04-23  eLife
A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial-mesenchymal transition and stemness in breast cancer
Usman, S., Yeudall, W. A., Teh, M.-T., Ghaloum, F., Tummala, H., Waseem, A.
10.1101/2024.11.13.623301 — Posted: 2024-11-15 — Discussion: 2025-04-22  eLife
Targeting SLC7A11-mediated cysteine metabolism for the treatment of trastuzumab resistant HER2 positive breast cancer
Hua, Y., Duan, N., Sun, C., Yang, F., Tian, M., Sun, Y., Zhao, S., Gong, J., Liu, Q., Huang, X., Liang, Y., Fu, Z., Li, W., Yin, Y.
10.1101/2024.11.12.623302 — Posted: 2024-11-15 — Discussion: 2025-04-22  eLife

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