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285 Reviews — eLife — Cancer Biology

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Single-Cell Atlas of AML Reveals Age-Related Gene Regulatory Networks in t(8;21) AML
Whittle, J., Meyer, S., Lacaud, G., Baker, S. M., Iqbal, M.
10.1101/2024.10.29.620871 — Posted: 2024-11-03 — Discussion: 2025-11-12  eLife
Pharmacologic inhibition of BAF chromatin remodeling complexes as a therapeutic approach to transcription factor-dependent cancers
Centore, R. C., Soares, L. M. M., Topal, S., Vaswani, R. G., Ichikawa, K., Li, Z., Fan, H., Setser, J. W., Lahr, D. L., Zawadzke, L. E., Chen, X., Barnash, K. D., Muwanguzi, J., Anthony, N., Sandoval, G. J., Feldman, K., Elliott, G., Adam, A., Huang, D., Davenport, Y., Schiller, S., Wilson, K. J., Voigt, J., Xu, L., Hentemann, M., Millan, D. S., Chan, H. M., Decicco, C. P., Kruger, R. G., Bellon, S. F.
10.1101/2023.09.11.557162 — Posted: 2023-09-15 — Discussion: 2025-11-12  eLife
Therapeutic benefits of maintaining CDK4/6 inhibitors and incorporating CDK2 inhibitors beyond progression in breast cancer
Armand, J., Kim, S., Kim, K., Son, E., Kim, M., Yang, H. W.
10.1101/2024.11.11.623139 — Posted: 2024-11-15 — Discussion: 2025-11-07  eLife
Multi-gradient Permutation Survival Analysis Identifies Mitosis and Immune Signatures Steadily Associated with Cancer Patient Prognosis
Cai, X., Ye, Y., Liu, X., Fang, Z., Chen, L., Li, F., Ji, H.
10.1101/2024.02.20.581166 — Posted: 2024-02-22 — Discussion: 2025-11-04  eLife
Human RAP2A Homolog of the Drosophila Asymmetric Cell Division Regulator Rap2l Targets the Stemness of Glioblastoma Stem Cells
Franco, M., Gargini, R., Barbera, V. M., Saceda, M., Carmena, A.
10.1101/2025.01.28.635292 — Posted: 2025-02-03 — Discussion: 2025-10-31  eLife
Blocking Osteoprotegerin Reprograms Cancer Associated Fibroblast to Promotes Immune Infiltration into the Tumor Microenvironment
Wang, Y., Apostolopoulou, H., Sun, I. H., Bains, A., Gibbs, D., Huang, S., Alliston, T., Maker, A., Tlsty, T., Ntranos, V., Gardner, J. M., Bhushan, A.
10.1101/2025.07.04.663190 — Posted: 2025-07-07 — Discussion: 2025-10-17  eLife
Circulating bile acid levels direct sex-differences in liver cancer development
Patton, M. E., Kelekar, S., Taylor, L. J., Thakare, R., Lee, S., Alnouti, Y., Madak-Erdogan, Z., Lee, J.-S., Finegold, M. J., Anakk, S.
10.1101/2020.06.25.172635 — Posted: 2020-06-27 — Discussion: 2025-10-10  eLife
Degradation of LMO2 in T cell leukaemia causes collateral breakdown of transcription complex partners and LMO2-dependent apoptosis
Sereesongsaeng, N., Bataille, C., Russell, A., Bery, N., Sialana, F., Choudhary, J., Miller, A., Rabbitts, T.
10.1101/2024.12.09.627495 — Posted: 2024-12-09 — Discussion: 2025-10-10  eLife
Repression of PRMT activities sensitize homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment
Zhang, Y., Xu, M., Yuan, J., Hu, Z., Jiang, J., Huang, J., Wang, B., Shen, J., Long, M., Fan, Y., Montone, K. T., Tanyi, J., Tavana, O., Chan, H. M., Hu, X., Zhang, L.
10.1101/2024.05.21.595159 — Posted: 2024-05-21 — Discussion: 2025-09-25  eLife
Integrative single cell and spatial transcriptomics of colorectal cancer reveals multicellular functional units that support tumor progression
Avraham-Davidi, I., Mages, S., Klughammer, J., Moriel, N., Imada, S., Hofree, M., Murray, E., Chen, J., Pelka, K., Mehta, A., Boland, G. M., Delorey, T. M., Caplan, L., Dionne, D., Tirosh, I., Hacohen, N., Chen, F., Yilmaz, O. H., Roper, J., Rozenblatt-Rosen, O., Nitzan, M., Regev, A.
10.1101/2022.10.02.508492 — Posted: 2022-10-02 — Discussion: 2025-09-25  eLife

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